A5051281026- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Liver Disease and Transplantation
- Mitochondrial Function and Pathology
- Silk-based biomaterials and applications
- Congenital Anomalies and Fetal Surgery
- Organ Transplantation Techniques and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer therapeutics and mechanisms
- Protein Degradation and Inhibitors
- Neuroendocrine Tumor Research Advances
- Cell death mechanisms and regulation
- Congenital Diaphragmatic Hernia Studies
- ATP Synthase and ATPases Research
- Hidradenitis Suppurativa and Treatments
- Virus-based gene therapy research
- Glioma Diagnosis and Treatment
- Ocular Oncology and Treatments
- Urological Disorders and Treatments
- Peptidase Inhibition and Analysis
- Neurofibromatosis and Schwannoma Cases
- Cancer Research and Treatments
Stanford University
2018-2025
Agilent Technologies (Germany)
2024
University of California, San Diego
2024
Weatherford College
2023
Edison International (United States)
2022
Stanford Medicine
2021
Medical University of South Carolina
2021
University of Illinois Chicago
2014-2020
Palo Alto University
2018-2019
Tufts University
2014-2019
The parallel explosions of interest in streaming data, and data mining time series have had surprisingly little intersection. This is spite the fact that are typically data. main reason for this apparent paradox vast majority work on explicitly assumes discrete, whereas real valued.Many researchers also considered transforming valued into symbolic representations, nothing such representations would potentially allow to avail wealth structures algorithms from text processing bioinformatics...
<h3>Hypothesis</h3> The 6 published criteria for predicting curative parathyroid resection by means of intraoperative hormone (IOPTH) assay are not equivalent. <h3>Design</h3> Retrospective review 352 patients undergoing parathyroidectomy primary hyperparathyroidism from January 1, 1999, to December 31, 2004. We evaluated 6-month postoperative IOPTH values and serum calcium levels. <h3>Setting</h3> Tertiary referral center. <h3>Main Outcome Measures</h3> at baseline (preincision preexcision)...
Abstract The Warburg effect is the major metabolic hallmark of cancer. According to himself, consequence cell dedifferentiation. Therefore, reversing might be an approach restore differentiation in In this study, we used a mitochondrial uncoupler, niclosamide ethanolamine (NEN), activate respiration, which induced neural neuroblastoma cells. NEN treatment increased NAD+/NADH and pyruvate/lactate ratios also α-ketoglutarate/2-hydroxyglutarate (2-HG) ratio. Consequently, promoter CpG island...
Neuroblastoma tumour resection goal is maximal removal. We hypothesise that combining surgery with sustained, local doxorubicin application can control growth. injected human neuroblastoma cells into immunocompromised mouse adrenal gland. When KELLY cell-induced volume was >300 mm3, 80–90% of resected and treated as follows: instantaneous-release silk film 100 μg (100IR), controlled-release 200 (200CR) over residual bed; intravenous (100IV 200IV). Tumour measured histology analysed....
Pilonidal disease begins in puberty when males and females have different sex hormone expression. We hypothesize that differences can lead to clinical pilonidal disease. Patient demographics, Fitzpatrick skin type, hair characteristic, presentation, pain score, recurrence were recorded 2019–2022. All patients underwent regular epilation+/-pit excision. Excised pits stained for estrogen receptor, progesterone androgen receptor. 237 (110F, 127 M) followed 351±327days. Females present younger...
Neuroblastoma is the most common extracranial childhood solid tumor. Treatment of high risk tumors require intense multicycle chemotherapies, resulting in short- and long-term toxicities. Here, we present treatment an orthotopic neuroblastoma mouse model, with silk fibroin materials loaded vincristine, doxorubicin or combination as a intratumoral, sustained release system. The materials, vincristine without doxorubicin, significantly decreased tumor growth compared to drug only well...
// Risa Niemas-Teshiba 1 , Ryosuke Matsuno 1, 13 Larry L. Wang Xao X. Tang 2, 14 Bill Chiu 3 Jasmine Zeki Jeannine Coburn 4 Kimberly Ornell Arlene Naranjo 5 Collin Van Ryn Wendy B. London 6 Michael D. Hogarty 7 Julie M. Gastier-Foster 8 A. Thomas Look 9 R. Park 10 John Maris Susan Cohn 11 Robert C. Seeger 12 Shahab Asgharzadeh Naohiko Ikegaki 2 and Hiroyuki Shimada Department of Pathology Laboratory Medicine, Children's Hospital Los Angeles, University Southern California Keck School CA...
Several important time series data mining problems reduce to the core task of finding approximately repeated subsequences in a longer series. In an earlier work, we formalized idea by introducing notion motifs. Two limitations this work were poor scalability motif discovery algorithm, and inability discover motifs presence noise.Here address these novel algorithm inspired recent advances problem pattern biosequences. Our is probabilistic nature, but as show empirically theoretically, it can...
The world has seen an increase in catastrophic wildfires that have caused loss of lives, massive economic impacts from the properties and structures destroyed, negative on our environment ecosystem. A recent study by U.S. Geological Survey shows greenhouse gas emissions 2018 California is par with entire year equivalent all electricity generations combined feeding needs California.