A5008461685- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Inflammatory Biomarkers in Disease Prognosis
- Tracheal and airway disorders
- Cancer Cells and Metastasis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Minimally Invasive Surgical Techniques
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
- Multiple and Secondary Primary Cancers
- Hernia repair and management
- Cancer, Lipids, and Metabolism
- Peptidase Inhibition and Analysis
- Protease and Inhibitor Mechanisms
- Head and Neck Cancer Studies
- Soft Robotics and Applications
- Lung Cancer Treatments and Mutations
The Japanese Society of Gastroenterological Surgery
2021-2024
Kobe University
2024
Keio University Shonan Fujisawa
2023
San-ikukai Hospital
2023
Keio University
2013-2022
Keio University Hospital
2006-2021
Secretaria de Planejamento e Gestão
2018
Shibaura Institute of Technology
2018
Saitama Medical University
2016
Creative Research Enterprises (United States)
2016
The aim of this study was to assess the impact postoperative complications after esophagectomy on long-term outcome. treatment esophageal cancer has recently been improved; however, with thoracotomy and laparotomy carries considerable morbidity mortality. real overall survival is still under evaluation. A retrospective analysis performed patients who underwent laparotomy, R0 or R1 resection between January 1997 December 2012. Of 402 patients, we analyzed following parameters 284 could be...
In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedures have been standardized, and safety efficacy of surgery evaluated. accordance with social acceptance as less invasive type number has increased all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. Notably, technical skills certification system surgeons established by JSES to train instructors on how teach...
Abstract This article reports the results of 16th National Survey conducted by Japan Society for Endoscopic Surgery (JSES) 2020 and 2021. Laparoscopic cholecystectomy was first introduced to in 1990 has rapidly become popular because its minimally invasive nature. Since then, number objective organs indications laparoscopic surgery have gradually expanded. In 2021, 290 787 patients underwent endoscopic all surgical domains. Of these, 124 614, 110 757, 23 156, 21 771, 6543, 2614, 535, 465,...
The number of dissected lymph nodes (LNs), surgical outcomes, and postoperative recurrence-free survival (RFS) were compared between thoracic duct (TD)-preserved TD-resected groups. distribution metastasis in LNs around TD (TDLN) was reviewed. Transthoracic esophagectomy (TTE) with resection for esophageal cancer patients has been one the standard procedures. Because adipose tissue surrounding contains LNs, might be necessary radical LN dissection. However, few studies have investigated...
Abstract In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedure has been standardized, and safety usefulness of surgery have evaluated. accordance with social acceptance as less‐invasive number procedures increasing all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. For example, JSES established technical skills certification system surgeons to train...
Among multidisciplinary therapies developed for advanced esophageal cancer, neoadjuvant chemotherapy and chemoradiotherapy have been established as standard treatments. To deliver cautious follow up intense treatment high-risk patients, a simple instructive biomarker the postoperative recurrence needs to be identified. Fibrinogen, common component of hemostasis, has suggested not only play an important role in cancer metastasis, but also correlate with tumor recurrence. We aim clarify...
Abstract Background CC-chemokine receptor 7 (CCR7), a known lymph node homing for immune cells, has been reported as key molecule in metastasis. We hypothesized clinicopathological correlation and functional causality between CCR7 expression metastasis patients with esophageal squamous cell carcinoma (ESCC). Methods performed immunohistochemical analysis of 105 consecutive 61 exclusive pathological T1 ESCC patients, followed by adhesion assay vivo experiment using newly developed mouse...
The flavonoid nobiletin (5,6,7,8,3',4'-hexamethoxyflavone), found in Citrus depressa Rutaceae, a popular citrus fruit Okinawa, Japan, reportedly inhibits the production of pro-matrix metalloproteinase (proMMP)-1, 3, and 9 rabbit synovial fibroblasts vitro. In present study, we demonstrated inhibitory effects on proliferation cancer cell line, TMK- 1, its MMPs. SCID mouse model, that inhibited formation peritoneal dissemination nodules from TMK-1. enzymatic activity MMP-9 expressed culture...
Sivelestat sodium hydrate is a selective inhibitor of neutrophil elastase, which effective in acute lung injury associated with systemic inflammatory response syndrome. However, the effectiveness sivelestat sepsis has not been fully examined. In present study, effect on severe rat cecal ligation and puncture (CLP) model was investigated. Adult male Sprague-Dawley rats underwent CLP were randomly divided into two groups: sivelestat-treated group saline-treated controls. The serum...
Xanthogranulomas are known to develop in the gallbladder and kidney. Xanthogranuloma of stomach is a rare disease, best our knowledge, only few cases have been reported date. The present patient was 64‑year‑old man who underwent wide resection following Billroth‑I reconstruction for gastric ulcer ~40 years prior current presentation. Due tarry stools, gastrointestinal endoscopy performed, leading identification an ulcerated lesion located at previous suture line lesser curvature remnant...
Abstract Background Oesophageal squamous cell carcinoma is an aggressive disease owing to early and widespread lymph node metastases. Multimodal therapy radical surgery may improve prognosis. Few studies have investigated the efficacy of thoracic duct resection. Methods Patients with oesophageal who underwent transthoracic minimally invasive oesophagectomy (TMIE) for cancer at Keio University Hospital between January 2004 December 2016 were selected. Between 2008, TMIE was performed in...