A5060601209- Muscle activation and electromyography studies
- Prosthetics and Rehabilitation Robotics
- Hematopoietic Stem Cell Transplantation
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- CAR-T cell therapy research
- Mechanical Circulatory Support Devices
- Fluid Dynamics and Turbulent Flows
- Macrophage Migration Inhibitory Factor
- Metabolism, Diabetes, and Cancer
- Advanced Sensor and Energy Harvesting Materials
- Glycosylation and Glycoproteins Research
- Lattice Boltzmann Simulation Studies
- Robotics and Sensor-Based Localization
- Balance, Gait, and Falls Prevention
- Growth Hormone and Insulin-like Growth Factors
- Advanced battery technologies research
- Hydrogen Storage and Materials
- Target Tracking and Data Fusion in Sensor Networks
- Advanced Image and Video Retrieval Techniques
- Electrocatalysts for Energy Conversion
- Aerosol Filtration and Electrostatic Precipitation
- Stroke Rehabilitation and Recovery
- Robotic Locomotion and Control
- Iterative Learning Control Systems
City Of Hope National Medical Center
2023-2024
City of Hope
2022-2024
Beckman Research Institute
2022-2024
Xinqiao Hospital
2023
Army Medical University
2023
University of Science and Technology of China
2018-2023
Beijing University of Technology
2017-2022
Shenzhen University
2020
Northwestern Polytechnical University
2012-2013
Hebei University
2011-2012
Many previous works of soft wearable exoskeletons (exosuit) target at improving the human locomotion assistance, without considering impedance adaption to interact with unpredictable dynamics and external environment, preferably outside laboratory environments. This article proposes a novel hierarchical human-in-the-loop paradigm that aims produce suitable assistance powers for cable-driven lower limb exosuits aid ankle joint in pushing off ground. It includes two primary loop layers:...
Exoskeletons are increasingly used to assist humans in military, industry, and healthcare applications, thereby enabling individuals gain increased strength endurance. This article proposes a novel human-in-the-loop control framework for fully actuated lower limb exoskeleton with high degree-of-freedoms (DoFs), allowing users walk without crutches or other external stabilization tools. To imitate the natural motion of users, barrier energy function is utilized design strategy, where...
Soft exo-suit could facilitate walking assistance activities (such as level walking, upslope, and downslope) for unimpaired individuals. In this article, a novel human-in-the-loop adaptive control scheme is presented soft exo-suit, which provides ankle plantarflexion with unknown human-exosuit dynamic model parameters. First, the coupled formulated to express mathematical relationship between actuation system human joint. Then, gait detection approach, including timing planning, proposed....
GPU is continuing its trend of vastly outperforming CPU while becoming more general purpose. In order to improve the efficiency AES algorithm, this paper proposed a CUDA implementation Electronic Codebook (ECB) mode encoding process and Cipher Feedback (CBC) decoding on GPU. our implementation, frequently accessed T-boxes were allocated on-chip shared memory granularity that one thread handles 16 Bytes block was adopted. Finally, we achieved highest performance around 60 Gbps throughput...
More natural and intuitive control is expected to maximize the auxiliary effect of powered prosthetic leg for lower limb amputees. In order realize stable flexible walking legs in different terrains according human intention, a brain-computer interface (BCI) based on motor imagery (MI) developed. For raw electroencephalogram (EEG) signals, discrete wavelet transform (DWT) utilized extract time-frequency domain features, which are used as input signals common spatial pattern (CSP) obtain...
STAT3 deficiency (STAT3-/-) in donor T cells prevents graft-versus-host disease (GVHD), but the impact on graft-versus-leukemia (GVL) activity and mechanisms of GVHD prevention remains unclear. Here, using murine models GVHD, we show that STAT3-/- induced only mild reversible acute while preserving GVL effects against nonsusceptible lymphoblastic leukemia (ALL) a cell dose-dependent manner. depended programmed death ligand 1/programmed protein 1 (PD-L1/PD-1) signaling. In target tissues,...
Recent advances in robotics technology provide great support for robotic leg prostheses to realize full biomechanical functionalities of the contralateral leg. In order reproduce behaviors leg, this article addresses biologically inspired deadbeat control under different terrain conditions including level ground, stairs ascent, and descent. The proposed method is based on ground reactive force during walking. trajectories center-of-mass are encoded by corresponding polynomial splines. Then,...
Rapid development in robotics and bionics makes it possible for robotic leg prostheses to help amputees while imposing challenges on duplicating the motion characteristics of amputees' healthy leg. One critical problem prosthetic control is joint angle drift problem, that is, a repetitive trajectory task space cannot guarantee generated trajectories are also repetitive. In order solve this article, we propose neural-dynamics optimization generate real time. Our proposed method duplicates...
Many previous studies of soft exosuits improved human locomotion performance. However, there is no example to control a exosuit using ankle impedance adaption in assistance tasks compliantly. In this article, the human–environment interaction information exploited into control. A novel fuzzy-based optimization and method proposed provide plantarflexion for walking by changing human–robot interaction. particular, fuzzy neurodynamics developed learn unknown parameters automatically....
Human during walking can sense the joint angle and contact force between leg ground uses such information as feedback to regulate performance. To complete this motor control for amputee with prosthesis, human-in-the-loop was proposed. This method involves restoration of sensory unified gait generator. By restoring prosthesis noninvasive Functional Electrical Stimulation (nFES), subject touch-down moment, leave-off height small obstacles on ground. Then, generator converts subject's intent...
The design, control and implementation of a lower limb prosthesis with powered knee ankle for transfemoral amputees are described in this paper. Firstly, the mechanical design is introduced. Then hierarchical approach walking coordination proposed. acquires expected motion trajectory which obtained from movement physiological information amputee's healthy leg collected by Inertial Measurement Unit (IMU). Meanwhile, recognition during carried out decoding EMG signals. In order to verify its...
Most approaches to robot visual localization rely on local, global or semantic information as observation. In this paper, the combination of and is used landmark in observation model Bayesian filters. Introducing improved Gaussian Process into models with information, The GP-Localize algorithm extended high dimensional data, which means that all historical data spatiotemporal correlation achieve constant time memory for persistent outdoor can be considered by other contribution paper we...
Abstract Since Ohsawa et al. reported a biological antioxidant function of hydrogen in 2007, researchers have now shown it to exert protective effects wide range human and animal disease models. Clinical observations scientific arguments suggest that selective scavenging property H 2 cannot adequately explain the beneficial hydrogen. However, there is no experiment challenging original published data, which suggested molecular dissolved solution reacts with hydroxyl radicals cell-free...
Recently, the Graphic Processor Unit (GPU) has evolved into a highly parallel, multithreaded, many-core processor with tremendous computational horsepower and very high memory bandwidth. To improve simulation efficiency of complex flow phenomena in field fluid dynamics, CUDA-based algorithm large eddy using multiple GPUs is proposed. Our implementation adopted "collision after propagation" scheme performed propagation process by global reading transactions. The working set split up equal...
This paper proposes a trajectory generation of prosthesis to help amputee crossing over obstacles. Dynamical movement primitives (DMPs) are popular methods reproducing for learning control. In the basic DMPs, novel term obstacle is added generate in real-time. includes multiple point sources reflect spatial size Each used calculate direction relative current position. Moreover, vector and velocity considered into obstacle. Besides, DMPs can effective through parameter adjusting regardless...
To identify the association of macrophage migration inhibitory factor (MIF) gene polymorphism with susceptibility benign lymphoepithelial lesions (BLEL) lacrimal gland.A total 40 BLEL gland cases were matched healthy subjects (HS). Extraction plasma and whole blood DNA patients HS. Elisa polymerase chain reaction was used to determine in contents MIF SNP-173G>C STR -794 CATT(5-8) polymorphism, respectively.The levels significantly higher versus HS (P<0.001). The -173 G>C associated BLEL, a...
In this paper, the human ankle impedance information will be added into human-exosuit dynamic model, and then a human-in-the-loop control of soft exosuit is designed to provide plantar flexion assistance. The gradient-following betterment schemes are employed obtain desired model. scheme can an auxiliary force for push off ground in variable human-exsosuit interaction. When subject wears walks on ground, iterative learning method used give exoskeleton human-like process skills, so that it...
Most approaches to robot visual localization rely on local, global or semantic information as observation. In this paper, we use the combination of and landmark in observation model Bayesian filters. Introducing improved Gaussian Process into models with information, extend GP-Localize algorithm high dimensional data, which way filters can consider all historical data spatiotemporal correlation achieve constant time memory for persistent outdoor localization. Our another contribution is...
In this paper, an optimal controller is designed and applied to the lower-limb exoskeleton robot, which could improve robustness under nonlinear perturbations. order derive controller, we build modeling of robot simplify structure then define a cost function, because function difficult solve, so adopt approximation method approximate its value, control obtained by solving Hamiltonian equation. Finally, simulation studies are carried out. These verify that has good performance even in...