A5032626842- Nanoplatforms for cancer theranostics
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Micro and Nano Robotics
- Photodynamic Therapy Research Studies
- SARS-CoV-2 and COVID-19 Research
- Histone Deacetylase Inhibitors Research
- Metal complexes synthesis and properties
- Lung Cancer Treatments and Mutations
- Molecular Communication and Nanonetworks
- Immunotherapy and Immune Responses
- Glycosylation and Glycoproteins Research
- Hydrogels: synthesis, properties, applications
- Rheumatoid Arthritis Research and Therapies
- Cancer Treatment and Pharmacology
- 3D Printing in Biomedical Research
- Advancements in Transdermal Drug Delivery
- Multiple Myeloma Research and Treatments
- Synthesis and biological activity
- Endoplasmic Reticulum Stress and Disease
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Research Studies
- Pharmacological Effects of Natural Compounds
- PARP inhibition in cancer therapy
- Pharmacology and Obesity Treatment
JSS Academy of Higher Education and Research
2019-2024
Johns Hopkins University
2020
Amrita Institute of Medical Sciences and Research Centre
2013-2019
Amrita Vishwa Vidyapeetham
2013-2019
Brigham and Women's Hospital
2016
Innovation Research Center
2016
Innovation Center Denmark
2016
Roswell Park Comprehensive Cancer Center
2013
Institute of Medical Sciences
2013
Hookworm inspired, autonomous latching on the gastrointestinal mucosa extends in vivo retention of a drug delivery device.
Migratory capacity of cancer plays a critical role in the process metastasis. Aberrant focal adhesions activated by phosphorylation Src kinase enables cells to anchor on its micro-environment and migrate towards biochemically favorable niche, causing Effective blocking migratory inhibiting protein kinases subsequent application cytotoxic stress may provide better therapeutic outcome. Here, we report novel core-shell nanomedicine that inhibits migration nano-shell impart reactive oxygen laser...
The present study explored anti-tubercular pyrrole derivatives against cancer targets using different in silico and vitro approaches. Initially, nineteen pyrrolyl benzohydrazide were screened a potent target PLK1 an AutoDock Vina approach. Out of the derivatives, two most C8 [N′-(4-(1H-pyrrol-1-yl) benzoyl)-3-chlorobenzohydrazide] C18 benzoyl)-4-nitrobenzohydrazide], subjected to molecular simulation analysis for 100 ns trajectory. Further, these tested A549, MCF-7, HepG2 cell lines MTT...
Abstract Triple-negative breast cancer (TNBC) is an aggressive form of occurring in 15-20% patients, with most patients relapsing on currently approved therapy. Recent studies have shown activity platinum chemotherapy this class patients. IO-125 a novel (II) chemotherapeutic agent unique coordination environment. In study, we investigated the anti-tumor pre-clinical models TNBC. The environment facilitates supramolecular assembly and releases diaminocyclohexane (DACH)-platinum sustained...