- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Child Abuse and Trauma
- Congenital heart defects research
- Attention Deficit Hyperactivity Disorder
- Early Childhood Education and Development
- Autism Spectrum Disorder Research
- Congenital Heart Disease Studies
- Resilience and Mental Health
- Schizophrenia research and treatment
- Child and Animal Learning Development
- COVID-19 and Mental Health
- Neuroendocrine regulation and behavior
- Health Systems, Economic Evaluations, Quality of Life
- Neural dynamics and brain function
- Attachment and Relationship Dynamics
- Maternal and Perinatal Health Interventions
- Memory and Neural Mechanisms
- Mental Health Research Topics
- COVID-19 Impact on Reproduction
- Heart Rate Variability and Autonomic Control
- Genetics and Neurodevelopmental Disorders
Children's Hospital of Philadelphia
2017-2025
University of Pennsylvania
2019-2025
Lifespan
2017-2025
University of Pennsylvania Health System
2020-2025
University of Freiburg
2024
Erasmus University Rotterdam
2024
University of California, San Diego
2023
Maastricht University
2023
University of California, Los Angeles
2023
California University of Pennsylvania
2023
Abstract COVID-19 pandemic is a global calamity posing an unprecedented opportunity to study resilience. We developed brief resilience survey probing self-reliance, emotion-regulation, interpersonal-relationship patterns and neighborhood-environment, applied it online during the acute outbreak (April 6–15, 2020), on crowdsourcing research website ( www.covid19resilience.org ) advertised through social media. evaluated level of stress (worries) regarding COVID-19: (1) contracting, (2) dying...
Comorbidity is ubiquitous in psychiatry, but it unclear how to differentiate neural mechanisms of co-occurring symptoms. Pediatric irritability and anxiety symptoms are prevalent frequently co-occur. Threat orienting pertinent both phenotypes an ideal context which examine their unique common mechanisms.To decompose the shared variances pediatric determine correlates these differentiated during threat orienting.This investigation was a cross-sectional functional magnetic resonance imaging...
Objective: In the treatment of anxiety disorders, attention bias modification therapy (ABMT) and cognitive-behavioral (CBT) may have complementary effects by targeting different aspects perturbed threat responses behaviors. ABMT target rapid, implicit reactions, whereas CBT slowly deployed responses. The authors used amygdala-based connectivity during a threat-attention task randomized controlled trial design to evaluate potential features these treatments in pediatric disorders. Method:...
Background Considerable research links threat-related attention biases to anxiety symptoms in adults, whereas extant findings on threat youth are limited and mixed. Inconsistent may arise due substantial methodological variability sample sizes, emphasizing the need for systematic large samples. The aim of this report is examine association between bias pediatric using standardized measures a large, international, multi-site sample. Methods A total 1,291 children adolescents from seven sites...
This study examined relations between behavioral inhibition (BI) assessed in toddlerhood ( n = 268) and attention biases (AB) to threat positive faces maternal‐reported anxiety when children were 5‐ 7‐year‐old. Results revealed that BI predicted at age 7 with AB toward threat, away from positive, or no bias, 7; did not predict for displaying positive. Five‐year moderate the link 7‐year anxiety. No direct association was detected; moreover, show stable across development. These findings...
Objective: Anxiety disorders are prevalent among youths and often highly impairing. Cognitive-behavioral therapy (CBT) is an effective first-line treatment. The authors investigated the brain mechanisms associated with symptom change following CBT. Methods: Unmedicated diagnosed anxiety disorder underwent 12 weeks of CBT as part two randomized clinical trials testing efficacy adjunctive computerized cognitive training. Across both trials, participants completed a threat-processing task...
Data from 3,087 persons age 45 or older in the National Health and Nutrition Survey, 1971-74, showed that subjects with lens opacifying disease had an increased odds for age-related macular degeneration (AMD) compared to those who no opacities. The crude ratio aphakic patients was 4.6 (95% CI = 2.5, 8.6). association remained after controlling age, sex, systolic blood pressure (a common risk factor) a logistic regression model. These data are consistent hypothesis light-induced damage may...
Acute stress during pregnancy can have adverse effects on maternal health and increase the risk for postpartum depression impaired mother-infant bonding. The COVID-19 pandemic represents an acute environmental stressor which it is possible to explore resilience factors that contribute outcomes. To investigate prenatal as predictors of bonding, this study recruited a diverse cohort 833 pregnant women from urban medical center in Philadelphia, Pennsylvania, assessed them once early phase...
Abstract Social communication difficulties are a transdiagnostic risk factor for psychopathology. However, few studies have examined prospective social in young children within an ecological systems framework. Our sample was 251 parent–child dyads assessed during pregnancy, postpartum, and toddlerhood (child ages 1 2). We leveraged observer ratings of child behavior, parent-reported questionnaires, geocoded data. factors at 2, including the level (gestational age), family (household income,...
Abstract The present study utilized a multilevel approach to examine developmental trajectories in risk-taking propensity. We examined the moderating role of specific executive function components, attention shifting and inhibitory control, on link between exuberant temperament infancy propensity for risk taking childhood. Risk was assessed using task previously associated with sensation seeking antisocial behaviors. Two hundred ninety-one infants were brought into lab behaviors reflecting...