A5088930703- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV-related health complications and treatments
- Pharmacological Effects and Toxicity Studies
- Hepatitis C virus research
- Drug-Induced Hepatotoxicity and Protection
- Hepatitis B Virus Studies
- LGBTQ Health, Identity, and Policy
- Liver Disease Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Hormonal and reproductive studies
- Healthcare Systems and Practices
- Ocular Diseases and Behçet’s Syndrome
- HIV, Drug Use, Sexual Risk
- Sexuality, Behavior, and Technology
- Pharmaceutical Practices and Patient Outcomes
- Viral-associated cancers and disorders
- Bipolar Disorder and Treatment
- Medication Adherence and Compliance
- Health, Medicine and Society
- Herpesvirus Infections and Treatments
- Reproductive Health and Contraception
- Evaluation of Teaching Practices
Toronto General Hospital
2013-2024
University of Toronto
2014-2024
University Health Network
2014-2024
3M (United States)
2014-2024
GTx (United States)
2021
The US Oncology Network
2019
Health Net
2019
Air Liquide (United States)
2015
University of Alberta
2014
Johns Hopkins University
2008
Background: Interactions between antiretroviral (ARV) therapy and medications to treat age-related comorbidities are a growing concern in the aging HIV population. Objective: To investigate association of age with potential drug-drug interactions (PDDIs) involving ARVs. Methods: We studied ARV-treated patients attending tertiary care center. PDDIs were classified as “red flag” (contraindicated) or “orange (use caution dose adjustment). Logistic regression was used determine occurrence ≥1...
Partially wet anisotropic particles at an otherwise planar fluid interface create distortions as the bends to satisfy boundary conditions three phase contact line. Overlapping capillary interactions that depend strongly on particle shape. Since excess surface area associated with can be locally elevated certain regions near particle, resulting drive assembly in preferred orientations. In this work, arguments relating aspect ratio orientation for are developed of constant cross section....
Medication information sheetsImmunodeficiency Clinic, Toronto General Hospital www.hivclinic.ca/main/drugs_fact.html CATIE (formerly known as Canadian AIDS Information Exchange) www.catie.ca/en/fact-
Abstract Five long‐acting (LA) antiretrovirals (ARVs) are currently available in a limited number of countries worldwide for HIV‐1 prevention or treatment—cabotegravir, rilpivirine, lenacapavir, ibalizumab, and dapivirine. Implementing use LA ARVs into routine clinical practice requires significant changes to the current framework prevention, treatment, service provision. Given novelty, complexity, interdisciplinary requirements needed safely optimally utilize ARVs, consensus recommendations...
in the need for invasive mechanical ventilation or new dialysis, mortality.This study is limited by small numbers and baseline imbalance between groups.These findings suggest that remdesivir can be safely administered patients with kidney dysfunction, balancing possible risks benefits.The assessing function absence of clinical suspicion before during outpatient administration questioned.
aWomen's Health Research Institute, British Columbia (BC) Women's Hospital, Vancouver bSimon Fraser University, Faculty of Sciences, Burnaby cOak Tree Clinic, BC Hospital dFaculty Pharmaceutical UBC, eImmunodeficiency Toronto General fLeslie Dan Pharmacy, University Toronto, Ontario, Canada. Correspondence to Dr Elizabeth Marie King, 4133 Dundas Street, Burnaby, Columbia, V5C 1A9, Tel: +1 778 899 7598; e-mail: [email protected] Received 7 May, 2024 Revised 19 June, Accepted 24 This is an...
Background . Hepatitis C virus (HCV) coinfection occurs in 20–30% of Canadians living with HIV and is responsible for a heavy burden morbidity mortality. Purpose To update national standards management HCV-HIV coinfected adults the Canadian context evolving evidence accessibility effective tolerable DAA therapies. The document addresses patient workup treatment preparation, antiviral recommendations overall specific populations, drug-drug interactions. Methods A standing working group...
BackgroundPolypharmacy, defined as use of five or more medications concurrently, is associated with adverse health outcomes and people ageing HIV might be at greater risk than similar uninfected individuals. We aimed to determine whether known pairwise drug interactions (KPDIs) were admission hospital (hereafter referred hospitalisation) medication count among without after accounting for physiological frailty.MethodsIn this observational study, we collected individual-level data...
Five long-acting (LA) antiretrovirals (ARVs) are currently available in a limited number of countries worldwide for HIV-1 prevention or treatment - cabotegravir, rilpivirine, lenacapavir, ibalizumab, and dapivirine. Implementing use LA ARVs routine clinical practice requires significant changes to the current framework prevention, treatment, service provision. Given novelty, complexity, interdisciplinary requirements safe optimal ARVs, consensus recommendations on will assist clinicians...