- Obesity, Physical Activity, Diet
- Children's Physical and Motor Development
- Health and Lifestyle Studies
- Child Nutrition and Feeding Issues
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Obesity and Health Practices
- Adipose Tissue and Metabolism
- Physical Activity and Health
- Birth, Development, and Health
- Body Composition Measurement Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmacology and Obesity Treatment
- Child Nutrition and Water Access
- Sports Performance and Training
- Diet, Metabolism, and Disease
- Clinical Nutrition and Gastroenterology
- Urban Transport and Accessibility
- Nutrition and Health in Aging
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease Diagnosis and Treatment
- Diabetes and associated disorders
- Nutritional Studies and Diet
Louisiana State University Health Sciences Center New Orleans
2012-2023
Louisiana Cancer Research Center
2014-2019
Louisiana State University
2001-2019
Pennington Biomedical Research Center
2005-2019
Arizona State University
2018
University of New Orleans
1994-2015
University of Mississippi
2007-2015
University of Pennsylvania
2010-2014
Louisiana State University System
2010-2011
Institute on Aging
2010
Background: Increased prevalence of adolescent obesity requires effective treatment options beyond behavior therapy. Objective: To see whether sibutramine reduced weight more than placebo in obese adolescents who were receiving a therapy program. Design: 12-month, 3:1 randomized, double-blind trial conducted from July 2000 to February 2002. Setting: 33 U.S. outpatient clinics. Participants: 498 participants 12 16 years age with body mass index (BMI) that was at least 2 units the weighted...
Childhood socioeconomic status is linked to adult cardiovascular disease and risk. One proposed pathway involves inflammation due exposure a stress-inducing neighborhood environment. Whether CRP, marker of systemic inflammation, associated with stressful conditions among children unknown.The sample included 385 5-18 years age from 255 households 101 census tracts. Multilevel logistic regression analyses compared adolescents CRP levels >3 mg/L those ≤ 3 across environments. Among living in...
The National Physical Activity Plan Alliance partnered with physical activity experts to develop a report card that provides comprehensive assessment of among United States children and youth.The 2014 U.S. Report Card on for Children Youth includes 10 indicators: overall levels, sedentary behaviors, active transportation, organized sport participation, play, health-related fitness, family peers, school, community the built environment, government strategies investments. Data from nationally...
This study tested the efficacy of two school-based programs for prevention body weight/fat gain in comparison to a control group, all participants and overweight children. The Louisiana (LA) Health utilized longitudinal, cluster randomized three-arm controlled design, with 28 months follow-up. Children (N = 2,060; mean age 10.5 years, SD 1.2) from rural communities grades 4-6 participated study. Seventeen school clusters (mean 123 children/cluster) were randomly assigned one three arms: (i)...
Insulin sensitivity is impaired and ectopic fat (accretion of lipids outside typical adipose tissue depots) increased in obese adults adolescents. It unknown how early life this occurs; thus, it important to evaluate young children identify potential factors leading the development metabolic syndrome. We examined an ethnically diverse cohort healthy, exclusively prepubertal ( N = 123; F 57, M 66; age 8.04 ± 0.77 years) examine differences insulin visceral deposition between nonobese youth....
Drugs that improve chronic hyperglycemia independently of insulin signaling or reduction adiposity dietary fat intake may be highly desirable. Ad36, a human adenovirus, promotes glucose uptake in vitro proximal signaling. We tested the ability Ad36 to glycemic control vivo and determined if natural infection humans is associated with better control. C57BL/6J mice fed chow diet made diabetic high-fat (HF) were mock infected adenovirus Ad2 as for infection. Postinfection (pi), systemic...
Objectives/Goals: Increased follicle-stimulating hormone (FSH) is linked to declines in ovarian and metabolic function older women. Obesity both a manifestation driver of aging pathologies. In animal models, FSH insulin resistance (IR) were reduced after 6 mos. nutritional therapeutic (GLYLO). Our goal was translate preclinical evidence humans. Methods/Study Population: An integrated, precision medicine approach identified unique phenotype aging-related debility relative females. A...
Abstract Objective: The Wise Mind pilot study compared the efficacy of an environmental approach for prevention inappropriate weight gain in children with active control condition that used modifying expectancies related to use alcohol, tobacco, and drugs. Research Methods Procedures: A total 670 second sixth grade students from four schools were enrolled study. spanned 2 academic years, 586 available evaluation at end Two randomly assigned each treatment arm. focused on modification eating...
This study examined energy expenditure and physiologic determinants for marathon performance in recreational runners. Twenty runners participated (10 males aged 41 +/- 11.3 years, 10 females 42.7 11.7 years). Each subject completed a V(.-)O2max 1-hour treadmill run at recent pace, body composition was indirectly determined via dual X-ray absorptiometry. The male exhibited higher (ml x kg(-1) min(-1)) values (52.6 5.5) than their female counterparts (41.9 6.6), although ventilatory threshold...
Neighbourhood parks may serve as a coping resource in post‐disaster communities, yet little is known about the impact of large‐scale disasters on park use. The objective this study to explore Hurricane Katrina (August 2005) use by visitors from flooded areas New Orleans, Louisiana, compared non‐flooded areas. In 2006 and 2007, following Katrina, 201 adults who visited 27 Orleans were interviewed. Visitors neighbourhoods used their less often likely engage animal interaction than...
Objective: To investigate the hypotheses that in elementary school students: (1) adiposity and academic achievement are negatively correlated (2) physical activity positively correlated. Methods: Participants were 1963 children fourth to sixth grades. Adiposity was assessed by calculating body mass index (BMI) percentile percent fat with statewide standardized tests 4 content areas. Socioeconomic status age control variables. A subset of participants (n = 261) wore an accelerometer for 3...
To evaluate the concordance between leisure-time sedentary behavior in adolescents assessed by an activity-based questionnaire and accelerometry. A convenience sample of 128 girls 73 boys, 11-15 years age (12.6 ± 1.1 years) from six states across United States examined as part feasibility studies for Trial Activity Adolescent Girls (TAAG). Three days self-reported time spent watching TV/videos, using computers, playing video/computer games, talking on phone was a modified version...
The prevalence of childhood obesity is rapidly increasing. Successful prevention and treatment depends on increasing the physical activity patterns obese youth. However, motivating child to participate in difficult.We designed a four-phase intervention, consisting structured progressive exercise program moderate intensity, along with motivational methods increase improve body movement awareness.Seventy-three overweight children participated weight management program. They had significant...
Safe and effective exercise programs are needed to prevent treat chronic diseases in childhood. In particular, preadolescent obese children should participate activities that specific their special needs.We included a moderate intensity, progressive resistance training program multidisciplinary weight management for children. The diet, behavior modification, aerobic flexibility exercises.The subjects reported no accidents or injuries 100% compliance with the minimum required prescription....
Abstract Objective: The conventional ratio method (milliliters O 2 per mass) typically is used to express V o peak. goal of the current study was compare peak obese girls with normal‐weight by and allometric scaling methods. Research Methods Procedures: We compared methods in 46 47 girls. Indirect calorimetry measure during either treadmill running or walking. Regression analysis determine coefficients for mass stature each group ANOVA data between groups. Results: were taller had higher...
BACKGROUND. Adolescent obesity is a major public health problem. Treatment options in addition to behavioral therapy could include pharmacotherapy with sibutramine. OBJECTIVES. Concerns regarding increases blood pressure and heart rate after sibutramine treatment some adult patients precipitated the present analysis, which evaluated cardiovascular safety of plus program obese adolescents. PATIENTS AND METHODS. With this 12-month, randomized, double-blind, placebo-controlled trial 33 US...