A5028483155- Genetic and rare skin diseases.
- Dermatology and Skin Diseases
- Vascular Malformations and Hemangiomas
- Autoimmune Bullous Skin Diseases
- Skin and Cellular Biology Research
- Food Allergy and Anaphylaxis Research
- Vascular Malformations Diagnosis and Treatment
- Cancer and Skin Lesions
- Nail Diseases and Treatments
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Acne and Rosacea Treatments and Effects
- Parvovirus B19 Infection Studies
- Hedgehog Signaling Pathway Studies
- Contact Dermatitis and Allergies
- Cutaneous lymphoproliferative disorders research
- Child Nutrition and Feeding Issues
- Eosinophilic Disorders and Syndromes
- melanin and skin pigmentation
- Neonatal skin health care
- Autoimmune and Inflammatory Disorders
- Antifungal resistance and susceptibility
- T-cell and B-cell Immunology
Yale University
2015-2024
American Academy of Dermatology
2016
Adult and Pediatric Dermatology
2015
Society For Pediatric Dermatology
2015
Yale New Haven Hospital
2007-2012
Pediatrics and Genetics
2005-2008
University of California, San Francisco
2006
Pima County Health Department
2006
University of British Columbia
2006
Schneider Children's Hospital
2006
Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors, they have unique ability to involute after proliferation, often leading primary care providers assume will resolve without intervention or consequence. Unfortunately, a subset IHs rapidly develop complications, resulting in pain, functional impairment, permanent disfigurement. As result, clinician has task determining which lesions require early consultation with specialist. Although several recent...
To characterize the atypical cutaneous presentations in coxsackievirus A6 (CVA6)-associated North American enterovirus outbreak of 2011-2012.We performed a retrospective case series pediatric patients who presented with cases hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic dermatology centers. Patients were included if they tested positive for CVA6 or met clinical criteria HFMD (an enanthem exanthem characteristic unusual morphology extent findings). We...
Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic disease association with mental health needs further study.
Generalized severe junctional epidermolysis bullosa (GS-JEB) is an incurable and fatal autosomal recessively inherited blistering skin disease caused by mutations in the LAMA3, LAMB3, or LAMC2 genes. Most of these are nonsense that create premature termination codons lead to impaired production functional laminin 332, a protein needed for epidermal-dermal adherence. Gentamicin induces readthrough restores full-length various genetic diseases. Using primary keratinocytes from three GS-JEB...
Abstract The purpose of this brief communication is to highlight emerging evidence regarding potential benefits supporting early rather than delayed peanut introduction during the period complementary food in infants. This document should be considered as interim guidance based on consensus among following organizations: American Academy Allergy, Asthma, and Immunology, Pediatrics, College Australasian Society Clinical Immunology Canadian Allergy European Israel Association Japanese for...
Abstract Epidermolysis bullosa pruriginosa (EBP) is a variant of dystrophic epidermolysis characterized by intense pruritus and prurigo nodularis‐like lesions. While medical therapies for EBP exist, current treatments are not consistently effective, symptoms often cause decreased quality life. Here, we report two cases treated with dupilumab, which improved skin findings. Both patients have been on dupilumab over one year sustained improvement no adverse effects; although in patient,...
Significance Chilblain diagnoses have increased during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and been attributed to viral infection a subsequent robust antiviral immune response. As result, providers managed these cases differently than idiopathic chilblains, which are associated with cold exposure. The relationship between chilblains SARS-CoV-2 infection, however, remains unclear as most patients do not test positive for SARS-CoV-2–specific PCR or...
Junctional epidermolysis bullosa (JEB) is an incurable blistering skin disorder with high infant mortality often caused by nonsense variants in the genes that encode laminin 332.To evaluate safety and outcomes following intravenous gentamicin readthrough therapy subsequent 332 expression patients JEB.This open-label, pilot nonrandomized clinical trial assessed 1 course of low- or high-dose gentamicin, including follow-up at 30 90 days after treatment. Five pediatric JEB (2 intermediate 3...