A5082814141- Lignin and Wood Chemistry
- Catalysis for Biomass Conversion
- Autophagy in Disease and Therapy
- Biofuel production and bioconversion
- Structural Behavior of Reinforced Concrete
- Thermochemical Biomass Conversion Processes
- Innovative concrete reinforcement materials
- Phagocytosis and Immune Regulation
- Concrete Corrosion and Durability
- Reinforcement Learning in Robotics
- Structural Load-Bearing Analysis
- Adsorption and biosorption for pollutant removal
- Catalysis and Hydrodesulfurization Studies
- Inflammasome and immune disorders
- RNA Interference and Gene Delivery
- Liver Disease Diagnosis and Treatment
- Advanced Sensor and Energy Harvesting Materials
- Supercapacitor Materials and Fabrication
- Extracellular vesicles in disease
- Seismic Performance and Analysis
- Cancer Research and Treatments
- Nanomaterials for catalytic reactions
- Hedgehog Signaling Pathway Studies
- Immunotherapy and Immune Responses
- Epigenetics and DNA Methylation
Fudan University
2016-2025
University of York
2016-2025
UNSW Sydney
2021-2025
Materials Science & Engineering
2021-2025
Shanghai Ninth People's Hospital
2020-2025
Shanghai Jiao Tong University
2009-2025
Chengdu University of Technology
2019-2025
Zhejiang Lab
2025
Wenzhou Medical University
2025
Zhengzhou University
2021-2024
Engineered biochar synergized from copper heteroatoms and CO<sub>2</sub> fosters non-radical persulfate activation for sustainable remediation.
A systematic investigation of the interaction microwave irradiation with microcrystalline cellulose has been carried out, covering a broad temperature range (150 → 270 °C). variety analytical techniques (e.g., HPLC, (13)C NMR, FTIR, CHN analysis, hydrogen-deuterium exchange) allowed for analysis obtained liquid and solid products. Based on these results mechanism microwaves is proposed. Thereby degree freedom enclosed CH2OH groups was found to be crucial. This allows explanation different...
Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is acknowledged as an independent risk factor for cardiovascular which underlines urgent need new medications to DN. Dihydroquercetin (DHQ), important natural dihydroflavone, exerts significant antioxidant, anti-inflammatory, and antifibrotic properties, but its effects on DN have not been investigated yet.We aimed explore kidney protection DHQ rats induced by high-fat diet/streptozotocin in vivo underlying mechanisms...
A new concept is demonstrated for an integrated close to zero waste wheat straw biorefinery combining two novel green technologies, CO2 extraction and low temperature microwave pyrolysis, produce a variety of products, including energy which can be internally recycled sustain the processes. adds value process by extracting secondary metabolites fatty acids, wax esters alcohols. Low pyrolysis (<200 °C) shown use less higher quality oils chars than conventional pyrolysis. The fractionated...
Autoimmune hepatitis (AIH) is a progressive inflammatory disorders of unknown etiology, characterized by immune-mediated destruction hepatocytes and massive production cytokines. Interleukin-1β pleiotropic proinflammatory cytokine well known to be critical in variety autoimmune diseases. However, the role interleukin-1β (IL-1β) AIH still indistinct. Here, we first investigated significance NOD-like receptor protein 3 (NLRP3) inflammasome-dependent IL-1β pathogenesis with murine model induced...
Novel insights into mesoporous silica nanoparticle (MSN)-induced hepatotoxicity and the underlying mechanism, facilitating an increase of biosafety MSNs.
// Ping Song 1, * , Li Ye Jiajun Fan 1 Yubin Xian Zeng Ziyu Wang Shaofei Guoping Zhang 2 Yang 3 Zhonglian Cao Dianwen Ju Department of Biosynthesis & The Key Laboratory Smart Drug Delivery, Ministry Education, School Pharmacy, Fudan University, Shanghai, 201203, P.R. China Institute Biomedical Science, 200032, Instrumental Analysis Center, These authors have contributed equally to this work Correspondence to: Ju, e-mail: dianwenju@fudan.edu.cn Keywords: asparaginase, autophagy,...
There has been a growing interest in advanced technology that transforms biomass-derived feedstock into renewable chemicals. Hydrothermal liquefaction (HTL) of lignin low-molecular-weight fragments (e.g., monomer, dimer, and oligomer), subsequent catalyzed transformations, offer the promise unlocking diverse aromatic products. In consideration diversity feedstocks, we shed light on impact variations structure conversion efficiency. This review aims to present latest advances HTL highlights...
CD47-specific antibodies and fusion proteins that block CD47-SIRPα signaling are employed as antitumor agents for several cancers. Here, we investigated the synergistic effect of simultaneously targeting CD47 autophagy in non-small cell lung cancer (NSCLC). SIRPαD1-Fc, a novel CD47-targeting protein, was generated found to increase phagocytic cytotoxic activities macrophages against NSCLC cells. During this process, markedly triggered, which characterized by three main stages autophagic...
The sustainability of biorefineries can be improved through levoglucosenone production from residual sugars in waste lignin.
Oxygen functionalities on GIO/GO are involved in the formation of active Al sites potentially with a microwave-absorbing ability, which facilitates glucose–fructose isomerisation water.
Diabetic nephropathy (DN) is one of the most lethal complications diabetes mellitus with metabolic disorders and chronic inflammation. Although cytokine IL-22 was initially implicated in pathogenesis inflammatory diseases, recent studies suggested that could suppress responses alleviate tissue injury. Herein, we examined role DN. We found serum levels were significantly downregulated both patients mice The expression further decreased progression DN, whereas gene therapy ameliorated renal...
<h3>Background</h3> Inhibitors targeting VEGF and VEGFR are commonly used in the clinic, but only a subset of patients could benefit from these inhibitors efficacy was limited by multiple relapse mechanisms. In this work, we aimed to investigate role innate immune response anti-angiogenic therapy explore efficient therapeutic strategies enhance against non-small cell lung cancer (NSCLC). <h3>Methods</h3> Three NSCLC tumor models with responses were designed determine immune-related...
The past decades have seen an increasing interest in developing pathways to produce bio-based chemicals from lignocellulosic biomass and organic waste as renewable resources. Using a source of chemical building blocks is critical future sustainable industry. successful development bio-chemicals will also profound impact terms the innovations new polymers materials, solvents, bio-active compounds. This article provides broad review conventional thermal heating, microwave processing,...