- Cardiovascular Health and Disease Prevention
- Astrophysics and Cosmic Phenomena
- Cardiovascular Function and Risk Factors
- Astronomical Observations and Instrumentation
- Stellar, planetary, and galactic studies
- Glycosylation and Glycoproteins Research
- Gamma-ray bursts and supernovae
- Medical Imaging and Pathology Studies
- Astrophysical Phenomena and Observations
- Cardiovascular Disease and Adiposity
- Dark Matter and Cosmic Phenomena
- Radio Astronomy Observations and Technology
- Advanced MRI Techniques and Applications
- Astronomy and Astrophysical Research
- Astrophysics and Star Formation Studies
- Pulmonary Hypertension Research and Treatments
- Advanced Drug Delivery Systems
- Monoclonal and Polyclonal Antibodies Research
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Advancements in Transdermal Drug Delivery
- Infrared Target Detection Methodologies
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Calibration and Measurement Techniques
Toho University
2014-2024
Toho University Medical Center Sakura Hospital
2016-2024
Jikei University School of Medicine
1993-2023
Tokushima University
2011-2022
Juntendo University Hospital
2013-2022
Nagoya University
2008-2021
Juntendo University
2012-2021
Muroran Institute of Technology
2021
Higashi Osaka City General Hospital
2021
Cell Signaling Technology (United States)
2012-2016
We present time-resolved broad-band observations of the quasar 3C 279 obtained from multi-wavelength campaigns conducted during first two years Fermi Gamma-ray Space Telescope mission. While investigating previously reported gamma-ray/optical flare accompanied by a change in optical polarization, we found that emission appears delayed with respect to gamma-ray about 10 days. X-ray reveal pair `isolated' flares separated ~90 days, only weak counterparts. The spectral structure measured...
An overview of the current status 8.2 m Subaru Telescope constructed and operated at Mauna Kea, Hawaii, by National Astronomical Observatory Japan is presented. The basic design concept verified performance telescope system are described. Also given instrument package offered to astronomical community, operation, some future plans. reported in a number SPIE papers as summer 2002 incorporated with updates included 2004 February. However, readers encouraged check most updated through home...
Magnetic resonance (MR) imaging with gadopentetate dimeglumine was performed in 25 patients spinal epidural abscess (SEA). Seventeen of underwent follow-up MR imaging. The studies were retrospectively reviewed. In 20 patients, diskitis the primary infectious foci; however, five developed diffuse SEA without diskitis. two most common appearances (a) homogeneous or heterogeneous enhancement solid portion and (b) thin thick around liquefied collections pus. Dural frequently seen lengthy...
We report on the correlation between flux, color and polarization variations time scales of days--months in blazars, discuss their universal aspects. performed monitoring 42 blazars optical near-infrared bands from 2008 to 2010 using TRISPEC attached "Kanata" 1.5-m telescope. found that 28 exhibited "bluer-when-brighter" trends whole or a part time-series data sets. This corresponds 88% objects were observed for >10 days. Thus, our observation unambiguously confirmed trend is common emission...
Abstract MUC1 is a shared tumor antigen expressed on >80% of human cancers. We completed the first prophylactic cancer vaccine clinical trial based non-viral antigen, MUC1, in healthy individuals at-risk for colon cancer. This provided unique source potentially effective and safe immunotherapeutic drugs, fully-human antibodies affinity-matured host to antigen. purified, cloned, characterized 13 IgGs specific several tumor-associated epitopes with wide range binding affinities. These bind...
Ganglioside GM3 (Siaα2-3Galβ1-4Glcβ1-1Cer) has been known to participate in insulin signaling by regulating the association of receptor caveolae microdomains (lipid rafts), which is essential for execution complete metabolic adipocytes. Macrophage-secreted factors including proinflammatory cytokines, tumor necrosis factor-α and interleukin-1β, adipose tissues have limit local adipogenesis induce resistance; however, interplay between adipocytes macrophages upon regulation expression not...
Abstract We present the results of near-infrared and optical observations BL Lac object S5 0716$+$714, carried out with KANATA telescope. 0716$+$714 has both a long-term, high-amplitude variability short-term within one night. The shortest (microvariability) time-scale is important for understanding geometry jets magnetic field, because it provides possible minimum size variation sources. Here, we report on detection 15-min in which time scales variations observed blazars. detected...
We report on optical-near-infrared photopolarimetric observations of a blazar 3C 454.3 over 200 d. The object experienced an optical outburst in July 2007. This was followed by short state fainter than $V=15.2$ mag lasting $\sim 25$ object, then, entered active during which we observed flares having timescale 3-10 showed two types features the color-magnitude relationship. One is "bluer-when-brighter" trend state, and other "redder-when-brighter" faint state. These suggest contribution...
We fabricated silver split-ring resonators (SRRs) using nanosphere lithography and measured the LC resonance wavelength of single isolated SRRs in optical range. The SRRs' sizes decreased when smaller polystyrene spheres were used as templates, their to 721 nm. corresponding observed properties was calculated circuit model; we confirmed that observational results agreed well. frequency a miniaturized SRR with constant shape also calculated. For fabricated, estimated short-wavelength limit 426
Ectopic fat accumulation plays important roles in various metabolic disorders and cardiovascular diseases. Recent studies reported that myocardial triglyceride (TG) content measured by proton magnetic resonance spectroscopy (1H-MRS) is associated with aging, diabetes mellitus, cardiac dysfunction. However, TG athletes has not yet been investigated. We performed 1H-MRS imaging 10 male endurance 15 healthy controls. Serum markers other clinical parameters including arterial stiffness were...
The purpose of this study was to clarify the difference between effects nitroglycerin (NTG) on functional stiffness in patients with and without coronary artery disease (CAD) using a newly developed index, cardio-ankle vascular index (CAVI).The two subject groups were normal controls (n=31) CAD (n=25). had no medical history not regular medications. On other hand, received various treatments like antihypertensive drugs, hypoglycemic agents, statins. This conducted under After single...
Abstract We report on optical and infrared photometric observations of a WZ Sge-type dwarf nova, V455 And during superoutburst in 2007. These were performed with the KANATA ($V$, $J$, $K_{\rm s}$ bands) MITSuME ($g^\prime$, $R_{\rm C}$, $I_{\rm C}$ telescopes. Our 6-band simultaneous allowed us to investigate temporal variation temperature size emitting region associated short-term modulations, such as early ordinary superhumps. A hot ($> $11000 K) accretion disk suddenly disappeared...
Abstract We report on multi-band photometric and polarimetric observations of the blazars AO 0235$+$164 PKS 1510$-$089. These two were active in 2008 2009, respectively. In these states, prominent short flares observed both objects, having amplitudes $\gt$1mag within 10d. The $V$$-$$J$ color became bluer when objects brighter flares. On other hand, 1510$-$089 exhibited a trend that it redder was brighter, except for its flare. This redder-when-brighter can be explained by strong contribution...
Abstract We developed a method of separating long-term trend from observed temporal variations polarization in blazars using Bayesian approach. The variation the vector is apparently erratic most blazars, while several objects have occasionally exhibited systematic variations, for example an increase degree associated with flare total flux. assume that superposition two distinct components: and short-term component responsible short flares. Our model estimates satisfies condition flux...