A5101519577- Hematopoietic Stem Cell Transplantation
- Muscle activation and electromyography studies
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- EEG and Brain-Computer Interfaces
- Motor Control and Adaptation
- Immunotherapy and Immune Responses
- Chronic Myeloid Leukemia Treatments
- Neuroscience and Neural Engineering
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- CAR-T cell therapy research
- T-cell and B-cell Immunology
- Mesenchymal stem cell research
- Pregnancy and preeclampsia studies
- Neonatal Health and Biochemistry
- Advanced Photocatalysis Techniques
- Cytokine Signaling Pathways and Interactions
- Retinoids in leukemia and cellular processes
- Multiple Myeloma Research and Treatments
- Prosthetics and Rehabilitation Robotics
- Acute Lymphoblastic Leukemia research
- Polyomavirus and related diseases
- Immune Response and Inflammation
- Viral-associated cancers and disorders
Soochow University
2011-2024
First Affiliated Hospital of Soochow University
2011-2024
Zhejiang University
1995-2024
Worcester Polytechnic Institute
2017-2024
Wuhan University of Science and Technology
2023-2024
Rutgers Sexual and Reproductive Health and Rights
2023
Huanghuai University
2023
Second Xiangya Hospital of Central South University
2020
Central South University
2020
Zhejiang University of Technology
2019
Rift Valley fever virus (RVFV) could cause an emergency illness characterized by fever, muscle pain, and even death in humans or ruminants. However, there are no approved antiviral drugs that prevent treat RVFV infection. While therapeutic antibodies have shown promising potential for prevention treatment several studies, many studies ongoing, especially the field of infectious diseases. Among these mRNA-LNP platform shows great application, following COVID-19 pandemic. Previously, we...
Toll like receptors (TLRs) are the major agents for innate immunity that recognize invading microbial products and regulate growth of normal malignant human B lymphocytes. Multiple myeloma (MM) is a clonal plasma cell malignancy, though regulatory role TLRs in MM cells has been reported, molecular mechanism remains unclear. We first compared transcripts TLR1 to TLR10 patients healthy donors found TLR2, -4 -9 were higher bone marrow mononuclear (BMMCs) from than those donors; addition...
Recent research has advanced two degree-of-freedom (DoF), simultaneous, independent and proportional control of hand-wrist prostheses using surface electromyogram signals from remnant muscles as the input. We evaluated such regression-based controllers, along with conventional, sequential two-site co-contraction mode switching (SeqCon), in box-block, refined-clothespin door-knob tasks, on 10 able-bodied 4 limb-absent subjects. Subjects operated a commercial hand wrist socket bypass harness....
Graft-versus-host disease (GVHD), leukemia relapse, and immune deficiency remain the major limitations of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Donor natural killer cells (NK) cytokines have good potential in GVHD prevention reconstitution enhancement. Improved survival after allo-HSCT therefore requires effective prophylaxis to reduce strategy mediate graft-versus-leukemia (GVL) effect. We studied administration expanded donor NK infusion interleukin-2 (IL-2) IL-15...
Typical electromyogram (EMG) processors estimate EMG signal standard deviation (EMG σ ) via moving average root mean square (RMS) or absolute value (MAV) filters, whose outputs are used in force estimation, prosthesis/orthosis control, etc. In the inevitable presence of additive measurement noise, some subtract noise from RMS (or MAV). Others compute a difference squares (RDS)-subtract variance MAV), all followed by taking root. Herein, we model as an amplitude-modulated random process...
Single-use EMG-force models (i.e., a new model is trained each time the electrodes are donned) used in various areas, including ergonomics assessment, clinical biomechanics, and motor control research. For one degree of freedom (1-DoF) tasks, input-output (black box) common. Recently, black box have expanded to 2-DoF tasks. To facilitate efficient training, we examined parameters training methods force-varying, constant-posture tasks consisting hand open-close combined with wrist DoF. We...
System identification models relating forearm electromyogram (EMG) signals to phantom wrist radial-ulnar deviation force, pronation-supination moment and/or hand open-close force (EMG-force) are hampered by lack of supervised force/moment output in limb-absent subjects. In 12 able-bodied and 7 unilateral transradial subjects, we studied three alternative sources one degree freedom (DoF) 2-DoF target tracking tasks: (1) bilateral with feedback from the contralateral side (non-dominant for...
Abstract Flocculation performance of three kinds polyacrylamide (PAAm), linear‐PAAm, Al(OH) 3 –PAAm hybrid, and star–PAAm, in kaolin suspensions have been investigated by Spectrophotometer. It was found that the flocculation polymer flocculant is enhanced at beginning then impaired with increasing parent solution concentration ( C p ) an optimal op exists, which directly proportional to both critical concentrations * s dilute aqueous solution, can be roughly expressed empirical formula, =...
Abstract Background The fetal adrenal gland is a highly vascularized organs and develops two recognizable distinct zones in uetro, inner zone (FZ) outer definitive (DZ). Based on the region supplied, middle artery (MAA) mainly contribute to FZ while inferior (IAA) part of DZ. purpose this study was establish reference ranges Doppler indices IAA MAA, assess zonal difference blood supply gland. Methods pulsatility index (PI), resistance (RI), systolic:diastolic ratio (S/D) MAA were obtained...
To facilitate the broader use of EMG signal whitening, we studied four whitening procedures various complexities, as well roles sampling rate and noise correction. We separately analyzed force-varying constant-force contractions from 64 subjects who completed constant-posture tasks about elbow over a range forces 0% to 50% maximum voluntary contraction (MVC). From tasks, found that correction via root difference squares (RDS) method consistently reduced recording noise, often by factor 5-10....
Background Haploidentical donor hematopoietic cell transplantation (haplo-HCT) has become a preferred option for patients without HLA-matched donors, but it increases the risk of viral reactivations. Epstein–Barr virus (EBV) and cytomegalovirus (CMV) are common viruses post-HCT, limited data have been reported in setting haplo-HCT. Methods We conducted retrospective study enrolling acute leukemia who received haplo-HCT with myeloablative conditioning regimen employing ATG our center from...