A5065935505- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Head and Neck Cancer Studies
- Radiation Therapy and Dosimetry
- Esophageal Cancer Research and Treatment
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Lymphoma Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Endometrial and Cervical Cancer Treatments
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- Lung Cancer Treatments and Mutations
- DNA Repair Mechanisms
- Management of metastatic bone disease
- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Metastasis and carcinoma case studies
- Hepatocellular Carcinoma Treatment and Prognosis
Keio University
2015-2024
University of Tsukuba
2021-2023
Keio University Hospital
2004-2021
Japan Radioisotope Association
2014
Indiana University School of Medicine
2013
Chiba University
1998-2006
Kyoto University
1998
Argonne National Laboratory
1992-1995
University of Chicago
1992-1994
UCSI University
1992
ABSTRACT This study aimed to examine the efficacy of semantic segmentation implemented by deep learning and confirm whether this method is more effective than a commercially dominant auto-segmentation tool with regards delineating normal lung excluding trachea main bronchi. A total 232 non-small-cell cancer cases were examined. The computed tomography (CT) images these converted from Digital Imaging Communications in Medicine (DICOM) Radiation Therapy (RT) formats arrays 32 × 128 voxels...
The ability of the potential chemopreventive agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) to protect against radiation-induced mutagenesis at hprt locus and cell killing was studied using CHO-AA8 cells incubated for 30 min 37°C in growth medium containing its active thiol 2-[(aminopropyl)amino]ethanethiol (WR-1065). In parallel experiments, disulfide forms drug present incubation were determined order identify which, if either, components associated with observed...
Radiation Injury After Hypofractionated Stereotactic Radiotherapy for Peripheral Small Lung Tumors: Serial Changes on CTToshiaki Takeda1, Atsuya Etsuo Kunieda1 2, Akitoshi Ishizaka3, Kazuhiko Takemasa1, Kyoko Shimada1, Seika Yamamoto1, Naoyuki Shigematsu2, Osamu Kawaguchi2, Jun-ichi Fukada1 Toshio Ohashi2, Sachio Kuribayashi2 and Atsushi Kubo2Audio Available | Share
Aim: To investigate the efficacy and toxicity of hypofractionated stereotactic radiotherapy for treatment patients presenting with hepatocellular carcinoma (HCC) in a single institutional setting. Methods: Sixteen who presented solitary HCC, including two tumor thrombus portal veins, were treated or without transarterial chemoembolization. The criteria existence technical difficulties other ablation therapies, inoperable disease refusal to undergo surgery, staged as Grade A B according...
The aim of this study was to investigate significant clinical, tumour-related and dosimetric factors among patients with grade 0-1, 2 3 radiation pneumonitis (RP) after stereotactic body radiotherapy (SBRT) for lung tumours.Patients (n=128) a total 133 tumours treated SBRT 50 Gy in 5 fractions were analysed. RP graded according the Common Terminology Criteria Adverse Events v.3.0. Significant identified by univariate multivariate analyses. Threshold dose-volume histograms (DVHs) constructed...
Under hypoxic conditions, nitroimidazoles can replace oxygen as electron acceptors, thereby enhancing the effects of radiation on malignant cells. These compounds also accumulate in cells, where they act cytotoxins or imaging agents. However, whether these apply to cancer stem cells has not been sufficiently explored. Here we show that 2-nitroimidazole doranidazole potentiates radiation-induced DNA damage glioma (GSCs) and confers a significant survival benefit mice harboring GSC-derived...
This study aimed to assess the imaging appearances of focal liver reactions following stereotactic body radiotherapy (SBRT) for small hepatocellular carcinoma (HCC) and examine relationships between appearance baseline function. We retrospectively studied 50 lesions in 47 patients treated with SBRT (30-40 Gy 5 fractions) HCC, who were followed up more than 6 months. After SBRT, all underwent regular follow-ups blood tests dynamic CT scans. At a median follow-up 18.1 months (range 6.2-43.7...
In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors.Possible factors for local control TNM stage and type surgical procedures: T2 or 1'3 tumors use total maxillectomy showed better rates (P < 0.01).High radiation doses 40 Gy more also seemed be significance: P 0.2 60 Gy, 0.1 more.The risk cervical relapse increased when cheek alveolus was grossly involved 0.2).However, since...
The aim was to determine the incidence of seed migration not only chest, but also abdomen and pelvis after transperineal interstitial prostate brachytherapy with loose (125)I seeds.We reviewed records 267 patients who underwent seeds. After implantation, orthogonal chest radiographs, an abdominal radiograph, a pelvic radiograph were undertaken routinely document occurrence sites migration. abdomen, calculated. All had subsequently computed tomography scan identify exact location migrated...