A5007149092- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Insects and Parasite Interactions
- Transplantation: Methods and Outcomes
- Indoor Air Quality and Microbial Exposure
- Respiratory and Cough-Related Research
- Polyomavirus and related diseases
- Air Quality and Health Impacts
- Eosinophilic Esophagitis
- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Behavioral Health and Interventions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pediatric health and respiratory diseases
- Animal and Plant Science Education
- Organ Transplantation Techniques and Outcomes
- Noise Effects and Management
- Inhalation and Respiratory Drug Delivery
- Climate Change and Health Impacts
- Dermatology and Skin Diseases
- Respiratory viral infections research
- Transgenic Plants and Applications
- Mast cells and histamine
- Disaster Management and Resilience
Rho (United States)
2014-2023
Rainbow Health Ontario
2020
National Institute of Environmental Health Sciences
2005-2015
National Institutes of Health
2004-2015
Triangle
2003-2013
University of North Carolina at Chapel Hill
2009-2013
Research Triangle Park Foundation
2008-2010
The prevalence of peanut allergy among children in Western countries has doubled the past 10 years, and is becoming apparent Africa Asia. We evaluated strategies consumption avoidance to determine which strategy most effective preventing development infants at high risk for allergy.
In a randomized trial, the early introduction of peanuts in infants at high risk for allergy was shown to prevent peanut allergy. this follow-up study, we investigated whether rate remained low after 12 months avoidance among participants who had consumed during primary trial (peanut-consumption group), as compared with those avoided (peanut-avoidance group).At end instructed all avoid months. The outcome percentage 12-month period, when were 72 age.We enrolled 556 628 eligible (88.5%) from...
BackgroundEarly introduction of dietary peanut in high-risk infants with severe eczema, egg allergy, or both prevented allergy at 5 years age the Learning Early About Peanut Allergy (LEAP) study. The protective effect persisted after 12 months avoiding peanuts 12-month extension LEAP study (LEAP-On). It is unclear whether this benefit allergen and allergic disease specific.ObjectiveWe sought to assess early on development disease, food sensitization, aeroallergen sensitization.MethodsAsthma,...
IntroductionThere is no detailed comparison of allergen-specific immunoglobulin responses following sublingual immunotherapy (SLIT) and subcutaneous (SCIT).ObjectiveWe sought to compare nasal systemic timothy grass pollen (TGP)-specific antibody during 2 years SCIT SLIT 1 year after treatment discontinuation in a double-blind, double-dummy, placebo-controlled trial.MethodsNasal fluid serum were obtained yearly (per-protocol population, n = 84). TGP-specific IgA1, IgA2, IgG4, IgG, IgE...
BackgroundPeanut allergy affects 1% to 2% of European children. Early introduction peanut into the diet reduces in high-risk infants.ObjectiveWe aimed determine optimal target populations and timing products prevent general population.MethodsData from Enquiring About Tolerance (EAT; n = 1303; normal risk; 3-year follow-up; ISRCTN14254740) Learning Peanut Allergy study (LEAP; 640; high 5-year NCT00329784) randomized controlled trials plus Sensitization (PAS; 194; low very follow-up)...
Rationale: Acute rejection, manifesting as lymphocytic inflammation in a perivascular (acute rejection [AR]) or peribronchiolar (lymphocytic bronchiolitis [LB]) distribution, is common lung transplant recipients and increases the risk for chronic graft dysfunction.Objectives: To evaluate clinical factors associated with biopsy-proven acute during first post-transplant year present-day, five-center cohort.Methods: We analyzed prospective diagnoses of AR LB from over 2,000 biopsies 400 newly...