A5049874788- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Prenatal Screening and Diagnostics
- Gestational Diabetes Research and Management
- Endometriosis Research and Treatment
- Electrolyte and hormonal disorders
- Pregnancy and Medication Impact
- Blood groups and transfusion
- Nerve Injury and Rehabilitation
- Immune Cell Function and Interaction
- Ectopic Pregnancy Diagnosis and Management
- Blood Coagulation and Thrombosis Mechanisms
- Urological Disorders and Treatments
- Gynecological conditions and treatments
- Anesthesia and Pain Management
- Parvovirus B19 Infection Studies
- Cleft Lip and Palate Research
- Cystic Fibrosis Research Advances
Hadassah Medical Center
2014-2024
Hebrew University of Jerusalem
2013-2024
Clalit Health Services
2020
Hadassah Academic College
2005-2019
University Medical Center
2017
University of Toronto
2009-2016
Mount Sinai Hospital
2009-2016
Lunenfeld-Tanenbaum Research Institute
2009-2016
Sinai Hospital
2012
Coalition for Research in Women's Health
2010
// Inbar Levi 1, * , Hagai Amsalem 2, Aviram Nissan 3 Merav Darash-Yahana 4 Tamar Peretz Ofer Mandelboim 5 Jacob Rachmilewitz 1 Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel 2 Department Obstetrics and Gynecology, Hadassah Hospital-Mount Scopus, The Surgical Oncology Laboratory, Surgery, Mount Sharett Oncology, Lautenberg Center for General Tumor Immunology, Research Israel-Canada, Hebrew University-Hadassah School, These authors have...
Abstract The maternal leukocytes of the first-trimester decidua play a fundamental role in implantation and early development fetus placenta, yet little is known regarding second-trimester decidual environment. Our multicolor flow cytometric analyses human detected an elevation tissue resident neutrophils second trimester. These cells both murine samples were spatially restricted to basalis. In comparison with peripheral blood (PMNs), expressed high levels neutrophil activation markers...
Abstract Objective To determine the natural history and outcome of fetal cardiac tumors. Methods This was a retrospective cohort study all prenatally detected cases tumors at tertiary care center. Results Forty fetuses were identified to have one or several in association with hydrops (18%), ventricular obstruction (30%) and/or arrhythmia (13%). Of 33 rhabdomyoma, three patients elected terminate pregnancy, four offspring died birth 26 (79%) survived. On follow‐up, 95% live‐born rhabdomyomas...
Abstract Objective To determine perinatal outcome in pregnancies with early severe red blood cell (RBC) alloimmunization. Methods This was a retrospective analysis of 30 patients requiring their first intrauterine transfusion (IUT) at < 22 weeks gestation. Timing the IUT based on evaluation either middle cerebral artery peak systolic velocity (MCA‐PSV) or development ascites. Results Thirty‐three per cent had experienced previous fetal death as result RBC Of these alloimmunized...
The objective of the study was to evaluate efficacy and safety combined prophylactic intraoperative internal iliac artery balloon occlusion postoperative uterine embolization in conservative management (uterine preservation) women with invasive placenta undergoing scheduled caesarean delivery.Ten (mean age 35 years) choosing delivery without hysterectomy had preoperative insertion balloons, inflation immediate absorbable gelatin sponge. A retrospective review performed institutional board...
Objective Failing to properly repair damaged DNA drives the ageing process. Furthermore, age-related inflammation contributes manifestation of ageing. Recently, we demonstrated that efficiency diethylnitrosamine (DEN)-induced double-strand breaks (DSBs) rapidly declines with age. We therefore hypothesised age, decline in damage stems from inflammation. Design used DEN-induced mouse livers and compared their resolution different ages following various permutations aimed at manipulating liver...
Abstract Hyperreactio luteinalis (HL) and spontaneous ovarian hyperstimulation syndrome (OHSS) are both rare conditions during pregnancy. The clinical presentation of HL OHSS comparable should be differentiated from carcinoma. We present a case 32‐year‐old woman who was initially seen with markedly enlarged multicystic ovaries ascites in the 13th week spontaneously conceived Ultrasonographic follow‐up magnetic resonance imaging were employed order to avoid exploratory laparotomy rule out...
Congenital megalourethra is a rare urogenital malformation characterized by dilation and elongation of the penile urethra associated with absence or hypoplasia corpora spongiosa cavernosa. Postnatal complications include voiding erectile dysfunction as well renal insufficiency pulmonary hypoplasia. To date, only few prenatally diagnosed cases have been reported. We report on 10 their postnatal/autopsy findings.The study involved retrospective chart review all antenatally in three tertiary...
Aging is associated with progressive decline in cell function and increased damage to macromolecular components. DNA damage, the form of double-strand breaks (DSBs), increases age turn, contributes aging process age-related diseases. strand triggers a set highly orchestrated signaling events known as response (DDR), which coordinates repair. However, whether accumulation result decreased repair capacity, remains be determined. In our study we showed that there resolution foci containing...
This study examines the role of HER1 signaling in differentiation proliferative extravillous trophoblast (EVT) into invasive EVT. Using JAR choriocarcinoma cell line and placental villous explants as experimental models immunohistochemical assessment protein markers EVT (downregulation Cx40 upregulation HER2 alpha1 integrin), we show that ability decidual conditioned medium (DCM) to induce HER1/2 switching was abrogated presence antagonist, AG1478. Similarly, epidermal growth factor (EGF)...
To compare visualization rates for early targeted organ scanning at gestational ages ranging from 11 weeks 3 days to 13 2 versus 14 16 days.We conducted a prospective longitudinal study of patients who presented nuchal translucency (NT) screening and scanning. Extended scanning, including the central nervous system, face neck, chest, heart (including complete echocardiography), digestive abdominal wall, urinary skeleton, umbilical cord with its insertion placenta, was performed on gravidas...
We investigated whether large head circumference (HC) combined with persistent occiput posterior (OP) position is associated higher rates of operative delivery and obstetric neonatal complications than OP deliveries without HC or in anterior (OA) position.Term singleton our centers from January 2010 to December 2014, delivered cephalic OA (n = 41,038) 1,740), were assessed. compared modes, maternal versus deliveries, ≥90th centile <90th position.Persistent was vacuum extraction unplanned...
Re-laparotomy following caesarean delivery (CD) is a rare yet serious complication. The aim of this study was to identify risk factors, diagnostic features and outcomes re-laparotomy.This retrospective cohort reviewed cases re-laparotomy CD performed at Hadassah-Hebrew University Medical Center. Occurrences were identified via the electronic medical record database.During period, 17,213 women underwent CD, which 55 (0.3%) during same hospitalization. Main indications for intra-peritoneal...