- Acute Kidney Injury Research
- Spine and Intervertebral Disc Pathology
- Trauma Management and Diagnosis
- Nausea and vomiting management
- Anesthesia and Pain Management
- Dialysis and Renal Disease Management
- Nitric Oxide and Endothelin Effects
- Protein Hydrolysis and Bioactive Peptides
- Autoimmune and Inflammatory Disorders Research
- Myofascial pain diagnosis and treatment
- T-cell and Retrovirus Studies
- Respiratory Support and Mechanisms
- Neonatal Health and Biochemistry
- Adipose Tissue and Metabolism
- Airway Management and Intubation Techniques
- Spondyloarthritis Studies and Treatments
- Renin-Angiotensin System Studies
- Uterine Myomas and Treatments
- Cannabis and Cannabinoid Research
- Social Media in Health Education
- Minimally Invasive Surgical Techniques
- Viral-associated cancers and disorders
- Coenzyme Q10 studies and effects
- Musicians’ Health and Performance
- Biochemical Acid Research Studies
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2025
Charité - Universitätsmedizin Berlin
2020-2024
Humboldt-Universität zu Berlin
2020-2024
Freie Universität Berlin
2020-2024
Istanbul Medipol University
2022-2024
Mersin Üniversitesi
2018
Ege University
2013
ABSTRACT This study demonstrates the feasibility of performing a Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) hysterectomy on patient with complex surgical history, including two renal transplants. The case involves 42‐year‐old female presenting persistent menorrhagia and hypermenorrhea, unresponsive to standard treatments, diagnosed adenomyosis CIN3. A detailed, step‐by‐step procedure vNOTES technique is provided, marking first video article document in such medical...
Objectives: This study aims to estimate the prevalence of rheumatoid arthritis (RA) and spondyloarthritis (SpA) in Turkey using same telephone questionnaire developed for screening RA SpA France used Serbia Lithuania. Material methods: The was performed two steps. In step I, French translated into Turkish validated through a group 200 patients (80 males, 120 females; mean age 44.0±13.1 years; range 19 75 years) followed up at rheumatology departments University Hospitals Antalya Ankara. II,...
BACKGROUND: Acute hyperglycemia is a risk factor for developing acute kidney injury and poor renal outcome in critically ill patients, whereby the role of vasculature remains unclear. We hypothesize that hyperglycemia-associated hyperosmolarity facilitates vasodilation through Piezo1-mediated eNOS (endothelial NO synthase) activation. METHODS: Vasoreactivity was analyzed using wire myography isolated mouse mesenteric arteries interlobar, microvascular perfusion afferent arterioles efferent...
Abstract Background Quadratus lumborum block (QLB) is a fascial plane block. There no randomized study on the efficacy of QLB for lumbar surgery. We evaluated postoperative pain management and patient satisfaction after disc herniation surgery (LDHS). Methods Sixty patients with ASA score I-II planned LDHS under general anesthesia were included. allocated into two groups: group ( n = 30) or control 30). was performed 30 ml 0.25% bupivacaine in group. Paracetamol 1 g IV 3 × ordered to at...
Transient receptor potential channel subfamily C, member 6 (TRPC6), a non-selective cation that controls influx of Ca2+ and other monovalent cations into cells, is widely expressed in the kidney. TRPC6 gene variations have been linked to chronic kidney disease but its role acute injury (AKI) unknown. Here we aimed investigate putative channels AKI. We used Trpc6-/- mice pharmacological blockade (SH045 BI-749327), evaluate short-term AKI outcomes. Here, demonstrate neither Trpc6 deficiency...
Acinetobacter baumannii, associated with nosocomial infections, is considered a significant mortality risk if not adequately addressed.A. baumannii infections typically occur after surgery or trauma.Our patient developed complicated A. meningitis lateral ventriculitis and lumbar abscess post-surgery following fall.The was treated 21-day regimen of intrathecally administered colistin polymyxin B. Following this therapeutic period, the patient's condition improved, leading to successful...
Endothelial dysfunction (ED) comes with age, even without overt vessel damage such as that which occurs in atherosclerosis and diabetic vasculopathy. We hypothesized aging would affect the downstream signalling of endothelial nitric oxide (NO) system vascular smooth muscle (VSM). With this mind, resistance mesenteric arteries were isolated from 13-week (juvenile) 40-week-old (aged) mice tested under isometric conditions using wire myography. Acetylcholine (ACh)-induced relaxation was reduced...
Reduced renal medullary oxygen supply is a key factor in the pathogenesis of acute kidney injury (AKI). As medulla exclusively receives blood through descending vasa recta (DVR), dilating these microvessels after AKI may help renoprotection by restoring flow. We stimulated NO-sGC-cGMP signalling pathway DVR at three different levels before and hypoxia/re-oxygenation (H/R). Rat were isolated perfused under isobaric conditions. The phosphodiesterase 5 (PDE5) inhibitor sildenafil (10-6 mol/L)...
Video-assisted thoracic surgery (VATS) is currently used for the repair of pectus excavatum. Analgesia after can be provided with nerve blocks, intravenous drugs, or neuraxial techniques. Serratus posterior superior intercostal plane block (SPSIPB) a novel interfascial and it performed between serratus muscle muscles at level second third ribs. In this case, we present our successful analgesic experience SPSIPB in patient who underwent minimally invasive excavatum VATS technique.
Currently, the Covid-19 pandemic forces almost every country to take drastic measures stop spread of virus. These include avoidance close contact with other humans, staying at home whenever possible and closure gyms or sport clubs. Now that people are more less bound their home, it is even important stay physically active. The occasional walks between sofa fridge not enough keep your body in shape. But why exercise so there anything one can get most out single training session? Regular...
We encounter multiple cranial, thoracal, abdominal, and extremity lesions caused by traffic accidents fall from a height. Follow-up treatment of these cases in intensive care units (ICUs) are arranged within the discipline approach to case injury. In present case, we deal- ing with 38-year-old female patient who had head trauma minibus. The was presented our ICU tracheal rupture. Youn bak›m unitelerinde birden fazla lezyonun izlem ve tedavisi, bir yaralanma olgusuna yaklafl›m disiplini...
Yüzlerce yıl boyunca yeni ilaçların temelini doğal ürünler ve bunlardan elde edilmiş bileşikler oluşturmuştur. Sekonder metabolitler olarak adlandırılan bu doğada organizmalar tarafından düşmanlarından korunma amacıyla üretilmektedir. Son yıllarda benzer metabolitlerin izole edilmesi ayrıca sentetik üretimin yüksek tarama olanakları sunmasının da etkisiyle ürünlere yönelik ilaç araştırmaları oldukça azalmıştır. Bununla birlikte çeşitli patojenlerin hastanelerde toplumda dirençli suşlar...
The aims of this survey study were to evaluate the contribution YouTube nerve-block learning/education and advantages disadvantages YouTube.A total 24 questions selected for by consensus authors. Information in form web data was obtained through an electronic that distributed via WhatsApp known email addresses phone numbers 300 practitioners (anesthesia residents, anesthesiologists, academicians). There a on survey. first section included 5 collecting demographic data, second part...
We aimed to compare the effects of observation physician (POB) or by adhering protocol-based (PB) weaning methods on total antioxidant capacity (TAC) and oxidative stress (TOS) levels success levels.Our study was conducted patients admitted from emergency department between January 2015 2018 in intensive care unit our hospital. During spontaneous breathing trial (SBT), when one criteria specified developed, SBT terminated previous mechanical ventilator parameters were returned. The patient...