Shared links between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) have been well-known. A high concentration of advanced glycation end products (AGEs) has reported to contribute impaired mobility in patients with AD, but there is limited understanding regarding the longitudinal impact AGEs on cognitive performance.This study aims explore whether concentrations mediate clinical progression performance AD T2DM.Twenty-five aged 79.0±5.8 years who were diagnosed probable a...

Rates of return to work (RTW) after an occupational injury vary considerably according a range factors. Limited studies have been conducted on the specific correlation between RTW and functional assessments, including activities daily living (ADL) instrumental (IADL). This prospective cohort study aims determine if relationship exists ADL/IADL among injured workers in Taiwan. We recruited 162 who reported work-related injuries from January 2023 May 2024. The assessment ADL was evaluated...

Abstract Objective: This article aims to explore the correlation between well-being and burnout analyze other potential predictors of burnout. Methods: The analyses included 242 Taiwanese workers with a balanced gender ratio. Our study used Chinese version Workplace PERMA (Positive Emotion, Engagement, Relationship, Meaning, Accomplishment) -Profiler for assessment Copenhagen Burnout Inventory (CBI) assess participants' condition. results questionnaire were analyzed their correlations using...

Objective: The aim of our study was to introduce a Mandarin Chinese version the oral frailty assessment and explore relationship between sarcopenia. A total 409 elders (171 male, 238 female) participated in surveys using Oral Frailty Index-8 (OFI-8) Kaohsiung, Taiwan. Method: translation OFI-8 adhered Consensus-based Standards for Selection Health Measurement Instruments (COSMIN) reporting guidelines. eight-item questionnaire assessed tooth status, function, other subjective measures....

Western theorists have generally construed reward allocation as mainly a rational action by the notion that decision‐making is based solely on people’s justice concern. We argued allocation, social act taking place in specific social‐situational context, influenced both some interactive factors such relationship and interactions between participants, pervasive norms governing conduct particular society. This study aimed at examining influence of two factors, guanxi (equivalent to...

The links of air pollutants to health hazards have been revealed in literature and inflammation responses might play key roles the processes diseases. WBC count is one indexes inflammation, however l iterature reveals inconsistent opinions on relationship between counts exposure pollutants. goal this population-based observational study was examine associations multiple counts. This recruited community subjects from Kaohsiung city. count, demographic hazard habit data were collected....

This research aimed to approach relationships between metal mixture in blood and kidney function, tumor necrosis factor alpha (TNF-α) by machine learning. Metals levels were measured Inductively Couple Plasma Mass Spectrometry from 421 participants. We applied K Nearest Neighbor (KNN), Naive Bayes classifier (NB), Support Vector Machines (SVM), random forest (RF), Gradient Boosting Decision Tree (GBDT), Categorical boosting (CatBoost), eXtreme (XGBoost), Whale Optimization-based XGBoost...

Abstract Background Well-being is an important issue in workplace. One of these assessment tools well-being, Workplace PERMA Profiler, based on Seligman’s five dimensions well-being. Prolonged fatigue may last for a long time, leading great impact both employees and enterprises. However, rare studies about the association between well-being had been investigated. Our aim to establish Chinese version discovery workplace fatigue. Methods The was established according International Society...

The association between metal mixtures and kidney function has been reported. However, reports on the mechanism of toxicity were limited. Oxidative stress was reported as a possible cause. This study aimed to determine metals, such arsenic (As), cadmium (Cd), cobalt (Co), copper (Cu), lead (Pb), selenium (Se), zinc (Zn), explore mediating role tumor necrosis factor alpha (TNF-α) function. In this study, we recruited 421 adults from health examination. concentration blood metals analyzed...

Readers are invited to submit letters for publication in this department. Submit online at http://joem.edmgr.com. Choose "Submit New Manuscript." A signed copyright assignment and financial disclosure form must be submitted with the letter. Form available www.joem.org under Author Reviewer information. To Editor: The number of small medium-sized enterprises (SME) far exceeds that large companies, much more people employed.1 SMEs flexible adapting some economic changes, however, due smaller...

Exposure to heavy metals could lead adverse health effects by oxidative reactions or inflammation. Some essential elements are known as reactors of anti-inflammatory enzymes coenzymes. The relationship between tumor necrosis factor alpha (TNF-α) and metal exposures was reported. However, the interaction toxic in inflammatory response remains unclear. This study aimed explore association arsenic (As), cadmium (Cd), (Pb), cobalt (Co), copper (Cu), selenium (Se), zinc (Zn) blood TNF-α well...

Background Physical frailty is an important issue in aging societies. Three models of physical assessment, the 5-Item fatigue, resistance, ambulation, illness and loss weight (FRAIL); Cardiovascular Health Study (CHS); Osteoporotic Fractures (SOF) indices, have been regularly used clinical research studies. However, no previous studies investigated predictive ability machine learning (ML) for assessment. The aim was to use two ML algorithms, random forest (RF) extreme gradient boosting...

Workers in high-temperature workplaces with inadequate water supply may exhibit symptoms of chronic dehydration and have increased risk nephrolithiasis. The aim this study was to investigate the radiolucent stone formation among workers a workplace related factors associated condition. We collected data from 1681 steel factory Southern Taiwan who underwent regular health examinations. Radiolucent stones were defined as positive findings on ultrasound negative radiographic images. prevalences...

Air pollutants are substances in the air that have harmful effects on humans and ecological environment. Although slight elevations carcinoembryonic antigen (CEA) commonly observed apparently healthy persons, potential associations between CEA levels chronic low-grade inflammation induced by pollution yet to be documented. We conducted a community-based cross-sectional study estimate association short-term exposure ambient CEA. A total of 9728 participants from health examinations were...

Chronic exposure to lead is neurotoxic the human peripheral sensory system. Variant vitamin D receptor (VDR) genes and polymorphisms of metallothioneins (MTs) are associated with different outcomes following toxicity. However, no evidence a relationship between neurotoxicity has previously been presented. In this study, we investigated VDR, MT1A, MT2A toxicity chronic occupational exposure. We measured vibration perception thresholds (VPT) current (CPT) in 181 workers annually for five...

Background: Lead inhibits the enzymes in heme biosynthesis, mainly reducing δ-aminolevulinic acid dehydratase (ALAD) activity, which could be an available biomarker. The aim of this study was to detect threshold activity reduced by lead exposure. Methods: We collected data on 121 workers and 117 non-exposed when annual health examinations were performed. ALAD determined standardized method European Community. G177C (rs1800435) genotyping conducted using polymerase chain reaction restricted...

Ambient temperature change is one of the risk factors human health. Moreover, links between white blood cell counts (WBC) and diseases have been revealed in literature. Still, we do not know any association ambient WBC counts. The aim our study to investigate relationship We conducted this two-year population-based observational Kaohsiung city, recruiting voluntary community participants. Total differential counts, demographic data health hazard habits were collected matched with...