Alessandra Guerrini

ORCID: 0000-0002-6553-3938
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry and Biological Activities
  • Phytochemicals and Antioxidant Activities
  • Piperaceae Chemical and Biological Studies
  • Traditional and Medicinal Uses of Annonaceae
  • Insect Pest Control Strategies
  • Plant biochemistry and biosynthesis
  • Seed and Plant Biochemistry
  • Phytochemical compounds biological activities
  • Drug Transport and Resistance Mechanisms
  • Phytochemistry and Bioactive Compounds
  • Enzyme Catalysis and Immobilization
  • Analytical Chemistry and Chromatography
  • Botanical Research and Applications
  • Ethnobotanical and Medicinal Plants Studies
  • Medicinal Plants and Neuroprotection
  • Algal biology and biofuel production
  • Natural Antidiabetic Agents Studies
  • Antioxidant Activity and Oxidative Stress
  • Cholesterol and Lipid Metabolism
  • Natural product bioactivities and synthesis
  • Flowering Plant Growth and Cultivation
  • African Botany and Ecology Studies
  • Agriculture, Plant Science, Crop Management
  • Allelopathy and phytotoxic interactions

University of Ferrara
2014-2023

Universidad Estatal Amazónica
2016-2017

University of Parma
2006

University of Bologna
2001

Fourteen brands of resveratrol-containing nutraceuticals were evaluated in order to verify their actual resveratrol content and control if health-promoting properties are related manufacturing quality. Products included pure capsules or multi-ingredient formulations with standardized amounts other phytochemicals. Samples analyzed for total trans-resveratrol, flavonoids, procyanidin, polyphenol the results compared declared on-label. Only five out 14 had near label values, compliant Good...

10.3390/molecules171012393 article EN cc-by Molecules 2012-10-22

Aedes aegypti , the main arbovirus vector of Yellow fever, Dengue, Chikungunya and Zika viruses, is widely distributed in tropical subtropical areas throughout world. Preventive control efforts have been implemented worldwide aimed at reducing its impact on human health. The recent reduction chemicals available for due to their negative environment health increase mosquito resistance insecticides driven research community identify evaluate sustainable alternatives synthetic insecticides. In...

10.1051/parasite/2019024 article EN cc-by Parasite 2019-01-01

This study describes the preparation, characterisation and in vitro activity of nanostructured lipid carriers (NLCs) encapsulating natural molecules with antimicrobial activity, such as plumbagin, hydroquinon, eugenol, alpha-asarone alpha-tocopherol. NLCs were prepared by melt ultrasonication method, characterised Cryo-TEM for morphology SdFFF dimensional distribution active encapsulation yields. In tests conducted on bacteria, fungi human cell cultures. demonstrated that plumbagin is...

10.1080/02652048.2017.1284276 article EN Journal of Microencapsulation 2017-01-02

Cancer chemotherapy is characterized by an elevated intrinsic toxicity and the development of drug resistance. Thus, there a compelling need for new intervention strategies with improved therapeutic profile. Immunogenic cell death (ICD) represents innovative anticancer strategy where dying cancer cells release damage-associated molecular patterns promoting tumor-specific immune responses. The roots Withania somnifera (W. somnifera) are used in Indian traditional medicine their...

10.3390/toxins8050147 article EN cc-by Toxins 2016-05-12

In this study, we performed the chemical characterization of Myrcia splendens (Sw.) DC. (Myrtaceae) essential oil from Amazonian Ecuador and assessment its bioactivity in terms cytotoxic, antibacterial, antioxidant activity as starting point for possible applicative uses. M. oil, obtained by hydro-distillation, was analyzed Gas Chromatography-Mass Spectrometry (GC-MS) Chromatography-Flame Ionization Detector (GC-FID): major components were found to be trans-nerolidol (67.81%) α-bisabolol...

10.3390/molecules22071163 article EN cc-by Molecules 2017-07-12

The chemical composition and biological activity of essential oils isolated from the leaves Siparuna aspera, macrotepala, Piper leticianum, augustum rhizome Hedychium coronarium were evaluated. These species are used medicinally in different ways by Amazonian communities that live near Kutukú mountain range. Chemical studies revealed main components for two germacrene D, bicyclogermacrene, α-pinene, δ-cadinene, δ-elemene, α-copaene β-caryophyllene; β-caryophyllene, α-(E,E)-farnesene,...

10.3390/molecules24081637 article EN cc-by Molecules 2019-04-25

Essential oils (EOs) and their vapour phase of Curcuma longa (Zingiberaceae), Cymbopogon citratus (Poaceae), Ocimum campechianum (Lamiaceae), Zingiber officinale (Zingiberaceae) cultivated plants grown in an Amazonian Ecuador area were chemically characterised by Gas Chromatography-Flame Ionization Detector (GC-FID), Chromatography–Mass Spectrometry (GC-MS), Head Space–Gas Chromatograph-Flame Detector–Mass (HS-GC-FID-MS).figure The EOs analyses led to the identification 25 compounds for C....

10.3390/antibiotics12010177 article EN cc-by Antibiotics 2023-01-15

Although cancers are characterized by the deregulation of multiple signalling pathways, most current anticancer therapies involve modulation a single target. Because enormous biological diversity cancer, strategic combination agents targeted against critical those alterations is needed. Due to their complex nature, plant products interact with numerous targets and influence several biochemical molecular cascades. The interest in further development botanical drugs has been increasing...

10.1371/journal.pone.0021544 article EN cc-by PLoS ONE 2011-06-28

In traditional Indian medicine, the crude drug Hemidesmus indicus root-commonly known as sarsaparilla-is used alone or in poly-herbal preparations for treatment of a wide range diseases. The present study focuses on cancer chemopreventive and therapeutic potential H. extracts an acute lymphoblastic leukemia cell line (CCRF-CEM). With this aim mind, we subjected roots to two subsequent extractions (hydro-alcoholic extraction soxhlet extraction). As DNA damage is important prerequisite...

10.3390/toxins10020070 article EN cc-by Toxins 2018-02-06

Wastes and by-products of plant origin are particular interest to develop a circular economy approach, which attempts turn them into resources. In this work, thirty-seven neglected matrices, including agricultural residues, pest plants, from the herbal food industry were extracted tested for their in vitro anti-tyrosinase, antioxidant, antibacterial activity against phytopathogens Pseudomonas syringae pv. ATCC 19310 Clavibacter michiganensis subsp. nebraskense 27822. Antioxidant ranged 0.3 5...

10.3390/plants12040795 article EN cc-by Plants 2023-02-10

Abstract Supercritical fluid extraction (SFE) of seeds Amaranthus caudatus (Amaranthaceae) and the use ultrasound as a co‐adjuvant in process were compared with methods traditionally used tocopherols fatty acids. The readily available equipment an adjunct to classical employed for tocols provided qualitatively acceptable results more rapidly economically. SFE gave quantitatively better yields shorter times, solvent‐free extracts obtained under conditions that minimised degradation...

10.1002/pca.651 article EN Phytochemical Analysis 2002-09-01

Seed oil of wild Amaranthus caudatus from Ecuador was analyzed for determining the tocopherol, fatty acid, and sterol contents. The data obtained were compared with analogous chemical profile seed Italian A. objective evaluating nutraceutical alimentary potential Ecuadorian matrix. Supercritical fluid ultrasound-enhanced extractions performed on both matrices. Qualitative quantitative determinations tocopherols by HPLC, whereas GC GC-MS used to determine acid composition sterols,...

10.1021/jf010385k article EN Journal of Agricultural and Food Chemistry 2001-10-04

The chemical composition of the essential oil obtained by steam distillation floral calyces Ocotea bofo Kunth (Lauraceae) was studied means GC, GC-MS, and 1H, 13C, bidimensional NMR (COSY, HSQC, HMBC). Twenty-five constituents were identified, estragole (48.7%), alpha-phellandrene (19.6%) sabinene (10.4%) found to be major components. Antimicrobial activity against six aerobic bacteria five yeasts antioxidant performed photochemiluminescence (PCL), 1,1-diphenyl-2-picrylhydrazyl (DPPH),...

10.1021/jf0605493 article EN Journal of Agricultural and Food Chemistry 2006-09-13

Abstract Background Cystic fibrosis (CF) airway pathology is a fatal, autosomal, recessive genetic disease characterized by extensive lung inflammation. After induction TNF-α, elevated concentrations of several pro-inflammatory cytokines (i.e. IL-6, IL-1β) and chemokines IL-8) are released from epithelial cells. In order to reduce the excessive inflammatory response in airways CF patients, new therapies have been developed this respect, medicinal plant extracts studied. article we...

10.1186/1471-2091-12-15 article EN cc-by BMC Biochemistry 2011-04-15

ABSTRACT Six lavender essential oils, L. angustifolia and five Lavandula x hybrida cultivars (Super Z, Abrialis, R.C., Alardii Ordinario), were evaluated from a phytochemical biological standpoint, the results computed by using multivariate data analysis. The oils analysed gas chromatography, chromatography–mass spectrometry headspace gas‐chromatography. Multivariate analyses (principal component analysis) identified three main clusters among represented 1,8‐cineole, linalyl acetate...

10.1002/ffj.3145 article EN Flavour and Fragrance Journal 2013-02-25

Nowadays, data concerning the composition of Caryodendron orinocense Karst. (Euphorbiaceae) and Bactris gasipaes Kunth (Arecaceae) seed oils are lacking. In light this fact, in paper fatty acids unsaponifiable fraction have been determined using GC-MS, HPLC-DAD (Diode Array Detector), NMR approaches possible future applications preliminary investigated through estimation antioxidant activity, performed with DPPH test. For C. linoleic acid (85.59%) was main component, lauric (33.29%) myristic...

10.5650/jos.ess14007 article EN Journal of Oleo Science 2014-01-01
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