A5002768296- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Radiation Dose and Imaging
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Brake Systems and Friction Analysis
- Prostate Cancer Treatment and Research
- Breast Cancer Treatment Studies
- Medical Imaging and Analysis
- Effects of Radiation Exposure
- Radiation Detection and Scintillator Technologies
- Spine and Intervertebral Disc Pathology
- Lung Cancer Research Studies
- MRI in cancer diagnosis
- Vascular Malformations Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pain Management and Opioid Use
- Cancer Diagnosis and Treatment
Aichi Cancer Center
2016-2025
Fujita Health University
2025
Hudson Institute
2023
Japan Clinical Cancer Research Organization
2020-2023
Liechtenstein Institute
2023
John Wiley & Sons (United States)
2023
Gunma Prefectural College of Health Sciences
2018-2020
Ibero American University
2020
Hong Kong Sanatorium and Hospital
2019
The Cancer Institute Hospital
2015
Pretreatment intensity-modulated radiotherapy quality assurance is performed using simple rectangular or cylindrical phantoms; thus, the dosimetric errors caused by complex patient-specific anatomy are absent in evaluation objects. In this study, we construct a system for generating three-dimensional (3D)-printed phantoms dosimetry. An anthropomorphic head phantom containing bone and hollow of paranasal sinus scanned computed tomography (CT). Based on surface rendering data, formed...
Abstract This study aimed to evaluate the recent trends in single-fraction conventional radiotherapy (CRT) as palliative treatment Japan, using data from National Database published by Ministry of Health, Labor, and Welfare. Data fiscal year (FY) 2014 FY2022, specifically related utilization CRT, were analyzed. Multi-fraction stereotactic body (SBRT), intensity-modulated (IMRT), brachytherapy excluded. The primary outcome was cumulative annual number CRT courses. Additionally, quarterly...
Abstract Background Accurate dosimetry is important in radiotherapy, and all equipment used for radiotherapy shoud be audited by an independent external dose audit. Radiophotoluminescence glass dosimeter (RPLD) has excellent characteristics widely postal audit; however, audit proton therapy using RPLD not been established. Purpose This study aims to develop a procedure scanning beams RPLD, estimate uncertainties, conduct multicenter pilot validate the methodology. Methods A toolkit was...
Abstract Purpose In linear accelerators, deviations in the x‐ray focal spot position significantly affect accuracy of radiation therapy. However, as bore‐type linac systems such Radixact system, cannot be assessed using conventional methods, a new evaluation method is required. This study aimed to develop novel measure and evaluate any from ideal position. Methods A structurally simplified measurement system was developed system. consisted vertically aligned metal bar an ionization chamber,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSalt linkage formation of poly(diallyldimethylammonium chloride) with acidic groups in the polyion complex between human carboxyhemoglobin and potassium poly(vinyl alcohol) sulfateEtsuo Kokufuta, Hidetoshi Shimizu, Isei NakamuraCite this: Macromolecules 1981, 14, 5, 1178–1180Publication Date (Print):September 1, 1981Publication History Published online1 May 2002Published inissue 1 September...
Abstract Background JCOG1015A1 is an ancillary research study to determine the organ-specific dose constraints in head and neck carcinoma treated with intensity-modulated radiation therapy (IMRT) using data from JCOG1015. Methods Individual patient dose-volume histograms of organs at risk (OAR) were collected 74 patients nasopharyngeal IMRT who enrolled The incidence late toxicities was evaluated cumulative method or prevalence proportion. ROC analysis used estimate optimal DVH cut-off value...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStoichiometric complexation of human serum albumin with strongly acidic and basic polyelectrolytesEtsuo Kokufuta, Hidetoshi Shimizu, Isei NakamuraCite this: Macromolecules 1982, 15, 6, 1618–1621Publication Date (Print):November 1, 1982Publication History Published online1 May 2002Published inissue 1 November 1982https://pubs.acs.org/doi/10.1021/ma00234a031https://doi.org/10.1021/ma00234a031research-articleACS PublicationsRequest reuse...
Deep inspiration breath-hold (DIBH) is widely used to reduce the cardiac dose in left-sided breast cancer radiotherapy. This study aimed develop a deep learning chest X-ray model for prediction select patients with potentially high risk of irradiation and need DIBH We 103 pairs anteroposterior lateral data (training cohort: n = 59, validation 19, test 25). All underwent breast-conserving surgery followed by radiotherapy: treatment plan consisted three-dimensional, two opposing tangential...
This retrospective study aimed to assess the efficacy and safety of palliative radiotherapy for painful non-bone lesions in patients with advanced cancer. We enrolled who underwent conventional between September 2018 2022. The treatment targets included primary tumor lesions, lymph node metastases, hematogenous other lesions. endpoint was overall pain response rate evaluable patients, determined based on International Consensus Pain Response Endpoint criteria. secondary endpoints survival,...
Abstract Purpose We aimed to evaluate the efficacy and safety of re-irradiation stereotactic body radiation therapy (SBRT) in patients with metastatic epidural spinal cord compression (MESCC) following high-dose conventional radiotherapy. Materials methods Twenty-one met eligibility criteria: an irradiation history 50 Gy 2 equivalent dose 2-Gy fractions (EQD2) or more, diagnosed MESCC cervical thoracic spines, treated SBRT 24 between April 2018 March 2023. Prior treatment was radiotherapy...
Abstract This study aimed to explore the distribution of external radiation therapy (RT) facilities, status related device installations and adoption high-precision RT using Survey Medical Institutions from Ministry Health, Labour Welfare in Japan. Analysis, categorized by hospital size prefecture, provides specific insights into trends treatment facility healthcare capabilities. Data on number devices planning systems (TPS) beds prefecture 1996 2020 were analyzed. In addition, examined...
To establish a predictive model for pain response following radiotherapy using combination of radiomic and clinical features spinal metastasis. This retrospective study enrolled patients with painful spine metastases who received palliative radiation therapy from 2018 to 2019. Pain was defined the International Consensus Criteria. The were extracted medical records pre-treatment CT images. Feature selection performed random forests ensemble learning method used build model. Area under curve...
Gold nanoparticles (AuNPs) can be used with megavolt (MV) X-rays to exert radiosensitization effects, as demonstrated in cell survival assays and mouse experiments. However, the detailed mechanisms are not clear; besides physical dose enhancement, several chemical biological processes have been proposed. Reducing AuNP concentration while achieving sufficient enhancement is necessary for clinical application of AuNPs. Here, we positively charged (+) AuNPs determine effects combined MV on DNA...
Abstract This study aims to evaluate the dosimetric accuracy of a deep learning (DL)-based deliverable volumetric arc radiation therapy (VMAT) plan generated using DL-based automated planning assistant system (AIVOT, prototype version) for patients with prostate cancer. The VMAT data (cliDose) 68 cancer treated treatment (70–74 Gy/28–37 fr) at our hospital were used (n = 55 training and n 13 testing). First, HD-U-net-based 3D dose prediction model implemented in AIVOT was customized data....
Abstract Purpose This study evaluated the trends in platform for stereotactic radiotherapy to brain (SRT), utilizing open data of National Database published by Ministry Health, Labour, and Welfare. Materials methods analyzed from FY2014 FY2021. The practices included were gamma knife surgery (GKS) SRT with a linear accelerator (LINAC). total number outpatient inpatient cases each system was annually. Results From April 2014 March 2022, 212,016 (102,691 GKS 109,325 LINAC) registered...
The purpose of this study is to examine risk factors for late rectal toxicity localized prostate cancer patients treated with helical tomotherapy (HT). patient cohort retrospective was composed 241 HT and followed up regularly. Toxicity levels were scored according the Radiation Therapy Oncology Group grading scale. clinical dosimetric potential increasing toxicity, such as age, diabetes, anticoagulants, prior abdominal surgery, prescribed dose, maximum dose rectum, percentage rectum covered...
Gold nanoparticles (AuNPs) are candidate radiosensitizers for medium-energy photon treatment, such as γ-ray radiation in high-dose-rate (HDR) brachytherapy. However, high AuNP concentrations required sufficient dose enhancement clinical applications. Here, we investigated the effect of positively (+) charged radiosensitization plasmid DNA damage induced by 192Ir γ-rays, and compared it with that negatively (-) AuNPs.We observed breaks reactive oxygen species (ROS) generation presence AuNPs...