- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Plant Toxicity and Pharmacological Properties
- Phytochemicals and Antioxidant Activities
- Phytochemical compounds biological activities
- Antimicrobial Peptides and Activities
- Research in Cotton Cultivation
- Medicinal Plant Extracts Effects
- Botanical Research and Chemistry
- Phytochemistry Medicinal Plant Applications
- Plant biochemistry and biosynthesis
- Reproductive Biology and Fertility
- Phytochemistry and Biological Activities
- Toxoplasma gondii Research Studies
- Cancer Treatment and Pharmacology
- Veterinary medicine and infectious diseases
- Fungal Biology and Applications
- Synthesis and Biological Activity
- Pediatric health and respiratory diseases
- Trypanosoma species research and implications
- Ovarian function and disorders
- Reproductive Health and Technologies
- Respiratory viral infections research
- Cancer therapeutics and mechanisms
- Bee Products Chemical Analysis
Hospital Ana Nery
2024
Universidade Federal da Bahia
2022-2024
Universidade Federal do Rio Grande do Sul
2012-2019
Universidade Federal de Santa Maria
2008
IIT Research Institute
1979
New medicines for the treatment of bacterial biofilm formation are required. For this reason, study shows in vitro activity betulinic acid (BA), ursolic (UA) and their twenty derivatives against planktonic cells (gram-positive pathogens: Enterococcus faecalis, Staphylococcus aureus epidermidis). We evaluated antibiofilm (through crystal violet method), as well antibacterial via absorbance (OD600) at concentrations 5, 25 100 µM. Likewise, cytotoxicity all compounds was on a kidney African...
α-Curcumene was isolated from the fresh aerial parts of Senecio selloi Spreng. DC. and its activity against bacteria, yeasts an alga inspected by applying microdilution method. The strongest effect manifested Saccharomyces cerevisiae with estimated values MIC MFC 0.8 mg/mL. α-curcumene synergism in concentrations 1 mM 5 mM, respectively, selected antibiotics (ciprofloxacin, imipenem, ceftazidim a combination amoxicillin clavulanic acid) investigated Staphylococcus aureus, Escherichia coli,...
Abstract The human respiratory syncytial virus (hRSV) is a leading cause of hospitalization due to acute lower infection especially in infants and young children, sometimes causing fatal cases. monoclonal antibody palivizumab one the available options for preventing this virus, at moment there are several hRSV vaccine trials underway. Unfortunately, only drug option treat ribavirin, which can be used severe high‐risk For reason, new medicines needed and, context, triterpenes their...
Abstract Procedures for preparing texturized cottonseed protein and isolate. In either case the free gossypol is effectively reduced. Further work in progress especially on
This work consists of a systematic review the literature related to plant species cataloged in Parque das Dunas, Salvador-BA, region acclaimed by title Atlantic Forest biosphere reserve UNESCO (United Nations Educational, Scientific and Cultural Organization). We included studies containing data on pharmacological activity, phytochemical toxic profile species, from PUBMED, SCIELO SCIENCE DIRECT databases, Portuguese English, without delimited period. The scientific names thirty were used as...
Natural products are the most important source of antitumor and anti-infective agents, at same time, they can have problems related to their physic-chemical parameters resulting in poor pharmacokinetic. Semi- synthesis promotes structural changes which improve activity pharmacokinetic properties decreases toxicity. The aim this review is demonstrate importance semi- obtain new drugs as antineoplastics (ixabepilone, temsirolimus, everolimus, vinflunine trabectine), antimicrobials (telavancin,...
Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii e Plasmodium spp. apresentam mecanismos de patogenicidade que contribuem para a sobrevivência intracelular. O objetivo desta revisão é discutir os patogênicos envolvidos na relação parasito-hospedeiro. Cada um desses protozoários possui específicos invasão, formação do vacúolo parasitóforo, desenvolvimento, obtenção nutrientes evasão sistema imune. Dentre fatores moleculares virulência destacam-se as mucinas, glicoproteína 160 cruzipaína...