A5086240830- Cardiomyopathy and Myosin Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Function and Risk Factors
- Parathyroid Disorders and Treatments
- Dermatological and COVID-19 studies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Risk Factors
- Parvovirus B19 Infection Studies
- COVID-19 Clinical Research Studies
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- Enhanced Recovery After Surgery
- Cardiovascular Effects of Exercise
- Lung Cancer Research Studies
- Health disparities and outcomes
- Bartonella species infections research
- Healthcare Systems and Public Health
- Cardiac Structural Anomalies and Repair
- Autoimmune Bullous Skin Diseases
- Studies on Chitinases and Chitosanases
- Clinical Nutrition and Gastroenterology
- Streptococcal Infections and Treatments
- Williams Syndrome Research
Assistance Publique – Hôpitaux de Paris
2019-2024
Université de Rouen Normandie
2024
Hôpitaux Universitaires Henri-Mondor
2022-2024
Aix-Marseille Université
2023
Université de Versailles Saint-Quentin-en-Yvelines
2020-2022
Inserm
2018-2022
Institut Mondor de Recherche Biomédicale
2022
Université Paris-Est Créteil
2022
Hôpital Ambroise-Paré
2018-2021
Laboratoire National de Référence
2021
Data whether the COVID-19 outbreak impacts acute coronary syndromes (ACS) admissions and time required to reverse downward curve are scarce. We included all consecutive patients referred for an ACS who underwent PCI from February 17, 2020 April 26, in a high-volume care unit. compared number of same period 2018 2019. Predictors adverse outcome ST-elevation myocardial infarction (STEMI) were recorded: symptom-onset-to-first medical contact (FMC), FMC-to-sheath insertion times. During studied...
Background Laser Doppler flowmetry (LDF) can measure blood flow in the hepatic microcirculation. Adequate graft perfusion is essential to outcome of organ transplantation and has not previously been measured during operation liver transplant recipients. Methods LDF was carried out 22 human grafts after restoring portal vein artery inflow. readings were validated against with an electromagnetic flowmeter. Intraoperative haemodynamics donor parameters known influence function correlated LDF....
Background. We assessed the usefulness of a longitudinal strain adjusted to regional thickness in hypertrophic cardiomyopathy (HCM). Indeed, with conventional software, width region interest (ROI) is same over entire myocardial wall, wherein software analyzes only partially left ventricular (LV) segments. Methods. included 110 patients: 55 patients HCM (HCM group) and healthy subjects (age- sex-matched control group). The global (GLS) for each 17 segments was calculated standard (for two...
Transthyretin cardiac amyloidosis (ATTR-CM) may be an underestimated cause of heart failure among geriatric patients and represent a unique phenotype prognostic profile.
Background and aims Self-reported questionnaires are useful for estimating the health-related quality of life (HR-QoL), impact interventions, prognosis. To our knowledge, no HR-QoL questionnaire has been developed cardiac amyloidosis (CA). This study aimed to validate Amylo-AFFECT-QOL assess its prognostic value in CA. Methods A self-reported questionnaire, “Amylo-AFFECT” had designed validated CA symptoms evaluation screening by physicians. It was adapted here (Amylo-AFFECT-QOL) theoretical...
Data regarding renal involvement in patients with hereditary transthyretin (ATTRv) amyloidosis are scarce and the natural course of chronic kidney disease (CKD) this population remains unclear. This observational study, including adult diagnosed ATTRv at French Reference Centre for Cardiac Amyloidosis, investigated function outcome its determinants. Multivariable logistic regression models identified factors associated CKD baseline. Determinants change estimated glomerular filtration rate...
Abstract Background For assessing right ventricular function in pulmonary hypertension (PH), the optimal approach is through use of load-independent parameters. While pressure-volume (PV) loops are not feasible clinical settings, maximum velocity contractile element under no load, known as Vmax, serves an alternative measure that could be derived only from right-heart catheterization (RHC). Objectives To determine Vmax patients undergoing RHC and to evaluate its correlation with...
Abstract Background Diastolic dysfunction in hypertrophic cardiomyopathy (HCM) is common, but its assessment difficult using conventional echocardiography. Aims To assess left atrial (LA) function HCM by longitudinal strain and determine role understanding of symptoms. Methods We studied 144 patients divided into 3 age‐ sex‐matched groups: 48 consecutive with HCM, control subjects, athlete subjects. assessed LA echocardiographic parameters (early‐diastolic during reservoir phase [LASr];...
<h3>Introduction</h3> The use of NHBD donor grafts for liver transplantation (LT) is increasing. Large series suggest that patient outcomes are equivalent to heart beating (HBD) graft recipients but there currently scarce literature on the impact increasing perioperative resource utilisation. <h3>Methods</h3> We analysed patients undergoing NHDB LT in our centre over a 2-year period and compared variables similar number HBD (matched age, disease severity indication) determine if livers...
Abstract Background In hypertrophic cardiomyopathy (HCM), longitudinal strain analysis allows to early detect left ventricular (LV) contraction abnormalities despite preserved LV ejection fraction. current software, the width of region interest (ROI) is same over entire myocardial wall, and might analyze partially segments. Purpose The aim this study evaluate a novel software for with an adjustable ROI according each segment thickness. Methods We included 110 patients: 55 patients HCM (HCM...
Abstract Introduction Immune therapy is a new option that has revolutionized cancer therapy. checkpoint inhibitors target mostly either PD-1 (Pembrolizumab, Nivolumab) or PD-L1 (Durvalumab). Immune-related cardiotoxic side effects, among them, tamponade, initially thought to be rare, seem increasingly cited in the literature. Moreover, tobacco smoking linked 80% of lung cancers. Smoking during may influence on radiotherapy and chemotherapy outcomes but little known immunotherapy. Purpose We...