A5082633592- Mass Spectrometry Techniques and Applications
- Analytical chemistry methods development
- Heavy Metal Exposure and Toxicity
- Advanced MEMS and NEMS Technologies
- Mercury impact and mitigation studies
- Metabolomics and Mass Spectrometry Studies
- Trace Elements in Health
- Textile materials and evaluations
- Dyeing and Modifying Textile Fibers
- Analytical Chemistry and Chromatography
- Epoxy Resin Curing Processes
- Ion-surface interactions and analysis
- Heavy metals in environment
- Photonic and Optical Devices
- Mechanical and Optical Resonators
- Biofuel production and bioconversion
- Amino Acid Enzymes and Metabolism
- Advanced Cellulose Research Studies
- Microbial Community Ecology and Physiology
- Synthesis and properties of polymers
- Marine and fisheries research
- Nanofabrication and Lithography Techniques
- Enzyme Production and Characterization
- Fiber-reinforced polymer composites
- Gas Sensing Nanomaterials and Sensors
University of Technology Sydney
2016-2025
Royal Botanic Gardens, Kew
2021
Sanford Broadway Medical Center
2015-2019
Florey Institute of Neuroscience and Mental Health
2018
The University of Melbourne
2018
Memorial University of Newfoundland
2017-2018
Innovations for Poverty Action
2017
University of Ulster
2016-2017
University of Technology
2014-2015
Seoul National University
2015
The tree of life is the fundamental biological roadmap for navigating evolution and properties on Earth, yet remains largely unknown. Even angiosperms (flowering plants) are fraught with data gaps, despite their critical role in sustaining terrestrial life. Today, high-throughput sequencing promises to significantly deepen our understanding evolutionary relationships. Here, we describe a comprehensive phylogenomic platform exploring angiosperm life, comprising set open tools based 353...
Millions of individuals with malaria-like fevers purchase drugs from private retailers, but artemisinin-based combination therapies (ACTs), the only effective treatment in regions high levels resistance to older drugs, are rarely obtained through these outlets due their relatively cost. To encourage scale up ACTs, Affordable Medicines Facility – malaria is being launched subsidize price. The Government Tanzania and Clinton Foundation piloted this subsidized distribution model two Tanzanian...
Imaging of iron and dopamine by laser ablation-inductively coupled plasma-mass spectrometry reveals a risk index for parkinsonian neurodegeneration
Obesity is a high risk for multiple metabolic disorders due to excessive influx of energy, glucose and lipid, often from western based diet. Low-grade inflammation plays key role in the progression such disorders. The anti-inflammatory property gold compounds has been used treating rheumatoid arthritis clinic. Previously we found that pure nanoparticles (AuNPs, 21 nm) also possess effects on retroperitoneal fat tissue following intraperitoneal injection, by downregulating tumor necrosis...
Element response variations under different laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) operating conditions were investigated to identify important factors for selecting an internal standard (IS) quantitative elemental bio-imaging. Analytes covering a range of atomic masses and first ionisation potentials (FIP) selected investigate the signal variation with changes in spot diameter, mass bias cell sampling position. In all cases, IS improved experimental...
Calibration with matrix-matched standards remains the most practical means for producing quantitative images of trace metal distribution in tissue sections by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). A general guide assay metals brain is presented. Cortical was taken from pooled sheep brains and spiked varying approximate concentrations standard solutions Co, Cu, Fe, Mg, Mn, Sr, Se Zn. The homogenised total analyte amount accurately determined solution...
Metals have a number of important roles within the brain. We used laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) to map three-dimensional concentrations and distributions transition metals, in particular iron (Fe), copper (Cu) zinc (Zn) murine LA-ICP-MS is one leading analytical tools for measuring metals tissue samples. Here, we present complete data reduction protocol biological samples, including application pyramidal voxel registration technique reproducibly...
Elemental bio-imaging using the technological advances of ICP-QQQ-MS.
Abstract The thermal degradation of a bisphenol A‐based epoxy resin (EP 274) cured with 4,4′‐diaminodiphenyl methane (DDM) and phthalic anhydride (PA) was studied using radiochemical pyrolysis gas chromatography technique. Conclusive evidence for some the mechanisms these resins obtained by pyrolyzing samples containing various 14 C‐labelled groups analyzing products this method.
Abstract The benefits of using silk fibroin, a major protein in silk, are widely established many biomedical applications including tissue regeneration, bioactive coating and vitro models. properties such as biocompatibility controlled degradation utilized this study to formulate for the first time carriers pulmonary drug delivery. Silk fibroin particles spray dried or spray-freeze-dried enable delivery airways via dry powder inhalers. addition excipients mannitol is optimized both...
Elemental imaging using laser ablation inductively coupled plasma mass spectrometry was performed on whole leaves of the hyperaccumulating plant<italic>Noccaea caerulescens</italic>after treatments with either Ni, Zn or Cd.
Highlights•The last meal of the Iceman, a European Copper Age mummy, was reconstructed•Our multipronged approach deciphers composition and food processing•His high-fat diet supplemented with wild meat cerealsSummaryThe history humankind is marked by constant adoption new dietary habits affecting human physiology, metabolism, even development nutrition-related disorders. Despite clear archaeological evidence for shift from hunter-gatherer lifestyle to agriculture in Neolithic Europe [1], very...
Environmental toxicants are suspected to play a part in the pathogenesis of idiopathic Parkinson's disease (PD) and may underlie its increasing incidence. Mercury exposure humans is common due accelerating levels atmospheric mercury, mercury damages cells via oxidative stress, cell membrane damage, autoimmunity, mechanisms PD. We therefore compared cellular distribution tissues people with without PD who had evidence previous by being present their locus ceruleus neurons.Paraffin sections...
Multiple sclerosis and the major sporadic neurogenerative disorders, amyotrophic lateral sclerosis, Parkinson disease, Alzheimer disease are considered to have both genetic environmental components. Advances been made in finding predispositions these but it has difficult pin down agents that trigger them. Environmental toxic metals implicated neurological since human exposure is common from anthropogenic natural sources, damaging properties suspected underlie many of disorders. Questions...
We have attempted to clarify the effects of low and high levels mechanical agitation on cellulolytic activity a pure endoglucanase ( EG ) total cellulase mixture (TC) scoured bleached cotton fabric, along with effect pretreatment subsequent treatments TC. Methods used follow progress fabric include weight loss, breaking load bending hysteresis, pro duction soluble reducing sugars end groups in fibers. The results show that rate affects mechanism attack, this has implications for delivering...
In 2011, as part of a broader effort to understand organisational effectiveness, team within Oxfam GB began implementing impact evaluations on small sample projects largely focused women's empowerment. The resulting 'Women's Empowerment Effectiveness Reviews' employ quasi-experimental evaluation design, and have been undertaken in more than dozen sites over three years. This article briefly presents the Women's Reviews their short history, then focuses five key areas where approach has...