A5032856038- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver physiology and pathology
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Hepatitis C virus research
- Organ Donation and Transplantation
- Esophageal and GI Pathology
- Renal Transplantation Outcomes and Treatments
- Colorectal Cancer Treatments and Studies
- Tissue Engineering and Regenerative Medicine
- Gallbladder and Bile Duct Disorders
- Pancreatic function and diabetes
- Pancreatitis Pathology and Treatment
- Hepatitis B Virus Studies
- Colorectal Cancer Surgical Treatments
- Clinical Nutrition and Gastroenterology
- Pediatric Hepatobiliary Diseases and Treatments
- Transplantation: Methods and Outcomes
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Metastasis and carcinoma case studies
Nagasaki University
2016-2025
The Japanese Society of Gastroenterological Surgery
2019-2024
Nagasaki University Hospital
2013-2024
Samsung Medical Center
2023
Washington Center for Weight Management and Research
2023
Standard Bio (Norway)
2023
Yahoo (United Kingdom)
2023
Hirosaki University
2023
Osaka University
2023
Sungkyunkwan University
2023
When right hemi-hepatectomy without middle hepatic vein (MHV) is performed in a living donor (LD), MHV tributaries such as V5 and V8 may be preserved during parenchymal transection to preserve liver function reduce the damage of graft. However, no study has so far investigated whether this preservation impact on live operation or graft function.Of 52 hepatectomies for lobe LD, were 11 cases, while, remaining 41 cases sacrificed when those encountered transection.There was significant...
The purpose of this study was to develop a bioartificial liver (BAL) treat patients with severe failure until they can be either transplanted or recover spontaneously.Severe acute is associated high mortality. Liver transplantation has emerged as an effective therapy for who did not respond standard management. However, because the donor organ shortage and urgent need transplantation, many die before others do survive after primarily intracranial hypertension.Three groups were treated BAL....
The Japanese National Clinical Database (NCD) is a large-scale, nationwide, web-based data entry system that linked to the surgical board certification and covers almost all cases carried out in Japan.To evaluate outcomes according gastroenterological section of NCD.The 115 procedures stipulated by "Training Curriculum for Board-Certified Surgeons Gastroenterology" were registered from 2011 2017. number surgeries, preoperative comorbidities, short-term compared between registration...
As of 31 December 2017, a total 9242 liver transplants have been carried out in 67 institutions Japan. There were 447 deceased donor (444 from heart‐beating donors and 3 non‐heart‐beating donors) 8795 living‐donor transplants. The annual 2017 was 416 (69 347 transplants). most frequent indication cholestatic disease, followed by neoplastic disease hepatocellular disease. In terms cirrhosis due to hepatitis C B decreased (13 8, respectively), whereas alcoholic markedly increased (32). Patient...
Abstract Background We aimed to present the 2019 annual report of gastroenterological section National Clinical Database (NCD). Methods reviewed 609,589 cases recorded in and 5,029,764 registered from 2011 for 115 selected surgical procedures. Results The main features surgery Japan were similar those described 2018 report, namely, that 1) operative numbers gradually increased all procedures, except gastrectomy hepatectomy, which decreased these years; 2) eight major surgeries, age...
Atezolizumab plus bevacizumab therapy is extremely effective in the treatment of intermediate-stage hepatocellular carcinoma (HCC), with a response rate 44%, as reported IMbrave150 trial. When tumor shrinkage obtained, achieving complete (CR) possible many cases using curative conversion resection, ablation, or superselective transarterial chemoembolization (TACE) intent. This concept, i.e., by combining systemic and locoregional therapy, has not been before. multicenter proof-of-concept...
The National Clinical Database (NCD) of Japan is a nationwide data entry system for surgery, and it marked its 10th anniversary in 2020. aim was to present the 2020 annual report gastroenterological surgery NCD.
In Japan, the first endoscopic surgery, a laparoscopic cholecystectomy, was performed in 1990. Since then, operative procedures have been standardized, and safety efficacy of surgery evaluated. accordance with social acceptance as less invasive type number has increased all surgical domains. The Japan Society for Endoscopic Surgery (JSES) played an important role development Japan. Notably, technical skills certification system surgeons established by JSES to train instructors on how teach...
Abstract The National Clinical Database (NCD) of Japan grew rapidly, harvesting over 11 million cases data between 2011 and 2018 from more than 5000 facilities. This is the Report NCD based upon gastrointestinal surgery information in 4 420 175 to 2018. More 70% all surgeries were performed at certified institutions, percentage institutions was particularly high for esophagus (93.8% 2018), liver (89.4%), pancreas (91.3%), spleen (86.9%). Also, with participation board‐certified surgeon. As...
Recent advances in systemic therapy for hepatocellular carcinoma (HCC) have led to debates about the feasibility of combination therapies, such as combined with surgery or transarterial chemoembolization, patients advanced HCC. However, a lack consensus on oncological resectability criteria has hindered discussions "conversion therapy" and optimal management To address this issue, Japan Liver Cancer Association (JLCA) Japanese Society Hepato-Biliary-Pancreatic Surgery (JSHBPS) established...
Abstract Background High recurrence rates after liver resection with curative intent for hepatocellular carcinoma (HCC) remain a problem. The characterization of long-term survivors without may help improve the therapeutic strategy HCC. Methods A nationwide Japanese database was used to analyse 20 811 patients HCC who underwent intent. Results 10-year recurrence-free survival rate 22·4 per cent. Some 281 were more than 10 years. HCCs measured less 5 cm in 83·2 cent, single lesion present...
Abstract Endoscopic submucosal dissection (ESD) permits en bloc removal of superficial oesophageal squamous cell carcinoma (ESCC). However, post-procedure stricture is common after ESD for widespread tumours, and multiple endoscopic balloon dilation (EBD) procedures are required. We aimed to evaluate the safety effectiveness transplantation tissue-engineered autologous oral mucosal epithelial sheets that had been transported by air over a distance 1200 km in controlling postprocedural...
The aim of the present study was to evaluate value anatomical resection for hepatocellular carcinoma (HCC) with microportal vascular invasion (vp1) between 2000 and 2010.Vascular has been reported as a prognostic factor liver HCC. Anatomical HCC resulted in optimum outcomes eradicating intrahepatic micrometastases through portal vein, but opposite results have also reported.A clinical chart review performed 546 patients vp1. We retrospectively evaluated recurrence-free survival (RFS) (AR)...
As of December 31, 2014, 7937 liver transplants (7673 living donor and 264 deceased transplantations [DDLTs; 261 from heart-beating donors 3 non-heart-beating donors]) have been performed in 67 institutions Japan. The revised Organ Transplant Law Japan came into effect July 2010, which allows organ procurement brain-dead individuals, including children, with family consent if the patient had not previously refused donation. However, number donations has increased as anticipated. rate per...
Atezolizumab plus bevacizumab therapy has high response rates in patients with unresectable hepatocellular carcinoma (HCC). The hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) been reported to be useful as an biomarker for detecting β-catenin mutations. We evaluated whether the pretreatment EOB-MRI could predict therapeutic effect lenvatinib and atezolizumab bevacizumab.This study included 68 (lenvatinib group (n = 33) 35)). visual assessment relative...
PURPOSE Durable partial response (PR) and durable stable disease (SD) are often seen in patients with hepatocellular carcinoma (HCC) receiving atezolizumab plus bevacizumab (atezo-bev). This study investigates the outcome of these histopathology residual tumors. PATIENTS AND METHODS The IMbrave150 study's atezo-bev group was analyzed. PR or SD per RECIST v1.1 lasting more than 6 months defined as durable. For histologic analysis, a comparable real-world from Japan Taiwan who had undergone...
A reproducible experimental animal model of fulminant hepatic failure (FHF) resembling the clinical condition is needed. We have developed such a in rat by combining resection two anterior liver lobes (68% mass) with ligation right pedicle (24% mass), resulting necrosis; remaining omental (8% are left intact. Adult Sprague-Dawley rats (250-300 g) were used. Survival time was determined 60 rats. Because maintenance body temperature at 37 degrees C shortened survival half, FHF not warmed...