A5005420630- Carcinogens and Genotoxicity Assessment
- Pesticide and Herbicide Environmental Studies
- Pesticide Exposure and Toxicity
- Occupational and environmental lung diseases
- Bone health and treatments
- Weed Control and Herbicide Applications
- Air Quality and Health Impacts
- Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Dialysis and Renal Disease Management
- Erythropoietin and Anemia Treatment
- Venous Thromboembolism Diagnosis and Management
- Statistical Methods in Clinical Trials
- Bone and Joint Diseases
- Glutathione Transferases and Polymorphisms
- Chemical Safety and Risk Management
- Occupational Health and Safety Research
- Sleep and related disorders
- Neutropenia and Cancer Infections
- Environmental Justice and Health Disparities
- Pharmacovigilance and Adverse Drug Reactions
- Iron Metabolism and Disorders
- Occupational exposure and asthma
- Radiopharmaceutical Chemistry and Applications
Aarhus University Hospital
2016-2025
Prescott College
2023
Aarhus University
2016-2022
Emory University
2006-2022
Amgen (United States)
2008-2017
Research International (United States)
2012
Monsanto (United States)
1996-2006
Dow Chemical (United States)
2001-2006
University of Missouri–St. Louis
2001
Saint Louis University
1996
Venous thromboembolism (VTE) frequently complicates cancer. Data on tumour-specific VTE predictors are limited, but may inform strategies to prevent thrombosis. We computed incidence rates (IRs) with 95% confidence intervals (CIs) for hospitalisation in a cohort of cancer patients (n=57 591) and comparison general-population (n=287 476) Denmark. The subjects entered the study 1997–2005, follow-up continued through 2006. Using Cox proportional-hazards regression, we estimated relative risks...
Background: The prevalence of metastatic bone disease in the US population is not well understood. We sought to estimate current number adults with using two large administrative data sets. Methods: Prevalence was estimated from a commercially insured cohort (ages 18–64 years, MarketScan database) and fee-for-service Medicare ≥65 5% coverage on December 31, 2008, representing approximately two-thirds each age group. searched for claims-based evidence January 1, 2004, combination relevant...
Glyphosate is the active ingredient in Roundup agricultural herbicides and other herbicide formulations that are widely used for agricultural, forestry, residential weed control. As part of Farm Family Exposure Study, we evaluated urinary glyphosate concentrations 48 farmers, their spouses, 79 children (4-18 years age). We 24-hr composite urine samples each family member day before, of, 3 days after a application. Sixty percent farmers had detectable levels on The geometric mean (GM)...
Tenosynovial giant cell tumor (TGCT) is a rare benign proliferative and inflammatory disease arising from synovia of joints, bursae, or tendon sheaths. We aimed to estimate incidence rate prevalence TGCT in Denmark, describe patient characteristics treatment modalities among patients with TGCT, risk recurrence.Using registry data on pathology examinations inpatient outpatient hospital diagnoses, we identified adult diagnoses diffuse (D-TGCT) localized (L-TGCT) between 1997 2012, followed...
Study Objectives: The primary objective was to describe trends in the 2-year limited duration prevalence of narcolepsy from 2013-2016 a large insured population with claims activity.Secondary objectives were assess other sleep disorders and frequency diagnostic testing.Methods: Nationwide medical/prescription (Symphony Health) analyzed estimate annual per 100,000 persons (obstructive apnea, idiopathic hypersomnia, rapid eye movement behavior disorder, periodic limb disorder)...
Mortality among 5,413 white males who were employed for at least two years a plutonium weapons facility was investigated to measure risks from exposures low levels of and external radiation. When compared with US death rates, fewer deaths than expected found all causes death, cancers, lung cancer. No bone cancer observed. An excess brain tumors the cohort in general. Elevated rate ratios lymphopoietic neoplasms when employees body burdens greater or equal 2 nCi those less nCi, while...
We conducted a systematic review of the epidemiologic literature for glyphosate focusing on non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM) - two cancers that were focus recent by an International Agency Research Cancer Working Group. Our approach was consistent with Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines reviews. evaluated each relevant study according to priori criteria quality: adequacy size, likelihood confounding, potential other biases...
To determine whether mortality for patients with diffuse large B-cell lymphoma who survived 5 years (DLBCL5ys) returns thereafter to general population levels. This population-based cohort study included Danish residents between January 1, 2000, and December 31, 2023. Information on diagnoses, comorbidities, vital status came from health administrative registries. Analyses 4164 DLBCL5yr patients-55% of incident patients-and 41,640 individuals the matched 10:1 by exact birth year, sex,...
ABSTRACT Purpose Fractures are a recognized consequence of androgen deprivation therapy (ADT); however, less is known about the incidence fracture in relation to timing ADT use or impact on mortality men with prostate cancer. Methods Using data from Surveillance, Epidemiology, and End Results–Medicare linked database, we estimated adjusted hazard ratios (aHRs) using time‐dependent Cox regression for related recency exposure dose among cancer patients gonadotropin‐releasing hormone (GnRH)...
We estimated 2,4-dichlorophenoxyacetic acid (2,4-D) exposure and systemic dose in farm family members following an application of 2,4-D on their farm.
Observational studies relating epoetin alfa (EPO) dose and mortality frequently use analytic methods that do not control time-dependent confounding by indication (CBI). The relationship between EPO 1-year mortality, adjusting for the effects of CBI, was examined using a marginal structural model.This retrospective cohort study included 27,791 hemodialysis patients July 2000 June 2002. Patients were grouped at successive 2-wk intervals into zero-dose category or four nonzero-dose categories....
Serum phosphate is a key parameter in the management of chronic kidney disease-mineral and bone disorder (CKD-MBD). The timing measurement not standardized current guidelines. Since optimal range these biomarkers may vary depending on duration interdialytic interval, this analysis Current secondary hyperparathyroidism: multicentre observational study (COSMOS), we assessed influence 2- (midweek) or 3-day (post-weekend) dialysis interval for blood withdrawal serum levels CKD-MBD their...
Background: Epidemiologists often assess lifetime pesticide exposure by questioning participants about use of specific pesticides and associated work practices. Recently, Dosemeci colleagues proposed an algorithm to estimate average intensity from questionnaire information. We evaluated this against measured urinary concentrations for farmers who applied glyphosate (n = 48), 2,4-D 34), or chlorpyrifos 34). Methods: Algorithm scores were calculated separately based on trained field observers’...
A historical cohort study was conducted to evaluate cancer incidence among chemical workers with occupational and environmental exposure alachlor, the active ingredient in a family of pre-emergent acetanilide herbicides. The followed 943 at least 1 year cumulative employment Monsanto plant Muscatine. Iowa, from startup alachlor manufacturing process March 1968 through December 1990. Approximately 96% all were successfully traced determine their last known residence status. Eighteen diagnosed...