A5066441854- Vector-borne infectious diseases
- Vibrio bacteria research studies
- Mosquito-borne diseases and control
- Legionella and Acanthamoeba research
- Plant Parasitism and Resistance
- Clostridium difficile and Clostridium perfringens research
- Toxoplasma gondii Research Studies
- Streptococcal Infections and Treatments
Université de Montpellier
2021-2024
Centre National de la Recherche Scientifique
2021-2024
Institut de Recherche en Infectiologie de Montpellier
2021-2024
Intracellular bacterial pathogens divert multiple cellular pathways to establish their niche and persist inside host. Coxiella burnetii , the causative agent of Q fever, secretes effector proteins via its Type 4 secretion system generate a -containing vacuole (CCV). Manipulation lipid protein trafficking by these effectors is essential for replication virulence. Here, we have characterized composition CCVs found that Vice interacts with phosphoinositides membranes enriched in...
Ezrin protein is involved in the interaction of actin cytoskeleton with membrane receptors such as CD44. It regulates plasma dynamics and intracellular signaling. Coxiella burnetii, etiologic agent Q fever, internalized into host cell through a poorly characterized molecular mechanism. Here we analyzed role ezrin CD44 C. burnetii internalization by HeLa cells. The knockdown inhibited bacterial uptake. Interestingly, at early stages internalization, was recruited to fraction phosphorylated....
Abstract Intracellular bacterial pathogens divert multiple cellular pathways to establish their niche and persist inside host. Coxiella burnetii , the causative agent of Q fever, secretes effector proteins via its Type 4 secretion system generate a -containing vacuole (CCV). Manipulation lipid protein trafficking by these effectors is essential for replication virulence. Here, we have characterized composition CCVs discovered that Vice interacts with phosphoinositides membranes enriched in...