A5001564881- Vascular Malformations and Hemangiomas
- Genetic and rare skin diseases.
- Dermatology and Skin Diseases
- Vascular Malformations Diagnosis and Treatment
- Cancer and Skin Lesions
- Vascular Tumors and Angiosarcomas
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Autoimmune and Inflammatory Disorders
- Psoriasis: Treatment and Pathogenesis
- Central Venous Catheters and Hemodialysis
- Tumors and Oncological Cases
- Dermatological and COVID-19 studies
- Dermatological diseases and infestations
- Melanoma and MAPK Pathways
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Hidradenitis Suppurativa and Treatments
- Acne and Rosacea Treatments and Effects
- Dermatologic Treatments and Research
- Vascular anomalies and interventions
- Vector-borne infectious diseases
- Dermatological and Skeletal Disorders
- melanin and skin pigmentation
Inserm
2019-2025
Université de Tours
2017-2025
Centre Hospitalier Universitaire de Tours
2017-2025
University of Nottingham
2023-2025
Sciences, Philosophie, Histoire
2019-2025
Nantes Université
2019-2024
Thion Medical (France)
2023-2024
Clinical Investigation Center Plurithematic Tours
2019-2023
Centre Hospitalier Régional Universitaire de Brest
2023
Société Française de Cardiologie
2023
<h3>Importance</h3> Sirolimus is increasingly being used to treat various vascular anomalies, although evidence of its efficacy lacking. <h3>Objective</h3> To assess the and safety sirolimus for children with slow-flow malformations better delineate indications treatment. <h3>Design, Setting Participants</h3> This multicenter, open-label, observational-phase randomized clinical trial included 59 aged 6 18 years a malformation who were recruited between September 28, 2015, March 22, 2018, in...
Slow-flow superficial vascular malformations (VMs) are rare congenital anomalies that can be responsible for pain and functional impairment. Currently, we have no guidelines their management, which involve physical bandages, sclerotherapy, surgery, anti-inflammatory or anti-coagulation drugs treatment. The natural history is progressive worsening. Mammalian target of rapamycin (mTOR) a serine/threonine kinase acts as master switch in cell proliferation, apoptosis, metabolism...
Abstract Background Cutaneous microcystic lymphatic malformations (CMLMs) are rare conditions in children and adults. They present as clusters of vesicles full lymph blood to various extents, inducing maceration, esthetic impairment, pain, impaired quality life. The treatment is challenging. Sirolimus an inhibitor mammalian target rapamycin (mTOR) involved angio-lymphangiogenesis. Topical sirolimus has recently been reported effective a few reports patients with CMLMs. objective compare the...
New highly effective drugs for moderate-to-severe cutaneous psoriasis are regularly marketed, and the hierarchy of treatments thus requires frequent review.
Abstract Predatory journals, first recognized in the early 2000s, are fraudulent publications characterized by aggressive marketing solicitations and deviation from best publishing practices. These journals claim to be legitimate scholarly publications, accept articles with no or poor peer review processes quality checks, rapid publication on payment authors. They a global threat as they dishonest, lack transparency seek only financial gain. More recently, predatory conferences have emerged...
Abstract Aim To evaluate the knowledge, practices and self‐confidence of community pharmacists, pharmacy technicians students about infantile haemangioma (IH) propranolol treatment. Methods A national survey was conducted in France from May 2022 to October 2022. 42‐item online questionnaire used assess pharmacists' knowledge epidemiology, clinical features management IH Results The included 255 participants. mean age 34.9 years (±9.0); 225 (88%) were women. In all, 193 (76%) practised urban...
Abstract is missing (Quiz)
Although superpotent topical corticosteroids are the first-line treatment for oral erosive lichen planus (OELP), rapamycin was found efficient in a previous case series.To compare efficacy and safety of betamethasone dipropionate ointment OELP randomized, double-blind trial.Patients were randomized to receive with 0.05% Orabase® or solution (1 mg/mL) on lesions twice daily 3 months, followed by months observation. The primary outcome clinical remission after treatment. Secondary outcomes 1 2...
Abstract Background Lingual microcystic lymphatic malformations (LMLMs) are rare congenital vascular presenting as clusters of cysts filled with lymph fluid or blood. Even small well-limited lesions can be responsible for a heavy burden, inducing pain, aesthetic prejudice, oozing, bleeding, infections. The natural history LMLMs is progressive worsening punctuated by acute flares. Therapeutic options include surgery, laser excision, and radiofrequency ablation but all potentially detrimental...
Abstract Background Health care transition (i.e., from pediatric to adult care) is challenging in chronic conditions but has been poorly studied rare skin diseases. We investigated the proportion of lost follow-up among patients with superficial vascular malformations after health transition. also collected patients’ opinions. This prospective, multicenter, cross-sectional study was performed at 7 French hospitals. included aged 19–25 years, who were followed for a malformation before age...
Patients with an inherited autosomal-dominant disorder, capillary malformation-arteriovenous malformation (CM-AVM), frequently have mutations in Ras P21 protein activator 1 (RASA1). The aims of this study were to determine the prevalence germline RASA1 variants a French multicentre national cohort children, age range 2-12 years, sporadic occurrence (CM) legs, whatever associated abnormalities, and identify genotype-phenotype correlates. DNA was extracted from leukocytes blood samples,...