Yu Kumazaki

ORCID: 0000-0003-1921-4546
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Medical Imaging Techniques and Applications
  • Management of metastatic bone disease
  • Lung Cancer Diagnosis and Treatment
  • Radiation Therapy and Dosimetry
  • Endometrial and Cervical Cancer Treatments
  • Breast Cancer Treatment Studies
  • Radiation Dose and Imaging
  • Lung Cancer Treatments and Mutations
  • Breast Implant and Reconstruction
  • Head and Neck Cancer Studies
  • Advances in Oncology and Radiotherapy
  • Colorectal and Anal Carcinomas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Radiation Detection and Scintillator Technologies
  • Advanced X-ray and CT Imaging
  • Effects of Radiation Exposure
  • Digital Radiography and Breast Imaging
  • Ultrasound and Hyperthermia Applications
  • Medical Imaging and Analysis
  • Breast Lesions and Carcinomas
  • Cancer Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Radiation Effects in Electronics
  • Prostate Cancer Treatment and Research

Saitama Medical University
2015-2025

Japan Clinical Cancer Research Organization
2020

Azienda Ospedaliera San Giovanni Addolorata
2017

Saitama International Medical Center
2015-2016

Saitama Red Cross Hospital
2011

Tokyo Metropolitan University
2011

Fujita Health University
2011

Kanagawa Cancer Center
2011

Kanagawa Prefectural Hospital Organization
2011

Tokyo Metropolitan Komagome Hospital
2011

Respiratory motion management (RMM) systems in external and stereotactic radiotherapies have been developed the past two decades. Japanese medical service fee regulations introduced reimbursement for RMM from April 2012. Based on thorough discussions among four academic societies concerned, these Guidelines to enable staff (radiation oncologists, radiological technologists, physicists, radiotherapy quality managers, radiation oncology nurses, others) apply therapy tumors subject respiratory...

10.1093/jrr/rrs122 article EN cc-by-nc Journal of Radiation Research 2012-12-13

10.6009/jjrt.25-0200 article EN Japanese Journal of Radiological Technology 2025-02-19

Abstract The purpose of this study was to investigate the utilization and implementation stereotactic body radiotherapy (SBRT) intensity-modulated (IMRT) in Japan up 2023. survey conducted by Japanese Society for Radiation Oncology High-Precision External Beam Radiotherapy Group Subcommittee from December 2023 February 2024. targeted patients treated with IMRT or SBRT between January 2021 2022. A comprehensive web-based questionnaire distributed 880 facilities, separate sections radiation...

10.1093/jrr/rraf009 article EN cc-by Journal of Radiation Research 2025-04-16

Purpose: Respiratory monitoring systems are used to detect the respiratory phase of patients during planning and administration gated radiotherapy by using four‐dimensional computed tomography (4DCT) or 4D positron‐emission tomography/CT (4DPET/CT) linear accelerator (linac), respectively. Generally, identical for 4DCT, 4DPET/CT, linac. However, different sometimes in combination because accessibility may differ manufacturer. The combined use phase‐based gating is concern differences timing...

10.1118/1.3512798 article EN Medical Physics 2010-11-08

We investigated the incidence and dose-volume relationships of radiation pneumonitis (RP) after concurrent chemoradiotherapy (CCRT) followed by durvalumab for locally advanced non-small-cell lung cancer (LA-NSCLC).We retrospectively analyzed records 36 patients with LA-NSCLC who underwent CCRT durvalumab. Incidence RP was correlations clinical factors parameters in radiotherapy.All received 60 Gy 30 fractions radiotherapy chemotherapy. Over a median follow-up period 7 months, grade ≥2 36%...

10.1016/j.ctro.2020.05.006 article EN cc-by-nc-nd Clinical and Translational Radiation Oncology 2020-05-30

The purpose of the study was to evaluate feasibility deformable image registration (DIR) in assessing cumulative dose distributions combination external beam radiotherapy (EBRT) and fractionated intracavitary brachytherapy (ICBT) for cervical cancer.Three-dimensional data sets five consecutive patients were used. treatment plan consisted whole pelvic EBRT (total dose: 45 Gy 25 fractions) combined with computed tomography (CT)-based high-dose rate ICBT (≥24 4 fractions high risk clinical...

10.1186/s13014-014-0293-4 article EN cc-by Radiation Oncology 2014-12-01

Definitive radiotherapy for cervical cancer consists of external-beam (EBRT) and brachytherapy. In EBRT, a central shield (CS) reduces the dose to rectum bladder. The combination whole-pelvic (WP)- CS-EBRT brachytherapy is standard protocol in Japan. Despite clinical studies, including multi-institutional trials, showing that Japanese treatment yields favorable outcomes with low rates late radiation toxicities, dose-volume parameters remain be established. We conducted retrospective analysis...

10.1093/jrr/rrz023 article EN cc-by Journal of Radiation Research 2019-04-15

Durvalumab after concurrent chemoradiotherapy (CCRT) for locally advanced non-small cell lung cancer (LA-NSCLC) has been found to significantly improve overall survival (OS). However, the effect of durvalumab on local control remains unclear. Here, we evaluated in comparison with clinical result patients treated CCRT alone.A total 120 LA-NSCLC including 76 alone and 44 followed by were analyzed. Baseline patient characteristics cohort compared student's t test or Mann-Whitney U continuous...

10.1111/1759-7714.13764 article EN cc-by-nc-nd Thoracic Cancer 2020-12-01

The Task Group 218 (TG-218) report was published by the American Association of Physicists in Medicine 2018, recommending appropriate use gamma index analysis for patient-specific quality assurance (PSQA). paper demonstrates that PSQA radiotherapy Japan appropriately applies considering TG-218.This survey estimated acceptance state radiotherapeutic institutes or facilities guideline using a web-based questionnaire. To investigate an facility-specific conditions, we researched optimal...

10.1002/acm2.13745 article EN Journal of Applied Clinical Medical Physics 2022-08-26

Abstract The first magnetic resonance (MR)-guided radiotherapy system in Japan was installed May 2017. Implementation of online MR-guided adaptive (MRgART) began February 2018. Online MRgART offers greater treatment accuracy owing to the high soft-tissue contrast MR-images (MRI), compared that X-ray imaging. Japanese Society for Magnetic Resonance Medicine (JSMRM), Medical Physics (JSMP), Radiological (JRS), Technology (JSRT), and Radiation Oncology (JASTRO) jointly established comprehensive...

10.1093/jrr/rrac048 article EN Journal of Radiation Research 2022-08-10

ObjectiveThe purpose of this study was to clarify operational situations, treatment planning and processes, quality assurance control with relevance stereotactic radiotherapy, intensity-modulated radiotherapy image-guided in Japan.

10.1093/jjco/hyu041 article EN Japanese Journal of Clinical Oncology 2014-04-11

The aim of this study is to analyze the incidence and risk factors for pneumonitis when immune checkpoint inhibitors (ICIs) are combined with palliative thoracic radiotherapy (RT) lung cancer. We retrospectively evaluated 29 patients cancer who received ICIs after RT (30 Gy in 10 fractions). Their were pembrolizumab (n = 17), nivolumab 8) atezolizumab 4). Median follow-up period was months. median interval between starting ICI 25 days. Pneumonitis events grade 1 10; 34%), 2 4; 14%) 3 3;...

10.1093/jrr/rrab051 article EN cc-by-nc Journal of Radiation Research 2021-05-27

Abstract Background Intensity‐modulated radiotherapy (IMRT) has been increasingly used for patients with locally advanced non‐small cell lung cancer (LA‐NSCLC). However, there are some barriers to implementing IMRT LA‐NSCLC, including the complexity of treatment plan optimization. This study aimed evaluate learning curve dose optimization in LA‐NSCLC and identify factors that affect degree achievement Methods We retrospectively evaluated 40 consecutive who received concurrent...

10.1111/1759-7714.15046 article EN cc-by-nc-nd Thoracic Cancer 2023-07-19

Treatment outcomes after salvage re-irradiation in patients with recurrent head and neck cancer vary widely due to heterogeneous patient characteristics, it is difficult evaluate optimal schedules. This study aimed validate a nomogram, originally developed by Tanvetyanon et al., used predict the survival probability of re-irradiation. Twenty-eight who underwent between June 2007 November 2011 were evaluated. The median total dose for initial radiotherapy was 60 Gy (range, 22–72)....

10.1093/jjco/hys210 article EN Japanese Journal of Clinical Oncology 2012-12-12

This study evaluated the feasibility of applying volumetric-arc radiotherapy (VMAT) in standard curative for non-bulky cervical cancer using central-shielding principle. Whole-pelvis irradiation 20 Gy and pelvis 30 Gy, both 2 fractions, were created 3D conformal (3DCRT) with a midline block or VMAT. Composite dose distributions DVH parameters compared first simple phantom model then 10 clinical cases Stage I-II cancer. target volumes (CTVs) from published guidelines primary disease lymph...

10.1093/jrr/rry054 article EN cc-by Journal of Radiation Research 2018-06-21

In Japan, breast-conserving surgery with closed cavity has generally been performed for breast cancer patients, and accelerated partial irradiation (APBI) is considered difficult because Asian females have smaller sizes than Western females. Therefore, common identification of target treatment plan method in APBI required. A prospective multicenter study was conducted Japan to determine institutional compliance using high-dose-rate interstitial brachytherapy (ISBT) designed Japanese female...

10.1186/s13014-015-0430-8 article EN cc-by Radiation Oncology 2015-06-04

Background/Aim: A retrospective study was conducted to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) for pulmonary oligometastasis from colorectal cancer (CRC). Patients Methods: with CRC who were treated SBRT between April 2010 October 2018 enrolled in this study. All patients underwent using Cyberknife® a dose 54-60 Gy 3 fractions 99% clinical target volume. The treatment evaluated by local control (LC) overall survival (OS) rates. toxicity National Cancer...

10.21873/invivo.12130 article EN In Vivo 2020-01-01

Abstract The Japan Clinical Oncology Group–Radiation Therapy Study Group (JCOG-RTSG) has initiated several multicenter clinical trials for high-precision radiotherapy, which are presently ongoing. When conducting multi-center trials, a large difference in physical quantities, such as the absolute doses to target and organ at risk, well irradiation localization accuracy, affects treatment outcome. Therefore, differences various quantities used different institutions must be within an...

10.1093/jrr/rraa089 article EN cc-by Journal of Radiation Research 2020-09-04
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