- Vector-borne infectious diseases
- Toxoplasma gondii Research Studies
- Clostridium difficile and Clostridium perfringens research
- Fatty Acid Research and Health
- Streptococcal Infections and Treatments
- COVID-19 Clinical Research Studies
- Autophagy in Disease and Therapy
- Toxin Mechanisms and Immunotoxins
- Antioxidant Activity and Oxidative Stress
- Yersinia bacterium, plague, ectoparasites research
- Brucella: diagnosis, epidemiology, treatment
- Influenza Virus Research Studies
- Nanoplatforms for cancer theranostics
- Calpain Protease Function and Regulation
- Poxvirus research and outbreaks
- Respiratory viral infections research
- Bioactive Compounds and Antitumor Agents
- T-cell and Retrovirus Studies
- Botulinum Toxin and Related Neurological Disorders
- Vector-Borne Animal Diseases
- Gut microbiota and health
- Edible Oils Quality and Analysis
- COVID-19 Pandemic Impacts
- Nutritional Studies and Diet
- Oral microbiology and periodontitis research
Universidad de Málaga
2023-2024
Centro de Investigación Biomédica en Red
2024
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2023-2024
Instituto de Investigación Biomédica de Málaga
2023-2024
Hospital Regional Universitario de Málaga
2023-2024
Universidade Federal de Mato Grosso do Sul
2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2015-2022
Universidad Nacional de Cuyo
2015-2022
Instituto de Histología y Embriología de Mendoza
2015-2022
Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias
2010
Oleocanthal and oleacein are olive oil phenolic compounds with well known anti-inflammatory anti-oxidant properties. The main evidence, however, is provided by experimental studies. Few human studies have examined the health benefits of oils rich in these biophenols. Our aim was to assess properties oleocanthal extra virgin (EVOO), compared those common (OO), people prediabetes obesity.Randomised, double-blind, crossover trial done aged 40-65 years obesity (BMI 30-40 kg/m2) (HbA1c 5.7-6.4%)....
The GTPases belonging to the Rho family control actin cytoskeleton rearrangements needed for particle internalization during phagocytosis. ROCK and mDia1 are downstream effectors of RhoA, a GTPase involved in that process. Coxiella burnetii, etiologic agent Q fever, is internalized by host´s cells an actin-dependent manner. Nevertheless, molecular mechanism this process has been poorly characterized. This work analyzes role different some C. burnetii phagocytic non-phagocytic cells. into...
The objective of this study was to evaluate in native cattle the use an vitro derived attenuated live vaccine (Babesia bovis–Babesia bigemina). Three commercial farms located a tropical region Chiapas State, Mexico were included. For each ranch, 40 animals selected as negative Babesia spp. by using immunofluorescent antibody test (IFAT) and PCR. Animals distributed four groups with 10 each: (i) <9 months, (ii) 9–18, (iii) 18–36 (iv) >36 months old. From group, two subgroups formed five each;...
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has represented a great threat to global health, being more severe than that other coronaviruses such as acute respiratory syndrome coronavirus (SARS-CoV) and Middle East (MERS-CoV).
The induction of macrophage death is regarded as a potential mechanism by which components secreted Clostridium septicum are used to evade the innate immune response and cause tissue damage. This study aimed determine effect partially purified fractions extracellular proteins C. on mouse peritoneal macrophages. Elicited macrophages were incubated with into culture medium. After incubation, we found that protein fraction molecular weight &ge; 100 kDa caused significant cell in...
Ezrin protein is involved in the interaction of actin cytoskeleton with membrane receptors such as CD44. It regulates plasma dynamics and intracellular signaling. Coxiella burnetii, etiologic agent Q fever, internalized into host cell through a poorly characterized molecular mechanism. Here we analyzed role ezrin CD44 C. burnetii internalization by HeLa cells. The knockdown inhibited bacterial uptake. Interestingly, at early stages internalization, was recruited to fraction phosphorylated....
Microtubules (Mts) are dynamic cytoskeleton structures that play a key role in vesicular transport. The Mts-mediated transport depends on motor proteins named kinesins and the dynein/dynactin complex. Rab7 adapter protein FYCO1 controls anterograde of endocytic compartments through interaction with kinesin KIF5. its partner RILP induce recruitment to late endosomes regulating retrograde perinuclear area fuse lysosomes. endosomal-lysosomal fusion is regulated by HOPS complex GTPase Arl8....
The induction of macrophage death is regarded as a potential mechanism by which components secreted Clostridium septicum are used to evade the innate immune response and cause tissue damage. This study aimed determine effect partially purified fractions extracellular proteins C. on mouse peritoneal macrophages. Elicited macrophages were incubated with into culture medium. After incubation, we found that protein fraction molecular weight ≥ 100 kDa caused significant cell in macrophages,...
Antimicrobial photodynamic inactivation (aPDI) offers a promising alternative to combat drug-resistant bacteria. This study explores the potential of lapachol, natural naphthoquinone derived from Tabebuia avellanedae, as photosensitizer (PS) for aPDI. Lapachol’s photosensitizing properties were evaluated using Staphylococcus aureus and Escherichia coli strains under blue LED light (450 nm). UV-vis spectroscopy confirmed lapachol’s absorption peak at 482 nm, aligning with effective excitation...
Damage to intestinal epithelial cells is present in obesity and other diseases because of inflammatory oxidative processes. This damage compromises the gastrointestinal barrier, killing enterocytes, altering permeability, eliciting abnormal immune responses that promote chronic inflammation. Recent evidence shows spirulina a potent natural agent with antioxidant anti-inflammatory properties. Objectives: study was conducted evaluate effect aqueous extract (SPAE) on alterations epithelium...
Abstract Oleocanthal and oleacein are olive oil phenolic compounds with well known anti-inflammatory anti-oxidant properties. The main evidence, however, is provided by experimental studies. Few human clinical trials have examined the health benefits of oils rich in these polyphenols. Our aim was to assess properties oleocanthal extra virgin (EVOO), compared those common (OO), people prediabetes obesity. This a randomised, double-blind, crossover trial done aged 40-65 years obesity (BMI...
Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding C. invasion its survival i... | Find, read cite all research you need on Tech Science Press