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Jordan Valdez

ORCID: 0000-0003-1313-190X
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A5063524413
Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 diagnosis using AI
  • SARS-CoV-2 detection and testing
  • Long-Term Effects of COVID-19
  • Parvovirus B19 Infection Studies
  • Advanced biosensing and bioanalysis techniques
  • Mycobacterium research and diagnosis
  • Lymphoma Diagnosis and Treatment
  • Digital Imaging for Blood Diseases
  • Viral gastroenteritis research and epidemiology
  • Clostridium difficile and Clostridium perfringens research
  • Dermatological and COVID-19 studies
  • Dental Research and COVID-19
  • Cell Image Analysis Techniques
  • COVID-19 and Mental Health
  • Gut microbiota and health
  • Biosensors and Analytical Detection
  • COVID-19 Impact on Reproduction
  • Streptococcal Infections and Treatments
  • Chronic Lymphocytic Leukemia Research
  • Immunodeficiency and Autoimmune Disorders

Yale University
 2020-2022

Hospital Privado
 2007

 Longitudinal analyses reveal immunological misfiring in severe COVID-19
OPENALEX - Publications 
Carolina Lucas Patrick Wong Jon Klein Tiago B. R. Castro Julio Silva and 95 more Maria E. Sundaram Mallory K. Ellingson Tianyang Mao Ji Eun Oh Benjamin Israelow Takehiro Takahashi Maria Tokuyama Peiwen Lu Arvind Venkataraman Annsea Park Subhasis Mohanty Haowei Wang Anne L. Wyllie Chantal B. F. Vogels Rebecca Earnest Sarah Lapidus Isabel M. Ott Adam J. Moore M. Catherine Muenker John Fournier Melissa Campbell Camila D. Odio Arnau Casanovas‐Massana Abeer Obaid Alice Lu-Culligan Allison Nelson Anderson F. Brito Ángela Núñez Anjelica Martin Annie Watkins Bertie Geng Chaney C. Kalinich Christina A. Harden Codruta Todeasa Cole Jensen Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Eric Song Erin Silva Eriko Kudo Giuseppe DeIuliis Harold Rahming Hong‐Jai Park Irene Matos Jessica Nouws Jordan Valdez Joseph R. Fauver Joseph K. Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Mary E. Petrone Maxine Kuang Maura Nakahata Melissa Campbell Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Nicole Sonnert Nida Naushad Pavithra Vijayakumar Rick Martinello Rupak Datta Ryan Handoko Santos Bermejo Sarah Prophet Sean Bickerton Sofia Velazquez Tara Alpert Tyler Rice William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong Roy S. Herbst Albert C. Shaw Ruslan Medzhitov Wade L. Schulz Nathan D. Grubaugh Charles S. Dela Cruz Shelli Farhadian Albert I. Ko Saad B. Omer Akiko Iwasaki

10.1038/s41586-020-2588-y article EN other-oa Nature 2020-07-27
 Sex differences in immune responses that underlie COVID-19 disease outcomes
OPENALEX - Publications 
Takehiro Takahashi Mallory K. Ellingson Patrick Wong Benjamin Israelow Carolina Lucas and 93 more Jon Klein Julio Silva Tianyang Mao Ji Eun Oh Maria Tokuyama Peiwen Lu Arvind Venkataraman Annsea Park Feimei Liu Amit Meir Jonathan Sun Eric Y. Wang Arnau Casanovas‐Massana Anne L. Wyllie Chantal B. F. Vogels Rebecca Earnest Sarah Lapidus Isabel M. Ott Adam J. Moore Kelly Anastasio Michael H. Askenase Maria Batsu Hannah E. Beatty Santos Bermejo Sean Bickerton Kristina Brower Molly L. Bucklin Staci Cahill Melissa Campbell Yiyun Cao Edward Courchaine Rupak Datta Giuseppe DeIuliis Bertie Geng Laura Glick Ryan Handoko Chaney C. Kalinich William Khoury-Hanold Daniel Kim Lynda Knaggs Maxine Kuang Eriko Kudo Joseph K. Lim Melissa Linehan Alice Lu-Culligan Amyn A. Malik Anjelica Martin Irene Matos David McDonald Maksym Minasyan Subhasis Mohanty M. Catherine Muenker Nida Naushad Allison Nelson Jessica Nouws Marcella Nuñez-Smith Abeer Obaid Isabel M. Ott Hong‐Jai Park Xiaohua Peng Mary E. Petrone Sarah Prophet Harold Rahming Tyler Rice Kadi-Ann Rose Lorenzo R. Sewanan Lokesh Sharma Denise Shepard Erin Silva Michael Simonov Mikhail Smolgovsky Eric Song Nicole Sonnert Yvette Strong Codruta Todeasa Jordan Valdez Sofia Velazquez Pavithra Vijayakumar Haowei Wang Annie Watkins Elizabeth B. White Yexin Yang Albert C. Shaw John Fournier Camila D. Odio Shelli Farhadian Charles S. Dela Cruz Nathan D. Grubaugh Wade L. Schulz Aaron M. Ring Albert I. Ko Saad B. Omer Akiko Iwasaki

There is increasing evidence that coronavirus disease 2019 (COVID-19) produces more severe symptoms and higher mortality among men than women1–5. However, whether immune responses against acute respiratory syndrome (SARS-CoV-2) differ between sexes, such differences correlate with the sex difference in course of COVID-19, currently unknown. Here we examined viral loads, SARS-CoV-2-specific antibody titres, plasma cytokines blood-cell phenotyping patients moderate COVID-19 who had not...

10.1038/s41586-020-2700-3 article EN other-oa Nature 2020-08-26
 Diverse functional autoantibodies in patients with COVID-19
OPENALEX - Publications 
Eric Y. Wang Tianyang Mao Jon Klein Yile Dai John D. Huck and 86 more Jillian R. Jaycox Feimei Liu Ting Zhou Benjamin Israelow Patrick Wong Andreas Coppi Carolina Lucas Julio Silva Ji Eun Oh Eric Song Emily S. Perotti Neil S. Zheng Suzanne Fischer Melissa Campbell John Fournier Anne L. Wyllie Chantal B. F. Vogels Isabel M. Ott Chaney C. Kalinich Mary E. Petrone Anne E. Watkins Abeer Obaid Adam J. Moore Arnau Casanovas‐Massana Alice Lu-Culligan Allison Nelson Ángela Núñez Anjelica Martin Bertie Geng Camila D. Odio Christina A. Harden Codruta Todeasa Cole Jensen Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Erin Silva Eriko Kudo Giuseppe DeIuliis Harold Rahming Hong‐Jai Park Irene Matos Jessica Nouws Jordan Valdez Joseph K. Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Maxine Kuang Maura Nakahata Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Nicole Sonnert Nida Naushad Pavithra Vijayakumar Rick Martinello Rupak Datta Ryan Handoko Santos Bermejo Sarah Prophet Sean Bickerton Sofia Velazquez Tyler Rice William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong Charles S. Dela Cruz Shelli Farhadian Wade L. Schulz Shuangge Ma Nathan D. Grubaugh Albert I. Ko Akiko Iwasaki Aaron M. Ring

10.1038/s41586-021-03631-y article EN other-oa Nature 2021-05-19
 Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs
OPENALEX - Publications 
Anne L. Wyllie John Fournier Arnau Casanovas-Massana Melissa Campbell Maria Tokuyama and 45 more Pavithra Vijayakumar Bertie Geng M. Catherine Muenker Adam J. Moore Chantal B.F. Vogels Mary E. Petrone Isabel M. Ott Peiwen Lu Arvind Venkataraman Alice Lu-Culligan Jon Klein Rebecca Earnest Michael Simonov Rupak Datta Ryan Handoko Nida Naushad Lorenzo R. Sewanan Jordan Valdez Elizabeth B. White Sarah Lapidus Chaney C. Kalinich Xiaodong Jiang Daniel J. Kim Eriko Kudo Melissa Linehan Tianyang Mao Miyu Moriyama Ji Eun Oh Annsea Park Julio Silva Eric Song Takehiro Takahashi Manabu Taura Orr-El Weizman Patrick Wong Yexin Yang Santos Bermejo Camila D. Odio Saad B. Omer Charles S. Dela Cruz Shelli Farhadian Richard A. Martinello Akiko Iwasaki Nathan D. Grubaugh Albert I. Ko

Abstract Rapid and accurate SARS-CoV-2 diagnostic testing is essential for controlling the ongoing COVID-19 pandemic. The current gold standard diagnosis real-time RT-PCR detection of from nasopharyngeal swabs. Low sensitivity, exposure risks to healthcare workers, global shortages swabs personal protective equipment, however, necessitate validation new approaches. Saliva a promising candidate diagnostics because (1) collection minimally invasive can reliably be self-administered (2) saliva...

10.1101/2020.04.16.20067835 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2020-04-22
 SalivaDirect: A simplified and flexible platform to enhance SARS-CoV-2 testing capacity
OPENALEX - Publications 
Chantal B. F. Vogels Anne E. Watkins Christina A. Harden Doug E. Brackney Jared Shafer and 81 more Jianhui Wang César Caraballo Chaney C. Kalinich Isabel M. Ott Joseph R. Fauver Eriko Kudo Peiwen Lu Arvind Venkataraman Maria Tokuyama Adam J. Moore M. Catherine Muenker Arnau Casanovas‐Massana John Fournier Santos Bermejo Melissa Campbell Rupak Datta Allison Nelson Charles S. Dela Cruz Albert I. Ko Akiko Iwasaki Harlan M. Krumholz J.D. Matheus Pei Hui Chen Liu Shelli Farhadian Robby Sikka Anne L. Wyllie Nathan D. Grubaugh Kelly Anastasio Michael H. Askenase Maria Batsu Sean Bickerton Kristina Brower Molly L. Bucklin Staci Cahill Yiyun Cao Edward Courchaine Giuseppe DeIuliis Rebecca Earnest Bertie Geng Benjamin Israelow Ryan Handoko William Khoury-Hanold Daniel Kim Lynda Knaggs Maxine Kuang Sarah Lapidus Joseph K. Lim Melissa Linehan Alice Lu-Culligan Anjelica Martin Irene Matos David McDonald Maksym Minasyan Maura Nakahata Nida Naushad Jessica Nouws Abeer Obaid Camila D. Odio Ji Eun Oh Saad B. Omer Annsea Park Hong‐Jai Park Xiaohua Peng Mary E. Petrone Sarah Prophet Tyler Rice Kadi-Ann Rose Lorenzo R. Sewanan Lokesh Sharma Albert C. Shaw Denise Shepard Mikhail Smolgovsky Nicole Sonnert Yvette Strong Codruta Todeasa Jordan Valdez Sofia Velazquez Pavithra Vijayakumar Elizabeth B. White Yexin Yang

10.1016/j.medj.2020.12.010 article EN publisher-specific-oa Med 2020-12-26
 Delayed production of neutralizing antibodies correlates with fatal COVID-19
OPENALEX - Publications 
Carolina Lucas Jon Klein Maria E. Sundaram Feimei Liu Patrick Wong and 95 more Julio Silva Tianyang Mao Ji Eun Oh Subhasis Mohanty Jiefang Huang Maria Tokuyama Peiwen Lu Arvind Venkataraman Annsea Park Benjamin Israelow Chantal B. F. Vogels M. Catherine Muenker C‐Hong Chang Arnau Casanovas‐Massana Adam J. Moore Joseph Zell John Fournier Abeer Obaid Alexander J. Robertson Alice Lu-Culligan Alice Zhao Allison Nelson Anderson F. Brito Ángela Núñez Anjelica Martin Anne E. Watkins Bertie Geng Caitlin J. Chun Chaney C. Kalinich Christina A. Harden Codruta Todeasa Cole Jensen Coriann E. Dorgay Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Eric Song Erin Silva Eriko Kudo Giuseppe DeIuliis Harold Rahming Hong‐Jai Park Irene Matos Isabel M. Ott Jessica Nouws Jordan Valdez Joseph R. Fauver Joseph K. Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Mary E. Petrone Maxine Kuang Maura Nakahata Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Natasha C. Balkcom Nicole Sonnert Nida Naushad Pavithra Vijayakumar Rick Martinello Rupak Datta Ryan Handoko Santos Bermejo Sarah Prophet Sean Bickerton Sofia Velazquez Tara Alpert Tyler Rice William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong Zitong Lin Anne L. Wyllie Melissa Campbell Alfred Ian Lee Hyung J. Chun Nathan D. Grubaugh Wade L. Schulz Shelli Farhadian Charles S. Dela Cruz Aaron M. Ring Albert C. Shaw

10.1038/s41591-021-01355-0 article EN other-oa Nature Medicine 2021-05-05
 Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
OPENALEX - Publications 
Lucie Bernard Mericien Venzon Jon Klein Jordan E. Axelrad Chenzhen Zhang and 81 more Alexis Sullivan Grant Hussey Arnau Casanovas‐Massana María G. Noval Ana M. Valero-Jimenez Juan Gago Gregory Putzel Alejandro Pironti Evan Wilder Abeer Obaid Alice Lu-Culligan Allison Nelson Anderson F. Brito Ángela Núñez Anjelica Martin Annie Watkins Bertie Geng Chaney C. Kalinich Christina A. Harden Codruta Todeasa Cole Jensen Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Eric Song Erin Silva Eriko Kudo Giuseppe DeIuliis Harold Rahming Hong‐Jai Park Irene Matos Jessica Nouws Jordan Valdez Joseph R. Fauver Joseph Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Mary E. Petrone Maxine Kuang Maura Nakahata Melissa Campbell Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Nicole Sonnert Nida Naushad Pavithra Vijayakumar Rick Martinello Rupak Datta Ryan Handoko Santos Bermejo Sarah Prophet Sean Bickerton Sofia Velazquez Tara Alpert Tyler Rice William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong Lorna E. Thorpe Dan R. Littman Meike Dittmann Kenneth A. Stapleford Bo Shopsin Victor J. Torres Albert I. Ko Akiko Iwasaki Ken Cadwell Jonas Schlüter

Abstract Although microbial populations in the gut microbiome are associated with COVID-19 severity, a causal impact on patient health has not been established. Here we provide evidence that dysbiosis is translocation of bacteria into blood during COVID-19, causing life-threatening secondary infections. We first demonstrate SARS-CoV-2 infection induces mice, which correlated alterations to Paneth cells and goblet cells, markers barrier permeability. Samples collected from 96 patients at two...

10.1038/s41467-022-33395-6 article EN cc-by Nature Communications 2022-11-01
 Multiscale PHATE identifies multimodal signatures of COVID-19
OPENALEX - Publications 
Manik Kuchroo Jessie Huang Patrick Wong Jean‐Christophe Grenier Dennis Shung and 95 more Alexander Tong Carolina Lucas Jon Klein Daniel B. Burkhardt Scott Gigante Abhinav Godavarthi Bastian Rieck Benjamin Israelow Michael Simonov Tianyang Mao Ji Eun Oh Julio Silva Takehiro Takahashi Camila D. Odio Arnau Casanovas‐Massana John Fournier Abeer Obaid Adam J. Moore Alice Lu-Culligan Allison Nelson Anderson F. Brito Ángela Núñez Anjelica Martin Anne L. Wyllie Annie Watkins Annsea Park Arvind Venkataraman Bertie Geng Chaney C. Kalinich Chantal B. F. Vogels Christina A. Harden Codruta Todeasa Cole Jensen Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Eric Song Erin Silva Eriko Kudo Giuseppe DeIuliis Haowei Wang Harold Rahming Hong‐Jai Park Irene Matos Isabel M. Ott Jessica Nouws Jordan Valdez Joseph R. Fauver Joseph Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Kumar Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Maria Tokuyama M. Cate Muenker Mary E. Petrone Maxine Kuang Maura Nakahata Melissa Campbell Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Nathan D. Grubaugh Nicole Sonnert Nida Naushad Pavithra Vijayakumar Peiwen Lu Rebecca Earnest Rick Martinello Roy S. Herbst Rupak Datta Ryan Handoko Santos Bermejo Sarah Lapidus Sarah Prophet Sean Bickerton Sofia Velazquez Subhasis Mohanty Tara Alpert Tyler Rice Wade L. Schulz William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong Shelli Farhadian

10.1038/s41587-021-01186-x article EN Nature Biotechnology 2022-02-28
 High-resolution epitope mapping and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19
OPENALEX - Publications 
Winston Haynes Kathy Kamath Joel Bozekowski Elisabeth Baum Melissa Campbell and 80 more Arnau Casanovas‐Massana Patrick S. Daugherty Charles S. Dela Cruz Abhilash Dhal Shelli Farhadian Lynn Fitzgibbons John Fournier Michael Jhatro Gregory J. Jordan Jon Klein Carolina Lucas Debra Kessler Larry L. Luchsinger Brian Martinez M. Catherine Muenker Lauren Pischel Jack Reifert Jaymie R. Sawyer Rebecca Waitz Elsio A. Wunder Minlu Zhang Kelly Anastasio Michael H. Askenase Natasha C. Balkcom Maria Batsu Santos Bermejo Kristina Brower Molly L. Bucklin Staci Cahill Yiyun Cao Michael Chiorazzi Caitlin J. Chun Rupak Datta Giuseppe DeIuliis Coriann E. Dorgay Rebecca Earnest John Fournier Bertie Geng Ryan Handoko William Khoury-Hanold Roy S. Herbst Lynda Knaggs Maxine Kuang Sarah Lapidus Zitong Lin Peiwen Lu Tianyang Mao Anjelica Martin Irene Matos David McDonald Maksym Minasyan Adam J. Moore Nida Naushad Allison Nelson Jessica Nouws Ángela Núñez Hong‐Jai Park Xiaohua Peng Alexander J. Robertson Tyler Rice Kadi-Ann Rose Wade L. Schulz Lorenzo R. Sewanan Lokesh Kumar Sharma Denise Shepard Julio Silva Michael Simonov Mikhail Smolgovsky Nicole Sonnert Ariktha Srivathsan Yvette Strong Codruta Todeasa Jordan Valdez Sofia Velazquez Pavithra Vijayakumar Elizabeth B. White Alice Zhao Akiko Iwasaki Albert I. Ko John Shon

As Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to spread, characterization of its antibody epitopes, emerging strains, related coronaviruses, and even the human proteome in naturally infected patients can guide development effective vaccines therapies. Since traditional epitope identification tools are dependent upon pre-defined peptide sequences, they not readily adaptable diverse viral proteomes. The Serum Epitope Repertoire Analysis (SERA) platform leverages a...

10.1038/s42003-021-02835-2 article EN cc-by Communications Biology 2021-11-22
 Lack of association between pandemic chilblains and SARS-CoV-2 infection
OPENALEX - Publications 
Jeff Gehlhausen Alicia J. Little Christine J. Ko Marc Emmenegger Carolina Lucas and 84 more Patrick Wong Jon Klein Peiwen Lu Tianyang Mao Jillian R. Jaycox Eric Wang Nelson Ugwu Cate Muenker Dilgash Mekael Rhonda Q. Klein Robert Patrignelli Richard J. Antaya Jennifer M. McNiff William Damsky Kathy Kamath John Shon Aaron M. Ring İnci Yıldırım Saad B. Omer Albert I. Ko Adriano Aguzzi Akiko Iwasaki Abeer Obaid Alice Lu-Culligan Allison Nelson Anderson F. Brito Ángela Núñez Anjelica Martin Annie Watkins Bertie Geng Chaney C. Kalinich Christina A. Harden Codruta Todeasa Cole Jensen Daniel Kim David McDonald Denise Shepard Edward Courchaine Elizabeth B. White Eric Song Erin Silva Eriko Kudo Giuseppe DeIuliis Harold Rahming Hong‐Jai Park Irene Matos Jessica Nouws Jordan Valdez Joseph R. Fauver Joseph K. Lim Kadi-Ann Rose Kelly Anastasio Kristina Brower Laura Glick Lokesh Sharma Lorenzo R. Sewanan Lynda Knaggs Maksym Minasyan Maria Batsu Mary E. Petrone Maxine Kuang Maura Nakahata Melissa Campbell Melissa Linehan Michael H. Askenase Michael Simonov Mikhail Smolgovsky Nicole Sonnert Nida Naushad Pavithra Vijayakumar Rick Martinello Rupak Datta Ryan Handoko Santos Bermejo Sarah Prophet Sean Bickerton Sofia Velazquez Tara Alpert Tyler Rice William Khoury-Hanold Xiaohua Peng Yexin Yang Yiyun Cao Yvette Strong

Significance Chilblain diagnoses have increased during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and been attributed to viral infection a subsequent robust antiviral immune response. As result, providers managed these cases differently than idiopathic chilblains, which are associated with cold exposure. The relationship between chilblains SARS-CoV-2 infection, however, remains unclear as most patients do not test positive for SARS-CoV-2–specific PCR or...

10.1073/pnas.2122090119 article EN cc-by Proceedings of the National Academy of Sciences 2022-02-25
 68. Active Monitoring of a Healthcare Worker Cohort During the COVID-19 Epidemic
OPENALEX - Publications 
Rupak Datta Melissa Campbell Anne L. Wyllie Arnau Casanovas-Massana Ryan Handoko and 14 more Lorenzo R. Sewanan Nida Naushad Michael Simonov Elizabeth B. White Jordan Valdez Feimei Liu Saad B. Omer Charles S. Dela Cruz Shelli Farhadian Aaron M. Ring Akiko Iwasaki Nathan D. Grubaugh Richard A. Martinello Albert I. Ko

Abstract Background Initial CDC recommendations for passive monitoring of COVID-19 related symptoms among staff may not be sufficient in preventing the introduction and transmission SARS-CoV-2 healthcare settings. We therefore implemented active infection workers (HCWs) at an academic medical center during epidemic northeast US. Methods recruited a cohort HCWs Yale New Haven Hospital who worked units did have between March 28 June 1, 2020. During follow-up, participants provided daily...

10.1093/ofid/ofaa439.378 article EN cc-by-nc-nd Open Forum Infectious Diseases 2020-10-01
 High-dose chemotherapy followed by autologous stem-cell transplantation for Hodgkin disease using CVB as conditioning regimen
OPENALEX - Publications 
R. A. Avila Jordan Valdez Gastón Caeiro Ana Lisa Basquiera Ana Gabriela Sturich and 2 more Adriana Berretta Juan Garcia

17505 Background: Autologous stem-cell transplantation has become a widely used therapy in Hodgkin's disease. We analysed outcome, overall survival (OS) and time to progression (TTP) relapsed patients with disease undergoing autologous (ASCT) single institution. Methods: Between 1996 2006, 28 (19 males 9 females; median age 31 years old, range 10–63) underwent high dose chemotherapy CVB regimen (cyclophosphamide 6 gr/m 2 , VP-16 2.400 mg/m BCNU 450 ) support. Before transplantation, 20 had...

10.1200/jco.2007.25.18_suppl.17505 article EN Journal of Clinical Oncology 2007-06-20
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