Jason Labuschagne

ORCID: 0000-0002-6567-0131
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About
Contact & Profiles
Research Areas
  • Glioma Diagnosis and Treatment
  • Cerebrospinal fluid and hydrocephalus
  • Vagus Nerve Stimulation Research
  • Neurological disorders and treatments
  • Voice and Speech Disorders
  • Global Health and Surgery
  • EEG and Brain-Computer Interfaces
  • Head and Neck Surgical Oncology
  • Meningioma and schwannoma management
  • Tracheal and airway disorders
  • Neuroblastoma Research and Treatments
  • Craniofacial Disorders and Treatments
  • Surgical Simulation and Training
  • Fetal and Pediatric Neurological Disorders
  • Heart Rate Variability and Autonomic Control
  • Vascular Malformations Diagnosis and Treatment
  • Advances in Oncology and Radiotherapy
  • Peripheral Neuropathies and Disorders
  • Facial Trauma and Fracture Management
  • Transcranial Magnetic Stimulation Studies
  • Chromatin Remodeling and Cancer
  • Teratomas and Epidermoid Cysts
  • Cardiac Arrhythmias and Treatments
  • Neurofibromatosis and Schwannoma Cases
  • Global Health Workforce Issues

Nelson Mandela Academic Hospital
2019-2025

University of the Witwatersrand
2019-2025

Netcare Unitas Hospital
2019-2020

Stony Brook University
2020

Neurological Surgery
2020

Abstract Objective Vagus nerve stimulation (VNS) is an established therapy for drug‐resistant epilepsy (DRE) and indicated implantation on the left vagus nerve‐only. In rare cases right‐sided VNS may be only option. With seven published in literature, data safety effectiveness of very limited. Methods An anonymous 38‐item questionnaire was sent to expert surgeons implanting DRE. The questions covered demographics clinical characteristics, reason both neurological surgical outcomes VNS....

10.1002/acn3.52312 article EN cc-by-nc-nd Annals of Clinical and Translational Neurology 2025-02-03

Vagus nerve stimulation (VNS) has become a promising therapy especially for drug resistant epilepsy and other pathologies. Side effects or missing therapeutic success are observed due to cuff electrodes that too narrow wide. Preoperative high-resolution ultrasound is used evaluate the size of cervical vagus (CVN) estimate VNS. It remains unclear how precise reflects CVN dimensions, which been objective this study. cross-sections diameters were investigated in 23 sides from 12 bodies, using...

10.1038/s41598-023-27894-9 article EN cc-by Scientific Reports 2023-01-17

There is a growing body of literature supporting the use 5-aminolevulinic acid (5-ALA) in pediatric population, however, its still considered "off label" this setting. In retrospective study, we report our experience using 5-ALA patients with focal brainstem gliomas (BSGs).Patients younger than 16 years presenting newly diagnosed BSG that was nature were suitable for treatment 5-ALA-assisted surgery. Exclusion criteria included MRI features suggestive diffuse intrinsic pontine glioma. A...

10.25259/sni_246_2020 article EN cc-by-nc-sa Surgical Neurology International 2020-10-08

<b><i>Background:</i></b> 5-aminolevulinic acid (5-ALA) use is well established in the resection of adult high-grade gliomas. There growing interest its usefulness paediatric population. The potential benefit 5-ALA-guided motivated our unit to offer protocol as off-label use. <b><i>Objective:</i></b> determine if 5-ALA guided was routinely useful and offered increased gross total (GTR) results. <b><i>Methods:</i></b>...

10.1159/000511289 article EN Pediatric Neurosurgery 2020-01-01

Early suturectomy with a rigid endoscope followed by orthotic cranial helmet therapy is an accepted treatment option for single-suture craniosynostosis. To the authors' knowledge, flexible endoscope-assisted suture release (FEASR) has not been previously described. Presented herein their experience FEASR of isolated sagittal craniosynostosis.A retrospective analysis health records patients who had undergone between March 2018 and December 2020 was performed. Patients under age 6 months...

10.3171/2022.9.peds22227 article EN Journal of Neurosurgery Pediatrics 2022-10-14

Understanding of the epidemiology and biology pediatric CNS tumors has advanced dramatically over last decade; however there remains a discrepancy in understanding epidemiologic data clinical capacity between high- lower-income countries.We collected analyzed hospital-level burden capacity-oriented from neurosurgical oncology units at 7 referral hospitals Sub-Saharan Africa (SSA).A cross sectional epidemiological survey was conducted using REDCap SSA sites, capturing 3-month aggregate for...

10.3389/fonc.2023.1257099 article EN cc-by Frontiers in Oncology 2023-11-01

Awake craniotomy is a useful surgical approach to identify and preserve eloquent areas during tumour resection, surgery for arteriovenous malformation resections resective epilepsy surgery. With decreasing age, child's ability cooperate mange an awake becomes increasingly relevant. Preoperative screening essential the child who can undergo procedure safely. Case Description. A 11-year-old female patient presented with in her right motor cortex, presumed be dysembryoplastic neuroepithelial...

10.1155/2020/6902075 article EN cc-by Case Reports in Anesthesiology 2020-07-06

Left sided non-recurrent laryngeal nerves (NRLN) are very rarely observed during surgery in the head and neck region. Arising directly from cervical aspect of vagus nerve, NRLN lies a vulnerable position distant its normal location. NRLNs normally associated with embryological branchial arch aberrations subsequent vascular anomalies. The anomalous course makes it more susceptible to injury Knowledge this anatomical variant will reduce potential for resultant vocal cord paralysis. During...

10.3390/medicina56100489 article EN cc-by Medicina 2020-09-23

OBJECTIVE Wide disparities in neurosurgical oncology care and treatment outcomes exist globally despite recent improvements diagnostics cancer therapy. To better understand the challenges to low-resource settings, authors collected data on national capacity hospital diagnostic across 7 referral hospitals countries sub-Saharan Africa (SSA). METHODS In April 2023, a 42-item self-administered questionnaire was distributed partner neurosurgeons at centers via REDCap provide country-...

10.3171/2024.3.jns232654 article EN Journal of neurosurgery 2024-06-01

Abstract BACKGROUND Wide disparities in neurosurgical-oncologic care and treatment outcomes exists globally despite recent improvements diagnostics cancer therapy. To better understand the challenges to low resource settings, we collected data on national neurosurgery capacity hospital diagnostic across 7 referral hospitals countries Sub-Saharan Africa (SSA). METHODS A 42-item self-administered questionnaire was distributed partner neurosurgeons at sites via REDCap April 2023 provide country...

10.1093/noajnl/vdae147.031 article EN cc-by-nc Neuro-Oncology Advances 2024-10-01

ABSTRACT Epidermoid cysts are rare lesions of the central nervous system, representing 1-2% all intracranial tumours. These mass typically found in parasellar region or cerebellopontine angle. As far as we aware only 15 cases an intrinsic brainstem epidermoid have been reported pediatric population to date. We report a case which 8-year-old male patient with was misdiagnosed and treated diffuse pontine glioma (DIPG). The child subsequently referred our unit failing response treatment at...

10.18772/26180197.2020.v2n3a15 article EN Wits Journal of Clinical Medicine 2020-01-01

Background: Traditionally, human coenurosis has been ascribed to Taenia multiceps while neurocysticercosis attributed solely solium infection. Historically, however, the identification and differentiation of cestodal infection was primarily based on inaccurate morphological criteria. With increasing availability molecular methods, accuracy larval cestode species improved, not typically associated with central nervous system (CNS) are now being identified as aetiological agents. Case report:...

10.3390/tropicalmed7120405 article EN cc-by Tropical Medicine and Infectious Disease 2022-11-29

ABSTRACT South African legal and ethical guidelines direct health-care professionals to perform their duties in a manner that is acceptable within society. In Africa, there no minimum defined training or accreditation required intraoperative neuromonitoring (IONM) nor registration with the Health Professionals Council of Africa (HPCSA) prerequisite. It therefore important explore aspects this practice, particularly, since patients undergoing IONM are often vulnerable need extra protection....

10.18772/26180197.2021.v3n2a7 article EN Wits Journal of Clinical Medicine 2021-01-01

INTRODUCTION: Understanding of the epidemiology and biology pediatric central nervous system (CNS) tumors has advanced dramatically over last decade; however there remains a discrepancy in understanding epidemiologic clinical capacity-oriented data between high income low middle- or low-income countries. METHODS: A cross sectional epidemiological survey was conducted to determine incidence, diagnosis, management, follow-up paradigm for CNS using REDCap. The administered neurosurgeons at...

10.1227/neu.0000000000002375_529 article EN Neurosurgery 2023-03-16

Background: Wide disparities in neurosurgical-oncologic care and treatment outcomes exists globally despite recent improvements diagnostics cancer therapy. To better understand the challenges to low resource settings, we collected data on national neurosurgery capacity hospital diagnostic across 7 referral hospitals countries Sub-Saharan Africa (SSA).Method: A 42-item self-administered questionnaire was distributed partner neurosurgeons at centers via REDCap April 2023 provide country-...

10.2139/ssrn.4634796 preprint EN 2023-01-01
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