Denise C. Babineau

ORCID: 0000-0002-9776-9080
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • Allergic Rhinitis and Sensitization
  • Food Allergy and Anaphylaxis Research
  • Dermatology and Skin Diseases
  • Renal cell carcinoma treatment
  • Obstructive Sleep Apnea Research
  • Renal and related cancers
  • Pediatric Urology and Nephrology Studies
  • Respiratory and Cough-Related Research
  • Contact Dermatitis and Allergies
  • Pelvic floor disorders treatments
  • IL-33, ST2, and ILC Pathways
  • Sleep and related disorders
  • Ureteral procedures and complications
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Corneal surgery and disorders
  • Sleep and Wakefulness Research
  • Heart Rate Variability and Autonomic Control
  • Immune Cell Function and Interaction
  • Cardiovascular Health and Disease Prevention
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Opioid Use Disorder Treatment
  • Eosinophilic Esophagitis
  • Neuroscience of respiration and sleep

RTI International
2024-2025

Rho (United States)
2014-2023

Communities In Schools of Orange County
2018

Case Western Reserve University
2007-2015

Center for Clinical Research (United States)
2012

University School
2011

University Hospitals Cleveland Medical Center
2011

Case Comprehensive Cancer Center
2010

Cleveland Clinic
2006-2008

Cleveland Clinic Lerner College of Medicine
2007

No AccessJournal of UrologyAdult urology1 Jul 2007Comparison 1,800 Laparoscopic and Open Partial Nephrectomies for Single Renal Tumors Inderbir S. Gill, Louis R. Kavoussi, Brian Lane, Michael L. Blute, Denise Babineau, J. Roberto Colombo, Igor Frank, Sompol Permpongkosol, Christopher Weight, Jihad H. Kaouk, W. Kattan, Andrew C. Novick GillInderbir Gill Glickman Urological Institute, Cleveland Clinic, Cleveland, Ohio , KavoussiLouis Kavoussi Departments Urology, The Johns Hopkins Hospital,...

10.1016/j.juro.2007.03.038 article EN The Journal of Urology 2007-05-12

No AccessJournal of UrologyAdult Urology1 Dec 2008Factors Predicting Renal Functional Outcome After Partial Nephrectomy Brian R. Lane, Denise C. Babineau, Emilio D. Poggio, Christopher J. Weight, Benjamin T. Larson, Inderbir S. Gill, and Andrew Novick LaneBrian Lane Department Urology, Glickman Urological Kidney Institute, Cleveland Clinic, Cleveland, Ohio , BabineauDenise Babineau Quantitative Health Sciences, PoggioEmilio Poggio WeightChristopher Weight LarsonBenjamin Larson GillInderbir...

10.1016/j.juro.2008.08.036 article EN The Journal of Urology 2008-12-01

Obstructive sleep apnea is associated with hypertension, inflammation, and increased cardiovascular risk. Continuous positive airway pressure (CPAP) reduces blood pressure, but adherence often suboptimal, the benefit beyond management of conventional risk factors uncertain. Since intermittent hypoxemia may underlie sequelae apnea, we evaluated effects nocturnal supplemental oxygen CPAP on markers risk.We conducted a randomized, controlled trial in which patients disease or multiple were...

10.1056/nejmoa1306766 article EN New England Journal of Medicine 2014-06-11

Small renal masses are increasing in incidence. Most tumors 7 cm or less treated with radical partial nephrectomy but clinicians increasingly relying on ablative therapies and observation for some small masses. We present novel nomograms that predict the likelihood of benign, likely indolent potentially aggressive pathological findings based only readily identifiable preoperative factors.Information all nephrectomies performed at a single institution was collected an institutional review...

10.1016/j.juro.2007.03.106 article EN The Journal of Urology 2007-06-12

A proportion of patients under surveillance for recurrent bladder carcinoma with no immediate evidence tumor recurrence have positive multitarget fluorescence in situ hybridization (FISH; UroVysion, Vysis, Downers Grove, IL) results. The course these "anticipatory positive" cases and the time to remains unknown. We followed up 250 urine cytologic results, concurrent FISH, cystoscopic examination urothelial carcinoma. Of 81 (32.4%) FISH-positive developed 60 (74.0%). 169 (67.6%) FISH-negative...

10.1309/adjl7e810u1h42bj article EN American Journal of Clinical Pathology 2007-02-01

To address whether treatment of sleep apnea improves glucose tolerance.Randomized, double-blind crossover study.Sleep clinic referrals.50 subjects with moderate to severe (AHI > 15) and impaired tolerance.Subjects were randomized 8 weeks CPAP or sham CPAP, followed by the alternate therapy after a one-month washout. After each treatment, underwent 2-hour OGTT, polysomnography, actigraphy, measurements indices control.The primary outcome was normalization mean 2-h OGTT; secondary improvement...

10.5665/sleep.1816 article EN SLEEP 2012-04-30

We compared the postoperative and renal functional outcomes of patients undergoing open or laparoscopic partial nephrectomy for tumor in a solitary functioning kidney.Between 1999 2006, 169 30 nephrectomies were performed 7 cm smaller tumors kidney. Data collected an institutional review board approved registry median followup was 2.0 years. Preoperative glomerular filtration rates estimated with abbreviated Modification Diet Renal Disease equation.By 3 months after nephrectomy, rate...

10.1016/j.juro.2007.10.050 article EN The Journal of Urology 2008-01-28

Background. We report the 5-year outcomes from a randomized prospective trial in primary adult renal allograft recipients, designed to evaluate calcineurin inhibitor (CNI)-free immunosuppression on kidney transplant function. Methods. Sixty-one patients were either sirolimus (n=31) or cyclosporine (n=30) after basiliximab induction and mycophenolate mofetil (MMF) with steroids. Sirolimus was concentration controlled at 10–12 ng/mL for least 6 months. Results. After 5 years,...

10.1097/01.tp.0000258586.52777.4c article EN Transplantation 2007-04-15

Immunoglobulin G antibodies (Abs) to Plasmodium falciparum antigens have been associated with naturally acquired immunity symptomatic malaria.We probed protein microarrays covering 824 unique P. features plasma from residents of a community in Kenya monitored for 12 weeks (re)infection and malaria after administration antimalarial drugs. proteins recognized by Abs 88 children (aged 1-14 years) 86 adults ≥ 18 years), measured at the beginning observation period, were ranked Ab signal...

10.1093/infdis/jiv224 article EN The Journal of Infectious Diseases 2015-04-15

You have accessJournal of UrologyModerated Poster 14, Sunday, May 20, 2007, 3:30 - 5:30 pm1 Apr 2007495: Comparison 1800 Laparoscopic and Open Partial Nephrectomies for Single Renal Tumors Inderbir S. Gill, Louis R. Kavoussi, Brian Lane, Michael L. Blute, Denise Babineau, Jose Colombo, Igor Frank, Sompol Permpongkosol, Christopher J. Weight, W. Kattan, Andrew C. Novick GillInderbir Gill More articles by this author , KavoussiLouis Kavoussi LaneBrian Lane BluteMichael Blute BabineauDenise...

10.1016/s0022-5347(18)30735-3 article EN The Journal of Urology 2007-04-01

Short sleep duration is associated with systemic inflammation and diabetes; however the mechanisms by which reduced leads to these complications are unclear. One possibility may impact secretion of adipocyte derived hormones that regulate insulin resistance. In this study we assessed association between 3 adipokine levels. A total 561 adults from Cleveland Family Study underwent standardized laboratory polysomnography followed a morning fasting blood draw assayed for leptin, visfatin,...

10.1093/sleep/34.2.147 article EN SLEEP 2011-02-01

Objective: To define the relationship between Fuchs endothelial corneal dystrophy (FECD) severity and central thickness (CCT). Methods:We examined 1610 eyes from a subset of index cases, family members, unrelated control subjects with normal corneas FECD Genetics Multi-Center Study.To estimate association grade (7-point scale based on guttae confluence) CCT measured by ultrasonographic pachymetry, multivariable model was used that adjusted for eye, age, race, sex, history glaucoma or ocular...

10.1001/archopthalmol.2011.1626 article EN Archives of Ophthalmology 2012-04-01

Objectives To determine whether elderly adults with a low glomerular filtration rate ( GFR ) are at risk for anemia, hyperkalemia, acidosis, and hyperphosphatemia. Design Retrospective study. Setting Veterans Affairs Medical Center. Participants Thirteen thousand eight hundred seventy‐four veterans aged 65 older chronic kidney disease CKD between 15 60 mL/min per 1.73 m 2 . Their average age was 79. Measurements Anemia defined as hemoglobin level of less than 10 g/dL, hyperkalemia potassium...

10.1111/j.1532-5415.2011.03818.x article EN Journal of the American Geriatrics Society 2012-01-27

<b><i>Background/Aims:</i></b> Low heart rate variability (HRV) is a risk factor for adverse outcomes in the general population. We aimed to determine factors associated with HRV and evaluate association between low clinical patients chronic kidney disease (CKD). <b><i>Methods:</i></b> A 10-second electrocardiogram was obtained at baseline Chronic Renal Insufficiency Cohort (CRIC) Study. measured by standard deviation of all R-R intervals...

10.1159/000357200 article EN American Journal of Nephrology 2013-01-01

We hypothesized increasing obstructive sleep apnea (OSA) severity would be associated with nondipping blood pressure (BP) in increased cardiovascular disease (CVD) risk.

10.1097/hjh.0000000000000011 article EN Journal of Hypertension 2013-12-17
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