- Hydrogels: synthesis, properties, applications
- Advanced Materials and Mechanics
- Micro and Nano Robotics
- Advancements in Transdermal Drug Delivery
- Advanced Sensor and Energy Harvesting Materials
- Advanced Drug Delivery Systems
- Phytochemistry and Biological Activities
- Tissue Engineering and Regenerative Medicine
- Pancreatic function and diabetes
- Material Properties and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Cellulose Research Studies
- Bladder and Urothelial Cancer Treatments
- Characterization and Applications of Magnetic Nanoparticles
- Distributed and Parallel Computing Systems
- Electrospun Nanofibers in Biomedical Applications
- Advanced Data Processing Techniques
- Lipid Membrane Structure and Behavior
- Ginseng Biological Effects and Applications
- Nanoplatforms for cancer theranostics
- Membrane Separation Technologies
- Plant and Biological Electrophysiology Studies
- Pediatric Urology and Nephrology Studies
- Biological and pharmacological studies of plants
- 3D Printing in Biomedical Research
Johns Hopkins University
2019-2024
Beijing Forestry University
2019-2021
The distribution of periodic patterns materials with radial or bilateral symmetry is a universal natural design principle. Among the many biological forms, tubular shapes are common motif in organisms, and they also important for bioimplants soft robots. However, simple principle strategic placement 3D printed segments swelling nonswelling to achieve widely different functionalities yet be demonstrated. Here, we report design, fabrication, characterization segmented gel tubes composed an...
Due to their precisely modifiable microporosity and chemical functionality, Metal–Organic Frameworks (MOFs) have revolutionized catalysis, separations, gas storage, drug delivery, sensors. However, because of rigid brittle powder morphology, it is challenging build customizable MOF shapes with tunable mechanical properties. Here, we describe a new three-dimensional (3D) printing approach create stretchable tough hydrogel structures We formulate printable ink by combining prepolymers...
Hookworm inspired, autonomous latching on the gastrointestinal mucosa extends in vivo retention of a drug delivery device.
Subcritical water extraction (SWE) uses hot compressed as an effective solvent for both polar and nonpolar compounds has been developed environmentally benign technology natural materials. Polysaccharides one of the main ingredients in Dendrobium plants showed obvious biological activity. Thus, SWE polysaccharides obtained from nobile Lindl. was investigated this work. The response surface methodology (RSM) combined with a Box-Behnken design to evaluate influence that three independent...
The delivery of macromolecular drugs via the gastrointestinal (GI) tract is challenging as these display low stability well poor absorption across intestinal epithelium. While permeation-enhancing drug methods can increase bioavailability molecular weight drugs, effective high tight epithelial cell junctions remains a formidable challenge. Here, we describe autonomous microinjectors that are deployed in GI tract, then efficiently penetrate mucosa to deliver drug, insulin, systemic...
Untethered microrobots offer the possibility to perform medical interventions in anatomically complex and small regions body. Presently, it is necessary access upper urinary tract diagnose treat Upper Tract Urothelial Carcinoma (UTUC). Diagnostic treatment challenges include ensuring adequate tissue sampling, accurately grading disease, achieving completeness endoscopic treatment, consistently delivering medications targeted sites. This work introduces microgrippers (µ-grippers) that are...
Abstract Pulping and papermaking generate large amounts of waste in the form lignosulfonates which have limited valorized applications so far. Herein, we report a novel lignosulfonate‐based nanofiltration membrane, prepared by using polyethylenimine (PEI) sodium lignosulfonate (SL) via layer‐by‐layer (LbL) self‐assembly. As low‐cost renewable natural polyelectrolyte, SL is selected to replace synthetic polyelectrolyte commonly used conventional LbL fabrication for composite membranes. The...
You have accessJournal of UrologyCME1 May 2022MP32-14 IN VITRO TESTING OF UNTETHERED THERMAL-ACTUATED MICROGRIPPERS AS A NOVEL DIAGNOSTIC TOOL FOR UROTHELIAL TISSUE Ridwan Alam, Wangqu Liu, Ezra Baraban, Brian Matlaga, Andres Matoso, David Gracias, and Jared Winoker AlamRidwan Alam More articles by this author , LiuWangqu Liu BarabanEzra Baraban MatlagaBrian Matlaga MatosoAndres Matoso GraciasDavid Gracias WinokerJared View All Author...
Abstract The delivery of macromolecular drugs via the gastrointestinal (GI) tract is challenging. Macromolecular display low stability and poor absorption across intestinal epithelium. While permeation-enhancing drug methods can increase bioavailability molecular weight drugs, effective high tight epithelial cell junctions remains a formidable challenge. Here, we describe autonomous microinjectors that efficiently penetrate GI mucosa deliver insulin systemically. In addition, performed in...