A5011970299- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Ultrasound in Clinical Applications
- Otitis Media and Relapsing Polychondritis
- Radiology practices and education
- Systemic Sclerosis and Related Diseases
- Musculoskeletal Disorders and Rehabilitation
- Autoimmune and Inflammatory Disorders Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Innovations in Medical Education
- Urticaria and Related Conditions
- Radiation Dose and Imaging
- Psoriasis: Treatment and Pathogenesis
- Sarcoidosis and Beryllium Toxicity Research
- Renal Diseases and Glomerulopathies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Practices and Rehabilitation
- Cancer Immunotherapy and Biomarkers
- Peripheral Artery Disease Management
- Eosinophilic Disorders and Syndromes
- Pain Management and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Retinal and Optic Conditions
University Hospital Bonn
2018-2025
University of Bonn
2018-2025
Stuttgart Observatory
2022
Inter 3
2022
University of Graz
2020
Charité - Universitätsmedizin Berlin
2020
Immanuel Krankenhaus
2015-2018
Center for Rheumatology
2018
Asklepios Kliniken Bad Abbach
2012-2014
RWTH Aachen University
2012
To define the elementary ultrasound (US) lesions in giant cell arteritis (GCA) and to evaluate reliability of assessment US according these definitions a web-based exercise.Potential normal abnormal findings temporal extracranial large arteries were retrieved by systematic literature review. As subsequent step, structured Delphi exercise was conducted involving an expert panel Outcome Measures Rheumatology (OMERACT) Large Vessel Vasculitis Group agree appearance key vasculitis arteries. The...
To evaluate the intima-media thickness (IMT) of arteries involved in GCA for determining cut-off values.Forty newly diagnosed patients a fast-track clinic and 40 age- sex-matched controls were included. IMT measurement was performed at or within 24 h after diagnosis. The common superficial temporal with their frontal parietal branches facial bilaterally examined 10-22 MHz probe axillary artery 6-18 probe. Receiver operating characteristics analysis estimating values.The mean age 72 years...
To develop an Outcome Measures in Rheumatology (OMERACT) ultrasonography score for monitoring disease activity giant cell arteritis (GCA) and evaluate its metric properties.The OMERACT Instrument Selection Algorithm was followed. Forty-nine members of the large vessel vasculitis working group were invited to seven Delphi rounds. An online reliability exercise conducted using images bilateral common temporal arteries, parietal frontal branches as well axillary arteries from 16 patients with...
It is known that giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) often occur together. So far, the prevalence of GCA in newly diagnosed PMR patients has not been evaluated a prospective ultrasound study.The aim this study was to assess using vascular with PMR.A consecutive cohort prospectively for presence use systematic musculoskeletal examination.Overall, 60 were enrolled. Symptoms laboratory findings collected. All underwent shoulder hip joints, evaluating facial, temporal,...
Abstract Individuals with ultrarare disorders pose a structural challenge for healthcare systems since expert clinical knowledge is required to establish diagnoses. In TRANSLATE NAMSE, 3-year prospective study, we evaluated novel diagnostic concept based on multidisciplinary expertise in Germany. Here present the systematic investigation of phenotypic and molecular genetic data 1,577 patients who had undergone exome sequencing were partially analyzed next-generation phenotyping approaches....
Objective. To test the reliability of Outcome Measures in Rheumatology Clinical Trials (OMERACT) consensus-based ultrasound definitions for normal and vasculitic temporal axillary arteries patients with giant cell arteritis (GCA) controls. Methods. A preliminary 1-day meeting a full 3-day fulfilling OMERACT Ultrasound Group guidelines were held. Temporal examined at 2 timepoints by 12 sonographers on 4 GCA The aim was to inter- intrareader findings, halo sign, compression sign. In both...
Point-of-care ultrasound (POCUS) is rapidly gaining ground within different areas of applications. Despite the high and increasing relevance ultrasound, availability structured training programs in medical schools still limited. Therefore, many doctors keep acquiring all their skills throughout postgraduate training. As a result, new residents lack theoretical practical abilities that are critical everyday clinical practice. In order to improve this, we created implemented complete...
Abstract Introduction Prenatal lower urinary tract obstruction (LUTO) is a rare and challenging condition with potential severe morbidity mortality. shunting methods, specifically vesicoamniotic (VAS) fetal cystoscopy, aim to manage this condition. However, comprehensive education training are hindered by the rarity of LUTO. To address gap, we present low‐cost 3D‐printed ultrasound model for VAS in LUTO fetuses. The study was evaluate haptic fidelity model. Material Methods Ultrasound images...
Rheumatologists are increasingly utilizing ultrasound for suspected giant cell arteritis (GCA) or Takayasu (TAK). This enables direct confirmation of a diagnosis within the examination room without further referrals. can ask additional questions and explain findings to their patients while performing ultrasound, preferably in fast-track clinics prevent vision loss. Vascular vasculitis was recently integrated into rheumatology training Germany. New European Alliance Associations Rheumatology...
The delivery of healthcare from a distance, also known as telemedicine, has evolved over the past 50 years, changing way is delivered globally. Its integration into numerous domains permitted high-quality care that transcends obstacles geographic lack access to health providers, and cost. Ultrasound an effective diagnostic tool its application within telemedicine advanced substantially in recent particularly high-income settings low-resource areas. literature Pubmed 1960–2020 was assessed...
Abstract Background Glucocorticoids (GC) are the standard treatment for giant cell arteritis (GCA), even though they associated with adverse side effects and high relapse rates. Tocilizumab (TCZ), an interleukin-6 receptor antagonist, has shown promise in sustaining remission reducing cumulative GC dosage, but it increases risk of infections is expensive. After discontinuation TCZ, only about half patients remain remission. Additionally, few studies have been conducted looking at...
A German expert committee recommends defining fast-track clinics (FTC) for the acute diagnosis of giant cell arteritis (GCA) as follows: easy and prompt reachability at least on weekdays, scheduling appointments ideally within 24 h, examination by a specialist with GCA expertise, ≥ 2 experts per FTC, 50 patients suspected year, sonologists 300 (≥ 50) temporal axillary artery examinations, adherence to standard operating procedures, availability an 18 15) MHz lower frequency linear ultrasound...
Abstract Objectives The objective of this study was to prospectively evaluate the diagnostic efficacy transorbital ultrasound (TOS) in patients newly diagnosed with giant cell arteritis (GCA), presenting visual symptoms. Methods Patients diagnosed, untreated GCA were examined using TOS, assessing central retinal artery flow velocity [peak systolic (PSV), end-diastolic (EDV), resistance index (RI)], and optic nerve diameter (OND). Vascular conducted superficial temporal arteries, their...
Introduction:Cancer rates are rising in low-and middle-income countries.While pointof-care ultrasound is now available globally and could serve to mitigate against this rise, its use diagnosing cancers inconsistent lower-resourced healthcare contexts.This proof-of-concept study investigates the feasibility of an training concept a low-resource setting.It evaluates whether educational led improved knowledge application diagnostics, cancer screening staging patient care. Material methods:The...
Abstract Objectives Despite growing interest in musculoskeletal ultrasound (MSUS), training opportunities are often limited due to staff shortages and disbalances of expertise between rural urban areas. Teledidactic approaches have the potential expand access opportunities. This study aims compare effectiveness teledidactic peer-tutored MSUS a conventional approach. Methods A course was held by student tutor following validated curriculum. An on-campus taught physician lecturers served as...
To test the prognostic role of ultrasonography at diagnosis giant cell arteritis (GCA) and change ultrasound abnormalities during initial weeks follow-up for prediction relapse, vascular complications, or initiation disease-modifying antirheumatic drugs (DMARDs). Prospective, multicentre study patients with new onset GCA undergoing serial assessment fixed time points. The Outcome Measures in Rheumatology (OMERACT) score (OGUS) was used to quantify vessel wall abnormalities. Relapse defined...
Objective Ultrasonography is crucial for diagnosing giant cell arteritis (GCA); however, training opportunities are rare. This study tested the reliability of ultrasonography findings and measurements intima-media thickness (IMT) among experts by using phantoms axillary (AA) temporal arteries (TA) created with high-resolution 3D printing. Methods Twenty-eight participants from 12 European countries received eight sets AA superficial TA (including common, frontal parietal branches), which...