Objective: We report an outbreak of Achromobacter xylosoxidans at a neonatal intensive care unit.We aimed to present clinical, laboratory and treatment data the patients. Materials methods:All consecutive episodes bacteremia due A. our unit, beginning with index case detected November 2009 until cessation in April 2010, were evaluated retrospectively.Results: Thirty-four occurred 22 neonates during 6-month period.Among affected, 90% preterm newborns gestational age 32 weeks or less 60% had...

Introduction: We aimed to determine the incidence, etiology, risk factors and outcome of bacterial meningitis in neonates. Methodology: Neonates who developed between 2003 2010 a tertiary hospital Turkey were included study. Patients born our defined as Group 1 patients referred from other centres 2. with evidence congenital infections or central nervous system malformations excluded. Demographic features, delivery type, time onset meningitis, co-morbidities, clinical blood cerebrospinal...

Akkoc T, Aydogan M, Yildiz A, Karakoc-Aydiner E, Eifan Keles S, Akin Kavuncuoglu Bahceciler NN, Barlan IB. Neonatal BCG vaccination induces IL-10 production by CD4+ CD25+ T cells.Pediatr Allergy Immunol 2010: 21: 1059–1063.© 2010 John Wiley & Sons A/S To determine the optimal time of Bacillus Calmette–Guerin (BCG) for induction Th1 immunity, we measured interferon (IFN)-γ and interleukin (IL)-10 secretion in purified protein derivative (PPD)-stimulated peripheral blood mononuclear cell...

Cardiac rhabdomyoma often shows spontaneous regression and usually requires only close follow-up. However, patients with symptomatic inoperable rhabdomyomas may be candidates for everolimus treatment. Our patient had multiple cardiac causing serious left ventricle outflow-tract obstruction that showed a dramatic reduction in the size after therapy, mammalian target of rapamycin (mTOR) inhibitor. After discontinuation an increase diameter masses occurred was restarted. 6 months treatment,...

Neonatal sepsis remains a major cause of morbidity and mortality in newborns. The chemokine CXCL12 its receptor CXCR4 are now known to play an important role inflammatory states. However, it is unclear how chemokines respond late-onset neonatal sepsis.Patients were classified into the groups septic non-septic ones. Samples venous blood obtained from all newborns at beginning within 48-72 h after initiation treatment. Serum levels measured.Concentrations IL-6, time diagnosis significantly...

Very low birth weight preterm infants are under significant risk of neurologic, developmental, and somatic problems. In this study, 90 born with a <1500 g and/or gestational age <32 weeks were evaluated after the first year elementary school to assess neurodevelopment. The Wechsler Intelligence Scale for Children-Revised (WISC-R) test, Pediatric Symptom Checklist, Parent Evaluation Developmental Status performed. Mental retardation, cerebral palsy, blindness, epilepsy, posthemorrhagic...

The aim of this study was to compare perinatal, neonatal characteristics and neurodevelopmental prognosis preterm infants born after in vitro fertilization (IVF) spontaneous multiple pregnancy, evaluate the factors affecting outcome at 24-36 months.A total 125 infants, 65 from 60 IVF pregnancy were evaluated terms age months. Mean maternal age, chronic disease, birthweight, gestational week, gender, APGAR score, intensive care unit admission, presence congenital anomalies, referral follow...

The aim of this study was to determine the distribution cases associated with congenital abnormalities during following three periods: pregnancy, birth, and neonatal period. This a retrospective between 2002 2006. All abnormal pregnancies, elective terminations stillbirths, births managed in Neonatology Unit were classified based on above scheme. During 5-year period, 1906 recruited, as follows: 640 prenatally detected terminated cases, most related central nervous system, chromosomes,...

<b>Objective</b> Systemic fungal infections are major causes of morbidity and mortality, associated with significant neurodevelopmental impairment in premature infants. Our objective was to evaluate the efficacy fluconazole prophylaxis prevention systemic among preterm <b>Study Design</b> This observational pre-post cohort study performed infants a birth weight < 1,000 g who were given prophylactic starting on first postnatal day at dose 3 mg/kg twice week. These compared not prophylaxis....

Aim: To investigate the effect of intravenous frusemide on course transient tachypnoea newborn (TTN). Methods: Fifty term infant with TTN were randomised at time diagnosis to receive either 2 mg/kg or saline placebo. Outcomes assessed included duration supplemental oxygen requirement, period tachypnoea, discharge from hospital and weight loss in first 24 h life before discharge. Results: The two groups similar respect sex, birthweight, mode delivery age presentation . study group lost...

We examined the association of active ghrelin levels with birth weight, sex, and gestational age (GA) in small for GA (SGA) appropriate (AGA) preterm infants.Active were measured by ELISA method during first five postnatal days 38 SGA infants 32 AGA controls.Active significantly higher than controls (P < 0.01). Active preterms weight <1500 g statistically those over 1500 g. ≤ 34 weeks similar to weeks. A negative correlation was detected between (r = -0.561, P 0.0001) as well -0.449,...

The aim of this study was to evaluate physical growth very low birth weight (VLBW) preterm babies at a mean age three years and investigate the factors which affected growth.The including maternal problems, prenatal early neonatal nutrition, familial socioeconomical status presence chronic disease catch-up in terms height VLBW infants followed up intensive care unit (NICU) our hospital were examined. target formula used assessment growht contribution genetic properties investigated. points...

The mortality and morbidity of fetal aortic stenosis (AS) depend on the degree hemodynamic effects stenosis, left ventricular (LV) adaptation, development function during life. In case critical AS, hydrops death in utero are well recognized entities. A 23-week gestation fetus was diagnosed with severe cardiomegaly, a dilated LV very poor contractility, mitral regurgitation. There reversal flow arch through ductus arteriosis reversed a-wave venosus Doppler examination. had ascites, massive...

Approximately 10% of neonates with Down syndrome may develop a form megakaryoblastic leukemia that usually disappear spontaneously during the first months life. Although it seems to have benign course, also be lethal and severe in some cases, especially hydrops and/or cardiopulmonary failure. Herein, we report male infant who was admitted respiratory distress due pericardial effusion leading tamponade 2 weeks Pericardiosentesis tube replacement combination steroid therapy performed. He...

Familial Mediterranean Fever is an autosomal recessive disease. Major symptoms of disease are recurrent fever accompanied by serositis attacks. The usually diagnosed before 20 years age. Symptoms related to FMF noted when children become more verbal, after 2 In this case report, the youngest patient with diagnosis presented. She was consulted pediatric rheumatology for high acute phase response and fever. It learned that her mother had swelling ankle joints. Mutation analysis performed two...

In this study, we aimed to investigate the utility of tubular reabsorption phosphorus in diagnosis osteopenia prematurity addition biochemical markers.Premature babies with a gestational age ≤32 weeks and/or birth weight ≤1 500 g who were hospitalized neonatal intensive care unit between June 2009 and March 2011 included study. These evaluated at 40th week serum calcium, phosphorus, alkaline phosphatase, urea, creatinine, urinary calcium levels measured was determined. The subjects had bone...

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Acute scrotal abscess is a rare condition in neonates. Most of these abscesses were reported to be unilateral and caused by Staphylococcus Salmonella spp. Herein, we report bilateral preterm infant Candida albicans was isolated from the fluid culture. To our knowledge, this first C. albicans. Therefore, organism must suspected differential diagnosis acute neonates, especially infants.

The cause of meconium stained amniotic fluid in term healthy pregnancies is not clearly understood yet. aim this study was to investigate the placental ultrastructural changes and apoptosis complicated with fluid.The group composed mothers (n: 13) their term, appropriate for gestational age newborns but without aspiration syndrome. control consisted 24) babies. We studied by transmission electron microscopy TUNEL method.The incidence method significantly higher compared group. Transmission...