A5076880432- Blood Pressure and Hypertension Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Parkinson's Disease Mechanisms and Treatments
- Gout, Hyperuricemia, Uric Acid
- Neurological disorders and treatments
- Nutritional Studies and Diet
- Atrial Fibrillation Management and Outcomes
- Alcohol Consumption and Health Effects
- Liver Disease Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Genetic Neurodegenerative Diseases
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Neurological and metabolic disorders
- Cerebrospinal fluid and hydrocephalus
- Metabolism, Diabetes, and Cancer
- Health Promotion and Cardiovascular Prevention
- Cardiac Arrhythmias and Treatments
- Neurological diseases and metabolism
- Diet and metabolism studies
- Smoking Behavior and Cessation
- Muscle and Compartmental Disorders
- Chronic Kidney Disease and Diabetes
- Indoor Air Quality and Microbial Exposure
- Antiplatelet Therapy and Cardiovascular Diseases
Fukuoka University
2017-2025
Mayo Clinic in Florida
2023-2025
Kansai Medical University
2023
Kobe University
2023
Jacksonville College
2023
The second consensus criteria in 2008 have been used diagnosing multiple system atrophy (MSA). International Parkinson and Movement Disorder Society (MDS) proposed new diagnostic for MSA 2022. This study aimed to compare the accuracy between these 2 validate clinical utility of newly MSA.
Abstract In this study, we aimed to separately evaluate the relationship between waist circumference and incidence of hyperuricemia in men women general Japanese population. We performed a population-based longitudinal study using data from annual health examination residents Iki City, Japan. A total 5567 participants without at baseline were included analysis. The placed into groups according tertile circumference. outcome was incident (uric acid > 416 µmol/L [7.0 mg/dL]). investigated...
It has been suggested that non-fasting triglyceride (TG) concentrations may be useful in predicting various diseases. However, current epidemiological evidence focuses mainly on the effects of fasting TG concentrations. The aim this study was to investigate effect and levels new-onset hyperuricemia (HUA) general Japanese population. This is a population-based retrospective cohort (ISSA-CKD study); it included 5,576 participants without HUA at baseline between 2008 2019. Participants were...
Several studies have shown that idiopathic normal-pressure hydrocephalus (iNPH) can mimic other neurodegenerative disorders, particularly progressive supranuclear palsy (PSP). In this study, we investigated iNPH clinical and neuroimaging features in patients with autopsy-confirmed PSP or Lewy body disease (LBD) by assessing the normal pressure (NPH) triad of symptoms imaging disproportionately enlarged subarachnoid-space (DESH) Evans index (EI) on antemortem MRI scans. Among our study...
Objectives This study aimed to clarify the relationship between white blood cell (WBC) count and hypertension in general Japanese population. Methods We conducted a population-based retrospective cohort using annual health check-up data of residents Iki City, Nagasaki Prefecture, Japan. A total 2935 participants without at baseline were included present analysis. WBC counts classified as tertile 1 (<4700/μL), 2 (4700–5999/μL), 3 (≥6000/μL). The outcome was incident (blood pressure ≥140...
Long-term levodopa treatment in patients with Parkinson's disease (PwPD) often causes motor fluctuations, which are known to affect their quality of life (QOL). These fluctuations may be accompanied by non-motor symptoms. There is no consensus on how QOL.This was a single-center, retrospective study and included 375 who visited the neurology outpatient department Fukuoka University Hospital between July 2015 June 2018. All were evaluated for age, sex, duration, body weight, symptoms Movement...
Both body mass index (BMI) and waist circumference (WC) are associated with diabetes risk, the difference between them in predictive ability for is still contentious. We conducted a population-based study to investigate compare association of by sex. This included total 4754 subjects aged 40–80 years no at baseline 2008 2017. Using multivariate Cox proportional hazards models, we calculated hazard ratios according tertiles BMI or WC. Harrell's C statistics was applied assess models using WC...
Background: We investigated whether eating speed was associated with the incidence of diabetes in a Japanese general population. Methods: A total 4853 individuals without at baseline were analyzed. Self-reported categorized as slow, medium, and fast on basis questionnaire responses. The study outcome diabetes. Results: After an average follow-up period 5.1 years, 234 developed per 1000 person-years 4.9 slow group, 8.8 medium 12.5 respectively (*** p < 0.001 for trend). HRs 1.69 (95%CI...
Introduction: Breakfast-skipping habits are associated with adverse health outcomes including coronary heart disease, metabolic syndrome and diabetes mellitus. However, it remains uncertain whether skipping breakfast affects chronic kidney disease (CKD) risk. This study aimed to examine the association between progression of CKD. Methods: We retrospectively conducted a population-based cohort using data from Iki City Epidemiological Study Atherosclerosis Chronic Kidney Disease (ISSA-CKD)....
Background This large-scale observational study on negative events in a real-world setting investigated Japanese patients with atrial fibrillation who were not anticoagulants. aims to evaluate the incidence of ischemic stroke and bleeding (intracranial hemorrhage, gastrointestinal bleeding, others) based CHA2DS2-VASc scores anticoagulated. Methods Results We used health checkups insurance claim data from organization. Altogether, 9733 prescribed anticoagulation during their follow-up...
Background: There is uncertainty surrounding the causal relationship between serum uric acid and hypertension. The aim was to investigate association prevalence of hypertension in a general population Japanese. Methods: This population-based cross-sectional study using health check-up data residents Iki City, Nagasaki Prefecture, Japan. A total 7,484 participants aged 30 years or older were included this study. Serum classified into four groups: group 1 (< 357 µmol/L 6 mg/dL)), 2 (357 - 415...
Among patients with atrial fibrillation, the risks of ischaemic stroke and systemic embolism (IS/SE) are high even effective anticoagulation. Using large-scale, real-world data from Japan, this study aims to clarify residual IS/SE attributable modifiable risk factors among fibrillation who taking oral anticoagulants.The design we employed was a retrospective cohort. Health check-ups insurance claims Japanese health companies were accumulated January 2005 June 2017. We identified 11 848...
Objective We aimed to clarify the relationship between serum alanine transaminase (ALT) levels and incidence of new-onset diabetes in a Japanese general population. Setting Population-based retrospective cohort study using annual health check-up data for residents Iki City, Nagasaki Prefecture, Japan. Participants A total 5330 individuals (≥30 years old) without at baseline were analysed. Primary secondary outcome measures Serum ALT determined an enzymatic method classified into...
We aimed to investigate the association between serum uric acid (SUA) level and development of hypertension as well interaction effect chronic kidney disease (CKD) on this relationship in general Japanese population. included 7895 participants aged ≥30 years from ISSA-CKD study, a population-based retrospective cohort study that used annual health check-up data residents Iki Island, Japan. After exclusion 1881 with l < 1-year follow-up, 2812 at baseline, 165 missing information SUA, total...
Constipation is one of the most common non-motor symptoms in multiple system atrophy (MSA); however, it has not been evaluated according to standard diagnostic criteria for constipation patients with MSA. We characteristics MSA by using Rome (Rome III), which validated and widely used gastrointestinal disorders. Fifty-one (29 female) were enrolled study. Based on III criteria, was diagnosed 29 (56.9%); irritable bowel syndrome detected. Thirty-seven (72.5%) aware their constipation. The...
BACKGROUND: Nicotine concentration in hair is a useful marker of tobacco exposure. Detection nicotine the non-smokers indicates passive smoking. Accurate measurement among active and smokers can help smoking cessation programs or designed to prevent sec ondhand smoke OBJECTIVE: To establish, using high-performance liquid chromatography-ultraviolet detection (HPLC/UV), cut-off value distinguish from smokers. METHODS: Hair samples were collected randomly chosen Japanese men (n= 192) between...
Abstract The aim of this study was to investigate the association between pulse pressure (PP) and chronic kidney disease (CKD) progression among general population in Japan. We conducted a population-based cohort residents Iki Island, Nagasaki, Japan, from 2008 2018. identified 1042 participants who had CKD (estimated glomerular filtration rate(eGFR) < 60 mL/min/1.73 m 2 or presence proteinuria) at baseline. Cox’s proportional hazard model used evaluate PP CKD. During 4.66-year mean...