A5049640288- Pesticide Residue Analysis and Safety
- Pharmacological Effects and Assays
- Antibiotics Pharmacokinetics and Efficacy
- Analytical chemistry methods development
- Pharmaceutical and Antibiotic Environmental Impacts
- Environmental Toxicology and Ecotoxicology
- Analytical Chemistry and Chromatography
- Antibiotic Resistance in Bacteria
- Agricultural safety and regulations
- Vibrio bacteria research studies
- Parasite Biology and Host Interactions
- Helminth infection and control
- Pesticide Exposure and Toxicity
- Meat and Animal Product Quality
- Gut microbiota and health
- Bioactive natural compounds
- Natural product bioactivities and synthesis
- Parasites and Host Interactions
- NF-κB Signaling Pathways
- Analytical Methods in Pharmaceuticals
- Pharmacology and Obesity Treatment
- Bacterial Identification and Susceptibility Testing
National Institute of Food and Drug Safety Evaluation
2022-2024
Ministry of Food and Drug Safety
2022-2024
Kangwon National University
2013-2024
Dankook University
2024
Aromadendrin, a flavonol, has been reported to possess variety of pharmacological activities such as anti-inflammatory, antioxidant, and anti-diabetic properties. However, the underlying mechanism by which aromadendrin exerts its biological activity not extensively demonstrated. The objective this study is elucidate anti-inflammatory aromadedrin in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. Aromadendrin significantly suppressed LPS-induced excessive production...
Abstract The widespread use of sulfonamides can result in the residue foods animal origin that are major concerns consumers and regulatory bodies due to their adverse reaction such as development antibiotic resistance. A rapid efficient multi-residue analytical method was developed screen confirm 31 livestock samples a single run, using ultra-high-performance liquid chromatography combined with comprehensive mass spectrometric approaches. In this study, novel sample preparation procedure...
Abstract Fish are susceptible to blood-sucking parasite infections, which cause severe anemia, dyspnea, and ultimately death. However, veterinary drugs available for fish treat such infectious diseases lacking; thus, livestock have been repurposed as aquatic animal drugs. Febantel (FBT) fenbendazole (FBZ) representative antiparasitic agents cattle, swine, poultry, considered suitable Therefore, we investigated the safety efficacy of FBT FBZ in performed a risk assessment determine maximum...
Flunixin is a veterinary nonsteroidal anti-inflammatory agent whose residues have been investigated in their original form within tissues such as muscle and liver. However, flunixin remains milk metabolite, 5-hydroxy has used the primary marker for its surveillance. This study aimed to develop quantitative method detecting strengthen monitoring system by applying other livestock fishery products. Two different methods were compared, target compounds extracted from using an organic solvent,...
Multi-class, Multi-residue Analysis of 59 Veterinary Drugs in Livestock Products for Screening and Quantification Using Liquid Chromatography-tandem Mass Spectrometry-LC-MS/MS,Livestock products,Multi-class analysis,Veterinary drug
An accurate and easy-to-use analytical method for determining isocycloseram its metabolites (SYN549431 SYN548569) residue is necessary in various food matrixes.Additionally, this should satisfy domestic international guidelines (Ministry of Food Drug Safety Codex Alimentarius Commission CAC/ GL 40).Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) was used to determine the foods.To metabolites, a sample extracted with 20 mL 0.1% formic acid acetonitrile, 4 g magnesium sulfate...
As veterinary drugs available for fish is very restricted, there growing trials repurposing livestock as aquatic animal drugs. Tylosin one of the most effective antibiotics to treat bacterial infections approved livestock, and would be used in fish. Hence, we investigated toxicological microbiological aspects tylosin establish health-based guidance value (HBGV) maximum residue limit (MRL) fishes, reevaluated acceptable daily intake (mADI) based on updated relevant data international...
Establishment of Acceptable Daily Intakes (ADIs) and Risk Assessment for Ephedrine, Menichlopholan, Anacolin, Etisazole Hydrochloride-Anacolin,Ephedrine,Etisazole hydrochloride,Menichlopholan,Risk assessment
Abstract In this study, an analysis method was established for the quantification of residues halquinol and its metabolites in livestock fishery products using liquid chromatography–tandem mass spectrometry (LC–MS/MS). We selected beef, pork (muscle fat), chicken, egg, milk, flat fish, eel, shrimp as target samples validation owing to them being typical products. Validation developed performed (LC–MS/MS) at three concentration levels (0.5, 1, 2 × maximum residue limits) following Codex...
BACKGROUND:The β-agonists known as phenyl ethanolamine derivatives have a conjugated aromatic ring with amino group.They are used tocolytic agents and bronchodilator to human animal generally, some of them growth promoters livestock.METHODS AND RESULTS: in samples were extracted by 0.4 N perchloric acid ethyl acetate.The target compounds analyzed liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS/MS).Validation method was performed according CODEX guidelines...