A5083996209- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemistry Medicinal Plant Applications
- Phytochemicals and Antioxidant Activities
- Metabolomics and Mass Spectrometry Studies
- Traditional and Medicinal Uses of Annonaceae
- Natural Antidiabetic Agents Studies
- Bioactive Compounds and Antitumor Agents
- Phytochemical compounds biological activities
- Analytical Chemistry and Chromatography
- Plant biochemistry and biosynthesis
- Phytochemistry and biological activity of medicinal plants
- Insect Pest Control Strategies
- Sesquiterpenes and Asteraceae Studies
- Microbial Natural Products and Biosynthesis
- Banana Cultivation and Research
- Insect and Pesticide Research
- Mass Spectrometry Techniques and Applications
- Bee Products Chemical Analysis
- Plant Toxicity and Pharmacological Properties
- Allelopathy and phytotoxic interactions
- Biochemical Analysis and Sensing Techniques
- Piperaceae Chemical and Biological Studies
- Bacterial biofilms and quorum sensing
Universidade Federal de Mato Grosso do Sul
2016-2025
Universidade Federal do Rio Grande do Sul
2002-2024
Faculdade de Tecnologia e Ciências
2024
Universidade Federal da Grande Dourados
2024
Universidade Zambeze
2024
Instituto Federal Goiano
2024
Universidade de São Paulo
2010-2023
Natura (Brazil)
2011-2023
Centro de Espectrometria de Massas Aplicada (Brazil)
2023
Sociedade Brasileira de Química
2023
Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging curated database of >60,000 monocultures, users can known and unknown MS/MS spectra link them to their respective producers via fragmentation patterns. Identification microbe-derived metabolites relative without priori knowledge will vastly enhance the understanding microorganisms’ role ecology human health.
Plants produce many compounds that are biologically active, either as part of their normal program growth and development or in response to pathogen attack stress. Traditionally, Anadenanthera colubrina, Commiphora leptophloeos Myracrodruon urundeuva have been used by communities the Brazilian Caatinga treat several infectious diseases. The ability impair bacterial adhesion represents an ideal strategy combat pathogenesis, because its importance early stages process; thus, search for...
Despite many advances, biomaterial-associated infections continue to be a major clinical problem. In order minimize bacterial adhesion, material surface modifications are currently being investigated and natural products possess large potential for the design of innovative coatings. We report bioguided phytochemical investigation Pityrocarpa moniliformis characterization tannins by mass spectrometry. It was demonstrated that B-type linked proanthocyanidins-coated surfaces, here termed Green...
Lychnophora salicifolia plants collected from four different places in Brazil (three states: Goias, Minas Gerais and Bahia) revealed a conserved accumulation of vicenin-2, di-C-glycosyl flavonoid. Quantitative studies by UPLC-MS/MS showed high concentration vicenin-2 leaves sixty specimens six species. So the tissue distributions were evaluated wild (Asteraceae) laser based imaging mass spectrometry (IMS) to propose its possible functions for species analyzed. Mass spectrometric that unlike...
Geopropolis is a resin mixed with mud, produced only by stingless bees. Despite being popularly known for its medicinal properties, few scientific studies have proven biological activities. In this context, the objective of study was to determine chemical composition and antioxidant, anti-inflammatory, antimutagenic antimicrobial activities Melipona orbignyi geopropolis. The hydroalcoholic extract geopropolis (HEGP) prepared determined high performance liquid chromatography coupled diode...
A series of 28 compounds, 3-nitro-1
In most species of social insect the queen signals her presence to workers via pheromones. Worker responses pheromones include retinue formation around queen, inhibition cell production and suppression worker ovary activation. Here we show that signal Brazilian stingless bee Friesella schrottkyi is a mixture cuticular hydrocarbons. Stingless bees are therefore similar ants, wasps bumble bees, but differ from honey in which queen's mostly comprises volatile compounds originating mandibular...
Stryphnodendron adstringens (Mart.) Coville (Fabaceae) is a tree species native to the Brazilian Cerrado commonly known as barbatimão. In traditional medicine, decoctions or infusions of stem bark this plant are used in treatment several diseases. The objective study was analyze chemical composition aqueous extracts (SAAE) prepared from assess their antioxidant activity and anticancer effects well characterize cell death mechanisms against murine B16F10Nex-2 melanoma cells. From SAAE, gallic...
The Musa x paradisiaca L. inflorescence, known as banana blossom or heart, is used in traditional medicine for the treatment of diabetes mellitus. Aim study: aim study was to investigate antidiabetic activity aqueous extracts and fractions prepared from bracts flowers streptozotocin (STZ)-induced diabetic rats chemically characterize extracts. Standard flowers, bracts, their were chemical composition determined tentatively by high-performance liquid chromatography coupled diode-array...
The chemodiversity of plants is a valuable resource for drug discovery, and its combination with modern approaches can reduce the time consumption bioactive metabolite discovery. This study aimed to evaluate chemical constituents from 18 plant species different families against leukemia cancer cells application statistical analysis metabolomic data molecular networking prediction metabolites. samples, extracted by an accelerated solvent extractor using ethanol water 7:3 (v/v), were analyzed...
Herpes simplex virus infections persist throughout the lifetime of host and affect more than 80 % humans worldwide. The intensive use available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting search for new antiherpetic agents. Although diverse bioactivities have been identified in Schinus terebinthifolia, its antiviral activity not attracted much attention. present study evaluated effects a crude hydroethanolic extract from stem bark S....
Doxorubicin (DOX) is an efficient chemotherapeutic agent, but its clinical application limited by cardiotoxicity associated with increased oxidative stress. Thus, the combination of DOX and antioxidants has been encouraged. In this study, we evaluated (I) chemical composition antioxidant capacity aqueous extracts from Guazuma ulmifolia stem bark (GUEsb) leaves (GUEl) in 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenging, 2,2 ′ ‐azobis(2‐amidinopropane) dihydrochloride‐ (AAPH‐) or...
Fruits are sources of bioactive compounds that responsible for several biological activities. Therefore, this study aimed to identify the chemical composition pulp Brazilian Savanna fruit Dipteryx alata; evaluate its toxic effects, influence on life expectancy nematode Caenorhabditis elegans, and antioxidant activities in vitro vivo; describe mechanisms involved. The identified include phenols, terpenes, fatty acid derivatives, vitamins, a carboxylic acid. activity was demonstrated by...