Junjie Wang

ORCID: 0000-0002-6277-7531
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Research Areas
  • Management of metastatic bone disease
  • Advanced Radiotherapy Techniques
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Lung Cancer Diagnosis and Treatment
  • Anatomy and Medical Technology
  • Brain Metastases and Treatment
  • Surgical Simulation and Training
  • Immunotherapy and Immune Responses
  • Esophageal Cancer Research and Treatment
  • T-cell and B-cell Immunology
  • Pelvic and Acetabular Injuries
  • Cerebrospinal fluid and hydrocephalus
  • Surgical site infection prevention
  • Medical Imaging and Analysis
  • Immune Cell Function and Interaction
  • Bone fractures and treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Orthopedic Infections and Treatments
  • ECG Monitoring and Analysis
  • Musculoskeletal Disorders and Rehabilitation
  • Neurosurgical Procedures and Complications
  • Sarcoma Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Radiation Dose and Imaging

Sichuan University
2025

Peking University
2009-2024

Peking University Third Hospital
2009-2024

Second Xiangya Hospital of Central South University
2022-2024

Central South University
2022-2024

Zhejiang Chinese Medical University
2023

Abstract CD4(+)CD25(+) regulatory T cells (Treg cells) are an important subset of for keeping proper immune responses and tolerance. However, the effects gamma radiation on CD4(+)CD25(high) Foxp3(+) Treg have not been examined previously. In present study, we compared sensitivity mouse CD4(+)CD25(-) to in vitro vivo. After C57BL/6 mice received a whole-body dose 5 Gy rays, numbers lymphocyte subsets blood, lymph nodes, spleens thymuses clearly decreased. significantly enhanced ratios CD4(+)...

10.1667/rr0978.1 article EN Radiation Research 2009-10-08

Hydrocephalus, whether arising from post-hemorrhagic or post-traumatic origins, poses significant challenges in clinical management. Lumboperitoneal shunting (LPS) emerges as a viable therapeutic intervention, yet comparative analyses between these etiologies remain scarce. This retrospective study aims to compare the efficacy and safety of LPS placement patients with (PHH) hydrocephalus (PTH). investigates outcomes aged 18 years older diagnosed PHH PTH who underwent 2014 2018. Primary...

10.1038/s41598-024-84158-w article EN cc-by-nc-nd Scientific Reports 2025-01-02

Management of spinal neoplasms has relied on open surgery and external beam radiotherapy (EBRT). Although primary tumors are rare, their treatment remains a pervasive problem. This analysis sought to evaluate the safety efficacy CT-guided 125I seed brachytherapy for recurrent paraspinous vertebral tumors. From November 2002 June 2014, 17 patients who met inclusion criteria were retrospectively reviewed. 14 (82.4%) had previously undergone surgery, 15 (88.2%) received conventional EBRT 3...

10.1186/s13014-014-0301-8 article EN cc-by Radiation Oncology 2014-12-01

To evaluate the efficacy and safety of 125I seeds implantation for refractory chest wall (CW) metastasis or recurrence under CT guidance. In addition we assessed initial data obtained on therapeutic response CW recurrence. Twenty consecutive patients underwent permanent (from Jul. 2004 to Jan. 2011) computed tomography (CT) Postoperative dosimetry was routinely performed all patients. The actuarial D90 implanted ranged from 100 Gy 160 (median: 130 Gy). activity 0.5 mCi 0.78 0.71 mCi). total...

10.7785/tcrt.2012.500402 article EN Technology in Cancer Research & Treatment 2014-02-06

The aim of this study is to evaluate the feasibility, safety, and clinical efficacy CT-guided 125I seed interstitial brachytherapy in patients with recurrent spinal metastases after external beam radiotherapy (EBRT). Between August 2003 September 2015, 26 metastatic lesions (24 patients) were reirradiated by salvage therapy modality. Treatment for all was preplanned using a three-dimensional treatment planning system 3-5 days before brachytherapy; dosimetry verification performed immediately...

10.1155/2016/8265907 article EN cc-by BioMed Research International 2016-01-01

Abstract Objective This study aims to analyze setup errors in pelvic Volumetric Modulated Arc Therapy (VMAT) for patients with non‐surgical primary cervical cancer, utilizing the onboard iterative kV cone beam CT (iCBCT) imaging system on Varian Halcyon 2.0 ring gantry structure accelerator enhance radiotherapy precision. Method We selected 132 cancer who underwent VMAT daily iCBCT guidance. Before each treatment session, a registration method based bony was employed acquire images...

10.1002/acm2.14480 article EN cc-by Journal of Applied Clinical Medical Physics 2024-08-09

This study aimed to explore the role of three-dimension (3D) printed models in orthopedic resident training tibial plateau fractures. A total 41 residents from our institution were divided into two groups. The intervention group, consisting 20 residents, had access 3D-printed illustrating thirteen In contrast, control comprising 21 received digital images identical Evaluation learning outcomes included accurate identification fracture patterns, deduction traumatic mechanisms, preoperative...

10.1038/s41598-024-76217-z article EN cc-by-nc-nd Scientific Reports 2024-10-22

Introduction Several studies have examined the risk factors for post-percutaneous kyphoplasty (PKP) refractures and developed many clinical prognostic models. However, no prior research exists using Random Forest (RF) model, a favored tool model development, to predict occurrence of new vertebral compression fractures (NVCFs). Therefore, this study aimed investigate post-PKP fractures, compare predictive performance logistic regression RF models in forecasting visualize model. Methods We...

10.3389/fninf.2023.1304248 article EN cc-by Frontiers in Neuroinformatics 2023-12-21

To compare the pre-plan and post-plan dosimetric parameter differences of 3D-printed non-coplanar templates (3D-PNCT)-assisted computed tomography (CT)-guided iodine-125 (125I) radioactive seed implantation brachytherapy (RISI) in patients with inguinal lymph node metastasis (ILNM).This was a retrospective study 15 ILNM carcinomas treated 3D-PNCT-assisted CT-guided RISI between May, 2015 April, 2018. All underwent prior external beam radiotherapy (EBRT) or surgery. Dosimetric parameters...

10.5114/jcb.2022.121564 article EN cc-by-nc-sa Journal of Contemporary Brachytherapy 2022-01-01

Abstract Background/objective This multicenter study aimed to explore the efficacy and toxicity of radioactive Iodine-125 seed implantation for lymph node recurrence in patients with esophageal cancer after external radiotherapy. Methods Clinical data eligible from 5 centers China were retrospectively reviewed. A total 126 between January 2016 March 2019 included. The median interval previous radiotherapy was calculated. target volume 2.1–128.1 cm 3 (median, 22.2 ) postoperative D90 is 120.6...

10.1186/s13014-022-02196-y article EN cc-by Radiation Oncology 2023-01-26

目的探讨3D打印共面模板(3D-printed coplanar template,3D-PCT)辅助CT引导125I放射性粒子植入(radioactive 125I seedimplantation,RISI)治疗胸壁转移瘤的技术方法和临床疗效,并分析剂量学参数对疗效的影响。 方法回顾性分析2014年1月-2021年3月于滕州市中心人民医院行3D-PCT辅助CT引导125I粒子植入治疗55例胸壁转移瘤临床资料。术前经TPS制定治疗计划,术中在3D-PCT辅助下行125I粒子植入,术后第3天复查CT进行术后剂量验证。术后定期复查CT计算局部控制率、总生存(OS)率,并评价患者疼痛缓解情况及相关并发症。采用Log-rank检验、Cox回归行单因素、多因素分析局部控制时间(local control time,LCT)的影响因素,受试者工作特征(ROC)曲线分析剂量学参数预测LCT的临界值。...

10.3760/cma.j.issn.0254-5098.2021.11.007 article ZH-CN 2021-11-25
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