A5031987164- Autoimmune Bullous Skin Diseases
- Vascular Malformations and Hemangiomas
- Cutaneous Melanoma Detection and Management
- Tumors and Oncological Cases
- Skin and Cellular Biology Research
- Cutaneous lymphoproliferative disorders research
- Melanoma and MAPK Pathways
- Nail Diseases and Treatments
- Neonatal skin health care
- Parvovirus B19 Infection Studies
- Urticaria and Related Conditions
- Autoimmune and Inflammatory Disorders
- Genetic and rare skin diseases.
- Sarcoma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Dermatology and Skin Diseases
- DNA Repair Mechanisms
- Dermatological and Skeletal Disorders
- Chemotherapy-related skin toxicity
- Histiocytic Disorders and Treatments
- Contact Dermatitis and Allergies
- Social Media in Health Education
- Dermatological and COVID-19 studies
- Fungal Infections and Studies
University of Minnesota
2015-2024
University of Minnesota Medical Center
2019-2022
Twin Cities Orthopedics
2022
University Dermatology
2021
University of Minnesota Children's Hospital
2020
University of Minnesota System
2020
Abstract Capillary malformation‐arteriovenous malformation (CM‐AVM) syndrome is an autosomal dominant condition characterized by multifocal, noncontiguous pink patches on the skin that often have a surrounding pale halo. In some cases, association with fast flow, arteriovenous (AVM) can be identified. Here, we describe case report of 16‐year‐old woman CM‐AVM and significant cardiac compromise successfully treated trametinib, mitogen‐activated protein kinase (MEK) inhibitor.
Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic disease association with mental health needs further study.
Abstract Background Systemic sirolimus (rapamycin) has recently been found effective in treating complex vascular anomalies by reducing the size and associated complications. Many have a cutaneous component, thus, we sought to determine whether topical administration of may be an therapy, as data on use are limited. Objective We reviewed efficacy tolerability formulations treatment various simple combined malformations tumors. Methods Eighteen patients with any anomaly treated exclusively...
Abstract Background The mitogen‐activated protein kinase (MAPK) pathway is a target for the treatment of growing number malignancies. cutaneous reactions to medications that inhibit this have not been described in children. Methods A retrospective chart review was completed eight children with neural tumors treated MAPK extracellular signal‐regulated inhibitor trametinib. All were evaluated by pediatric dermatologist documentation findings. Results patients had at least two separate skin...
For infantile hemangiomas (IH) requiring treatment, including those in high-risk locations or the setting of ulceration, oral propranolol is first-line therapy. Here, we present three cases hemangioma with worsening ulceration following initiation escalation at standard doses.
Pemphigus herpetiformis (PH) is characterized by grouped vesicular or papular pruritic lesions with histologic and immunopathologic features of pemphigus. PH can manifest at any age, paraneoplastic cases have been reported. We describe a healthy boy born acral crateriform erosions the hands feet whose 35-year-old mother had similar lesions. Biopsies from both patients were most consistent PH. The was diagnosed high-grade B-cell non-Hodgkin lymphoma began chemotherapy dexamethasone, her...
Abstract Soft tissue tumors are a known, albeit uncommon, cause of cutaneous malignancy in children. Little is known about which types and how frequently these initially present the skin or subcutis Using data from 2000‐2014 SEER ‐18 database, we have identified 12 malignant soft tumor types, presented children over 50% cases.
Abstract High‐flow vascular malformations have been associated with multiple syndromes including capillary malformation–arteriovenous malformation (CM–AVM) syndrome, hereditary hemorrhagic telangiectasia and less commonly, phosphatase tensin homolog hamartoma tumor syndrome (PHTS). We present a series of three patients clinically challenging complex AVMs who were found to underlying PHTS. In all patients, diagnosis was delayed, the presence AVM prompted sampling genetic testing for PHTS in...
There are little published data on the transition of care in EB. We conducted a survey study recruiting EB patients from Dystrophic Research Association (debra) website and centers caring for high numbers United States internationally Sept 17, 2019 to Nov 3, 2021. The majority participants had not discussed with their healthcare providers, nor needs be required as an adult. Ongoing pediatric subspecialty was reported by 12% adults, most commonly dermatology. Identified barriers included...
Conradi-Hünermann-Happle syndrome is rare X-linked dominant associated with stippled epiphyseal calcifications, congenital cataracts, Blaschkoid ichthyosiform scaling, and follicular atrophoderma. This case describes a novel finding of hypocalcemia hypoparathyroidism in an infant syndrome.
Abstract Background/Objective Relative to adults, rates of melanoma are lower in children. Due its rarity, it is difficult assess the incidence, trends, and outcomes this malignancy. Much our understanding comes from single institution or regional cancer registries which may not be large enough detect subtleties burden pediatric melanoma. Methods Data 2004 2016 National Cancer Database were analyzed; database captures approximately 70% all diagnoses United States. Results Our analysis...