A5089297839- Coral and Marine Ecosystems Studies
- Marine and coastal plant biology
- Marine Sponges and Natural Products
- Marine and fisheries research
- Marine Biology and Ecology Research
- Coastal wetland ecosystem dynamics
- Microbial Natural Products and Biosynthesis
- Microbial Community Ecology and Physiology
- Aquaculture Nutrition and Growth
- Marine Toxins and Detection Methods
- Synthetic Organic Chemistry Methods
- Marine Biology and Environmental Chemistry
- Ocean Acidification Effects and Responses
- Marine Bivalve and Aquaculture Studies
- Marine and coastal ecosystems
- Coastal and Marine Management
- Isotope Analysis in Ecology
- Aquaculture disease management and microbiota
- Seaweed-derived Bioactive Compounds
- Synthesis and Biological Activity
- Protist diversity and phylogeny
- Potato Plant Research
- Chemical synthesis and alkaloids
- Plant Disease Resistance and Genetics
- Cholesterol and Lipid Metabolism
Hainan University
2018-2024
People’s Hospital of Rizhao
2018-2022
Chinese Academy of Sciences
2009-2017
South China Sea Institute Of Oceanology
2009-2017
Institute of Oceanology
2009-2017
A.V. Zhirmunsky National Scientific Center of Marine Biology Far Eastern Branch of the Russian Academy of Sciences
2017
East China Normal University
2014-2016
Wenzhou Medical University
2014
University of Chinese Academy of Sciences
2011
Luhuitou fringing reef, which has been seriously affected by human activities and terrestrial runoff, degraded quickly in recent decades. However, direct impact hyperthermal stress probably minimal because of the influence Qiongdong upwelling summer. Seawater temperature anomalies 2010 resulted mean monthly seawater temperatures summer to be 1–2°C higher than same period 3 preceding years. Moderate coral bleaching at reef was observed due high thermal stress. Montipora most susceptible...
Two new prenylgermacrane-type diterpenoids, lobophytumins A and B (1 2), two prenyleudesmane-type C D (3 4), spatane-type E F (5 6), were isolated from the Hainan soft coral Lobophytum cristatum Tixier-Durivault. Their structures, including relative configuration, elucidated by detailed analysis of spectroscopic data comparison with related known compounds. In addition, absolute configuration lobophytumin (3) was tentatively assigned comparing its specific rotation that closely model...
Chemical investigation of the ethanol extract soft coral Sinularia sp. collected from South China Sea led to isolation three new polyoxygenated sterols, (3S,23R,24S)-ergost-5-ene-3β,23α,25-triol (1), (24S)-ergostane-6-acetate-3β,5α,6β,25-tetraol (2), (24S)-ergostane-6-acetate-3β,6β,12β,25-tetraol (3) together with known ones (4-6). The structures, including relative configurations compounds (1-3), were elucidated by detailed analysis spectroscopic data (IR, UV, NMR, MS) and comparison...
Nineteen metabolites with diverse structures, including the rare pyrroloindoline alkaloid verrupyrroloindoline (1), unprecedented highly fused benzosesquiterpenoid verrubenzospirolactone (2), new asteriscane-type sesquiterpenoid 10-deoxocapillosanane D (3), and two cyclopentenone derivatives (4S*,5S*)-4-hydroxy-5-(hydroxymethyl)-2,3-dimethyl-4-pentylcyclopent-2-en-1-one (4) (S)-4-hydroxy-5-methylene-2,3-dimethyl-4-pentylcyclopent-2-en-1-one (5), were isolated from a South China Sea...
Four new steroids, named 7-dehydroerectasteroid F (1), 11α-acetoxyarmatinol A (2), 22,23-didehydroarmatinol (3), and 3-O-acetylhyrtiosterol (4), together with 11 previously described analogues, were isolated from a South China Sea collection of the soft coral Dendronephthya gigantea. The structures steroids elucidated by comprehensive spectroscopic analysis comparison reported data. Compound 1 showed potent protection against H2O2-induced oxidative damage in neuron-like PC12 cells promoting...
Eight new marine steroids, characterized by either the presence of an aromatic ring or a cross-conjugated dienone system in A, were isolated from Hainan soft coral Dendronephthya studeri Ridley. Their structures elucidated on basis detailed spectroscopic analysis and comparison their NMR data with those reported literature.
Four diterpenes, tritoniopsins A–D (1–4), have been isolated from the South China Sea nudibranch Tritoniopsis elegans and its prey, soft coral Cladiella krempfi. They display an unprecedented pyran ring in cladiellane framework, thus representing a novel cladiellane-based diterpene family. Their structures mainly characterized by NMR mass spectrometric techniques, whereas relative configuration of compound 1 was secured X-ray analysis. Antiproliferative assays on tumor nontumor cell lines...
Seven new briarane diterpenoids, gemmacolides G–M (1–7), were isolated together with two known analogues, juncin O and junceellolide C, from the South China Sea gorgonian Dichotella gemmacea. The structures of compounds elucidated by detailed analysis spectroscopic data comparison reported data. In an in vitro bioassay, these exhibited different levels growth inhibition activity against A549 MG63 cells. particular, compound 4 was more active than positive control adriamycin Compounds 7 also...
Although the importance of coral holobionts is widely accepted, relationship between flexibility microbial structure and host very complicated. Particularly, community dynamics stability host-microbe interactions under different thermal stresses remain largely unknown. In present study, we holistically explored physiology growth Acropora hyacinthus in response to increased temperatures (from 26 33°C). We observed that bleaching corals with loss algal symbionts reduced lipids proteins...
Abstract Summer upwelling areas may serve as a thermal refuge for coral reefs under climate change, and the environmental adaptation of scleractinian to environments remains be further understood. In this work, we systematically analyzed how holobionts Galaxea fascicularis respond different between Qiongdong non‐upwelling regions. The presence colder more saline water was found in seasonal region east Hainan Island. Compared with corals environment, from environment generally had higher...
Five new cembrane diterpenoids, named sinuflexibilins A–E (1–5), along with nine other known diterpenoids (6–14), have been isolated from the organic extract of a Hainan soft coral Sinularia sp. Their structures were determined on basis extensive spectroscopic analyses and by comparison their spectral data those related metabolites. Compound 13, flexibilide, exhibited significant inhibitory activity NF-κB activation using cell-based HEK293 luciferase reporter gene assay.
A floristic study of the marine plants and algae at Luhuitou reef, Sanya Bay, Hainan Island, China, was conducted during rainy (October 2008 November 2010) dry seasons (April 2009 February 2012). Specimens were collected in upper subtidal zone (from 0.5 to 3 m depth low tide). total 156 taxa collected, including 143 macrophyte species (90%), 12 blue–green algal (10%), seagrass, Thalassia hemprichii . The most diverse group Rhodophyta (79 or 55%), followed by Chlorophyta (38 25%) then...
Abstract. Diurnal fluctuations in seawater temperature are ubiquitous on tropical reef flats. However, the effects of such dynamic variations early stages corals poorly understood. In this study, we investigated responses larvae and new recruits Pocillopora damicornis to two constant treatments (29 31 °C) diurnally fluctuating (28–31 30–33 °C with daily means 29 °C, respectively) simulating 3 diel oscillations at m depth Luhuitou fringing (Sanya, China). Results showed that thermal stress...
Ten new cembrane-based diterpenes, locrassumins A-G (1-7), (-)-laevigatol B (8), (-)-isosarcophine (9), and (-)-7R,8S-dihydroxydeepoxysarcophytoxide (10), were isolated from a South China Sea collection of the soft coral Lobophytum crassum, together with eight known analogues (11-18). The structures compounds determined by extensive spectroscopic analysis comparison previously reported data. Locrassumin C (3) possesses an unprecedented tetradecahydrobenzo[3,4]cyclobuta[1,2][8]annulene ring...