Mary Feeney

ORCID: 0000-0003-0594-7052
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About
Contact & Profiles
Research Areas
  • Food Allergy and Anaphylaxis Research
  • Eosinophilic Esophagitis
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Child Nutrition and Feeding Issues
  • Fungal Biology and Applications
  • Infant Health and Development
  • Dermatology and Skin Diseases
  • Respiratory and Cough-Related Research
  • Gut microbiota and health
  • Contact Dermatitis and Allergies
  • Food Safety and Hygiene
  • Phytochemistry and Bioactivity Studies
  • Web and Library Services
  • Connective Tissue Growth Factor Research
  • Radio, Podcasts, and Digital Media
  • Medicinal Plants and Bioactive Compounds
  • Product Development and Customization
  • Digital Storytelling and Education
  • Medicinal plant effects and applications
  • Digital Games and Media
  • IL-33, ST2, and ILC Pathways
  • Library Collection Development and Digital Resources
  • Food Security and Health in Diverse Populations
  • Dietetics, Nutrition, and Education

King's College London
2015-2024

Guy's and St Thomas' NHS Foundation Trust
2016-2024

University of Bristol
2024

St Thomas' Hospital
2019-2022

Evelina London Children's Healthcare
2022

GlaxoSmithKline (United Kingdom)
2020

World Allergy Organization
2015

National Health Service
2015

Mushroom Council
2014

Commonwealth Scientific and Industrial Research Organisation
2014

The prevalence of peanut allergy among children in Western countries has doubled the past 10 years, and is becoming apparent Africa Asia. We evaluated strategies consumption avoidance to determine which strategy most effective preventing development infants at high risk for allergy.

10.1056/nejmoa1414850 article EN New England Journal of Medicine 2015-02-24

Abstract This European Academy of Allergy and Clinical Immunology guideline provides recommendations for diagnosing IgE‐mediated food allergy was developed using the Grading Recommendations, Assessment, Development Evaluations (GRADE) approach. Food diagnosis starts with an allergy‐focused clinical history followed by tests to determine IgE sensitization, such as serum allergen‐specific (sIgE) skin prick test (SPT), basophil activation (BAT), if available. Evidence sensitization should be...

10.1111/all.15902 article EN cc-by-nc Allergy 2023-10-10

Background: The enteric bacterial flora has been implicated in the pathogenesis of enterocolitis and colon cancer C57BL/6 IL‐10 knockout mice. Probiotic Lactobacilli modify are thought to have a beneficial effect on enterocolitis. We conducted controlled feeding trial mice using probiotic Lactobacillus salivarius ssp. s alivarius UCC118. Aim: To determine consumption gastrointestinal microflora, tumour development colitis Methods: Twenty were studied (10 consumed organisms milk 10 unmodified...

10.1046/j.1365-2036.2001.01027.x article EN Alimentary Pharmacology & Therapeutics 2001-08-22

Vitamin D(2) (ergocalciferol) and sterols were analyzed in mushrooms sampled nationwide the United States to update USDA Nutrient Database for Standard Reference. was assayed using HPLC with [(3)H]-vitamin D(3) internal standard by GC-FID mass spectrometric (MS) confirmation. low (0.1-0.3 μg/100 g) Agaricus bisporus (white button, crimini, portabella) enoki, moderate shiitake oyster (0.4-0.7 g), high morel, chanterelle, maitake (5.2-28.1 UV-treated portabella (3.4-20.9 significant...

10.1021/jf104246z article EN Journal of Agricultural and Food Chemistry 2011-06-13

Abstract The prevalence of allergic diseases such as rhinitis, asthma, food allergy, and atopic dermatitis has increased dramatically during the last decades, which is associated with altered environmental exposures lifestyle practices. purpose this review was to highlight potential role for dietary fatty acids, in prevention management these disorders. In addition their nutritive value, acids have important immunoregulatory effects. Fatty acid‐associated biological mechanisms, human...

10.1111/all.13764 article EN Allergy 2019-04-30

BackgroundEarly introduction of dietary peanut in high-risk infants with severe eczema, egg allergy, or both prevented allergy at 5 years age the Learning Early About Peanut Allergy (LEAP) study. The protective effect persisted after 12 months avoiding peanuts 12-month extension LEAP study (LEAP-On). It is unclear whether this benefit allergen and allergic disease specific.ObjectiveWe sought to assess early on development disease, food sensitization, aeroallergen sensitization.MethodsAsthma,...

10.1016/j.jaci.2017.09.034 article EN cc-by-nc-nd Journal of Allergy and Clinical Immunology 2017-10-31

Mushrooms are fungi, biologically distinct from plant- and animal-derived foods (fruits, vegetables, grains, dairy, protein [meat, fish, poultry, legumes, nuts, seeds]) that comprise the US Department of Agriculture food patterns operationalized by consumer-focused MyPlate messages. Although mushrooms provide nutrients found in these groups, they also have a unique nutrient profile. Classified into grouping systems their use as vegetable, mushrooms' increasing main entrées plant-based diets...

10.1097/nt.0000000000000063 article EN cc-by Nutrition Today 2014-11-01

BackgroundA randomized trial demonstrated consumption of peanut from infancy to age 5 years prevented the development allergy. An extension that effect persisted after 1 year avoidance. This follow-up examined durability tolerance at 144 months ad libitum consumption.MethodsParticipants a were assessed for allergy following an extended period eating or avoiding peanuts as desired. The primary end point was rate months.ResultsWe enrolled 508 original 640 participants (79.4%); 497 had complete...

10.1056/evidoa2300311 article EN NEJM Evidence 2024-05-28

This European Academy of Allergy and Clinical Immunology (EAACI) guideline provides recommendations for the management IgE-mediated food allergy was developed using Grading Recommendations, Assessment, Development Evaluations (GRADE) approach. Following confirmation diagnosis, allergen avoidance dietary advice (with support a specialised dietitian, if possible) together with provision written treatment plan, education on recognition allergic symptoms prescription medication including...

10.1111/all.16345 article EN cc-by Allergy 2024-10-30

Abstract Background Peanut allergy (PA) is a common, potentially life‐threatening and typically lifelong condition with significant burden of illness. However, information lacking on how persons PA (PwPA) their caregivers perceive the psychosocial impact living PA. The Allergy to Peanuts imPacting Emotions And Life 1 (APPEAL‐1) survey, conducted across Europe, investigated experience Here, we report data evaluating PwPA caregivers. Methods study was an online survey in eight European...

10.1111/all.14363 article EN cc-by-nc-nd Allergy 2020-05-13

Abstract The purpose of this brief communication is to highlight emerging evidence regarding potential benefits supporting early rather than delayed peanut introduction during the period complementary food in infants. This document should be considered as interim guidance based on consensus among following organizations: American Academy Allergy, Asthma, and Immunology, Pediatrics, College Australasian Society Clinical Immunology Canadian Allergy European Israel Association Japanese for...

10.1111/pde.12685 article EN Pediatric Dermatology 2015-09-10

Allergy to Peanuts ImPacting Emotions And Life (APPEAL-1) was a recent European multi-country questionnaire survey that highlighted the negative impacts of peanut allergy (PA) on quality life. A follow-on qualitative study, APPEAL-2, further assessed burden PA and associated coping strategies through semi-structured interviews.To gain insight used cope with manage impact these life children, teenagers caregivers.This cross-sectional study conducted in eight countries: United Kingdom, France,...

10.1111/cea.13719 article EN Clinical & Experimental Allergy 2020-08-06

Abstract Background Scleroderma (SSc) is a rare autoimmune disease characterized by vascular impairment and progressive fibrosis of the skin other organs. Oncostatin M, member IL-6 family, elevated in SSc serum was recognized as significant player various stages fibrosis. The goal this study to assess contribution OSM/OSMRβ pathway endothelial cell (EC) injury activation SSc. Methods IHC IF were used distribution OSM OSMRβ ( n = 14) healthy control 7) biopsies. Cell culture experiments...

10.1186/s13075-020-02266-0 article EN cc-by Arthritis Research & Therapy 2020-07-31

Microbial metabolism of specific dietary components, such as fiber, contribute to the sophisticated inter-kingdom dialogue in gut that maintains a stable environment with important beneficial physiological, metabolic, and immunological effects on host. Historical changes fiber intake may be contributing increase allergic hypersensitivity disorders fiber-derived metabolites are evolutionarily hardwired into molecular circuitry governing immune cell decision making processes. In this review,...

10.22541/au.163807080.07633496/v1 preprint EN Authorea (Authorea) 2021-11-28

In June 2015, the American Academy of Pediatrics endorses and accepts as its policy, "Consensus Communication on Early Peanut Introduction Prevention Allergy in High-Risk Infants." More formal guidelines regarding early-life, complementary feeding practices, risk allergy development will follow next year from National Institute Infectious Diseases (NIAID)-sponsored Working Group European Clinical Immunology (EAACI), thus, this document should be considered interim guidance. The publication...

10.1542/peds.2015-2394 article EN PEDIATRICS 2015-09-01

Abstract Introduction Food hypersensitivity (FHS), including food allergy, coeliac disease and intolerance, is a major public health issue. The Standards Agency (FSA), an independent UK Government department working to protect consumers’ wider interests in food, sought identify research priorities the area of FHS. Methods A priority setting exercise was undertaken, using methodology adapted from James Lind Alliance—the first such with respect hypersensitivity. UK‐wide consultation held...

10.1111/cea.13983 article EN Clinical & Experimental Allergy 2021-07-07

Peanut allergy (PA) is associated with marked quality-of-life (QoL) impairment. However, data are lacking on the experience and impact of living PA from perspectives persons (PwPA) their caregivers. Allergy to Peanuts imPacting Emotions And Life study 1 (APPEAL-1) was a pan-European survey investigating these perspectives. This first two articles reports clinical characteristics PwPA management practices.APPEAL-1 quantitative, online conducted in eight European countries, developed by...

10.1111/all.14414 article EN cc-by-nc Allergy 2020-05-21
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