A5032357407- Bone Tissue Engineering Materials
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Conducting polymers and applications
- Planarian Biology and Electrostimulation
- Polymer Surface Interaction Studies
- Advanced biosensing and bioanalysis techniques
- Graphene and Nanomaterials Applications
- Polydiacetylene-based materials and applications
- Electrochemical sensors and biosensors
- Antimicrobial Peptides and Activities
- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- Biosensors and Analytical Detection
- Electrospun Nanofibers in Biomedical Applications
- Advanced Nanomaterials in Catalysis
- Advanced Materials and Mechanics
- Electromagnetic wave absorption materials
- Supramolecular Self-Assembly in Materials
- Tactile and Sensory Interactions
- Urological Disorders and Treatments
- Dielectric materials and actuators
- Infectious Aortic and Vascular Conditions
- Wound Healing and Treatments
- MXene and MAX Phase Materials
South China University of Technology
2016-2025
South China Agricultural University
2024
Key Laboratory of Guangdong Province
2018-2022
Ministry of Education of the People's Republic of China
2020
Tiangong University
2017
Mimicking soft tissue mechanical properties and the high conductivity required for electrical transmission in native spinal cord is critical nerve regeneration scaffold designs. However, fabricating scaffolds of conductivity, tissue-like properties, excellent biocompatibility simultaneously remains a great challenge. Here, soft, highly conductive, biocompatible conducting polymer hydrogel (CPH) based on plant-derived polyphenol, tannic acid (TA), cross-linking doping polypyrrole (PPy) chains...
Hydrogels, because of their water-rich nature and soft mechanical characteristics that resemble those skin tissues, are promising materials for artificial skin. Existing piezoresistive hydrogels combine unique tissue-like sensory properties, but these often plagued by problems such as poor properties the requirement an external power supply or batteries. Here, a tough self-powered hydrogel based on polyacrylonitrile incorporating ferroelectric poly(vinylidene fluoride) (PAN-PVDF) is...
Preventing local tumor recurrence while promoting bone tissue regeneration is an urgent need for osteosarcoma treatment. However, the therapeutic efficacy of traditional photosensitizers limited, and they lack ability to regenerate bone. Here, a piezo-photo nanoheterostructure developed based on ultrasmall bismuth/strontium titanate nanocubes (denoted as Bi/SrTiO3), which achieve piezoelectric field-driven fast charge separation coupling with surface plasmon resonance efficiently generate...
The vulnerability of hydrogel electronic materials to mechanical damage due their soft nature has necessitated the development self-repairing electronics. However, such material with underwater capability as well excellent properties for application in aquatic environments is highly challenging and not yet been fully realized. This study designs a tough efficient supramolecular by synergistically combining weak hydrogen bonds (H-bonds) strong dipole-dipole interactions. resultant high...
Pathological angiogenesis frequently occurs in tumor tissue, limiting the efficiency of chemotherapeutic drug delivery and accelerating progression. However, traditional vascular normalization strategies are not fully effective limited by development resistance. Herein, inspired intervention endogenous bioelectricity vessel formation, we propose a wireless electrical stimulation therapeutic strategy, capable breaking bioelectric homeostasis within cells, to achieve normalization. Polarized...
Abstract Bone implant biomaterials are among the most used materials for clinical application. Despite significant advances in biocompatibility and osteoconductivity, conventional lack ability to cope with pathological microenvironment (inflammation, infection, residual tumors, etc.) during bone repair. Semiconductor have unique electrical, optical, ultrasound, thermal response properties, which facilitate non‐invasively controllably dynamic repair of defects. In this review, design...
The DA–PPy–GP ECHs with continuous conductive networks show high force and strain sensitivity.
Ultrafast oil/water separation based on tunable superwettability switch remains a big challenge. Here, inspired by the ultrafast water transport mechanism in sarracenia, we develop micro/nanostructured porous membrane with conducting polymer nanotip arrays through surface-initiated polymerizations. By modulating height (ranging from 49–529 nm) and redox states of nanotips, smart reversible is facile to obtain contact angles water/oil arranging 161° about 0°. Besides, liquid speed was...
Abstract Mimicking the natural bone extracellular matrix containing intrinsic topography and electrical signals is an effective way to modulate regeneration. However, simultaneously coupling of mechanobiology cues implant regeneration remains ignored. Here, authors report in situ designation titanium dioxide (TiO 2 ) nanocone/bismuth oxide (Bi O 3 nanodot heterojunctions on surface electro‐biomechanically trigger osseointegration at bone/implant interface. TiO nanocone/Bi exhibit built‐in...
Preventing local tumor recurrence and simultaneously improving bone-tissue regeneration are in great demand for osteosarcoma therapy. However, the current therapeutic implants fail to selectively suppress growth enhance osteogenesis, antitumor therapy may compromise osseointegration of bone implant. Here, based on different responses cells osteoblasts electric stimulations, we constructed ferroelectric BaTiO3 nanorod arrays (NBTO) surface titanium with switchable dynamic static electrical...
Abstract The treatment of diseases through precision phototherapy has attracted growing interest during the last decade. Remarkably, biocompatible bismuth‐based nanomaterials can be effectively activated by near‐infrared (NIR) light to fight bacterial infections and tumors. In addition, bismuth‐containing nanostructures are easy synthesized exhibit excellent NIR absorption, ideal photothermal conversion, X‐ray sensitivity for diagnosis treatment. This review outlined recent development in...
Abstract Chronic diabetic wounds pose significant challenges due to uncontrolled bacterial infections, prolonged inflammation, and impaired angiogenesis. The rapid advancement of photo‐responsive antibacterial therapy shows promise in addressing these complex issues, particularly utilizing 2D heterojunction materials, which offer unique properties. Herein, an situ sprayed Bi/BiOCl 0D/2D composite fibrin gel with the characteristics formation effective near‐infrared activation is designed for...
Abstract Traced dopamine (DA) detection is critical for the early diagnosis and prevention of some diseases such as Parkinson’s, Alzheimer schizophrenia. In this research, a novel self-supporting three dimensional (3D) bicontinuous nanoporous electrochemical biosensor was developed by Differential Pulse Voltammetry (DPV). This fabricated electrodepositing palladium nanoparticles (Pd) onto gold (NPG) wire. Because synergistic effects excellent catalytic activity Pd structure NPG wire,...
Pressure injuries/pressure ulcers (PIs/PUs) are a critical global healthcare issue and represent considerable burden on resources. Prevention of PIs/PUs is the least costly approach minimizes patient suffering compared with treatment. Besides, sustained tissue load alleviation microenvironment management most crucial properties for dressings in PI/PU prevention. Hydrogel have attracted lot attention to prevent because their unique mechanical ability manage skin. However, auxiliary...
Bacterial infection greatly affects the rate of wound healing. Both photothermal and photodynamic antibacterial therapies activated by near-infrared (NIR) light with semiconductor nanomedicine are two effective approaches to address bacterial infections, but they cannot coexist synergistically kill bacteria more efficiently because limitation band structure. Here, inspired natural core-shell structure photosynthesis simultaneously, polypyrrole (PPy) is synthesized in two-dimensional...
As minimally or non-invasive therapeutic modalities for cancer treatment, phototherapy and sonotherapy have become a new trend biomedicine because these treatments can only target the cells while leaving normal tissue undamaged intact. However, single obtain effective clinical effects when dose of nanomaterials responding to light ultrasound is high enough. Therefore, it significant develop explore multifunctional that simultaneously respond enhance synergistic sono-phototherapy in...
Heterojunctions are widely used in energy conversion, environmental remediation, and photodetection, but have not been fully explored regenerative medicine. In particular, piezoelectric heterojunctions never examined tissue regeneration. Here the development of is shown to promote bone regeneration while eradicating pathogenic bacteria through light-cellular force-electric coupling. Specifically, an array (TiO
Cancer residues around the surgical site remain a significant cause of treatment failure with cancer recurrence. To prevent recurrence and simultaneously repair surgery-caused defects, it is urgent to develop implantable biomaterials anticancer ability good biological activity. In this work, functionalized implant successfully fabricated by doping effective element selenium (Se) into potassium–sodium niobate piezoceramic, which realizes wireless combination electrotherapy chemotherapy....