Behavioral plasticity is the most striking trait in locust phase transition. However, genetic basis for behavioral locusts largely unknown. To unravel molecular mechanisms underlying change migratory Locusta migratoria, gene expression patterns over time courses of solitarization and gregarization were compared by oligonucleotide microarray analysis. Data analysis revealed that several categories relevant to peripheral olfactory perception are strongly regulated a total 1,444 differentially...

A second COVID-19 vaccine booster dose is effective and safe for older adults. This study investigated hesitancy to take up a its determinants among adults in Hong Kong. Participants were Chinese-speaking community-dwelling aged 65 years or above. Telephone numbers randomly selected from up-to-date telephone directories. total of 370 participants completed the survey. Logistic regression models fitted data analysis. Among participants, half (52.4%) hesitant receive dose. After adjustment...

Herpes zoster (HZ) among older adults has consistently been a concern. Despite the availability of vaccines, HZ vaccination remains underutilized globally. This study investigated behavioral intention in Hong Kong to receive self-financed or fully subsidized vaccines. A random telephone survey was conducted between July and October 2023, involving 673 community-dwelling individuals aged 65 years older. Among 636 unvaccinated participants, 7.7% intended two doses vaccine if self-financed,...

Mothers play a crucial role in influencing their daughters' HPV vaccination decisions. Addressing barriers to receiving among mothers of girls may achieve two goals one strike: increasing coverage both and daughters. This study aims examine the uptake its determinants China at individual interpersonal levels. From July October 2023, cross-sectional online was conducted investigate vaccine refusal for daughters aged 9–17 years 11,678 Shenzhen, China. A randomized selection method employed,...

Oxidative stress is one of the main contributors in pathogenesis diabetic retinopathy. The aim this study to investigate effects SS31 which a mitochondria-targeted antioxidant peptide on retinas streptozotocin (STZ)-induced rats. Two weeks after induction diabetes, (3 mg/kg) or same volume normal saline (N.S) was injected subcutaneously into back rats every day. Four months later, integrity inner blood retinal barrier (iBRB) measured by Evans blue perfusion. expression and distribution...

Hemophagocytic lymphohistiocytosis (HLH) is an immune-mediated syndrome resulting in cytokine storm. The uncontrolled storm leads to significant tissue damage and potentially life-threatening multiorgan failure. Conventional first-line treatment for HLH included HLH-94 protocol or HLH-2004 protocol. However, up 30% of patients do not respond therapy. We reported 3 cases secondary HLH/macrophage activation which were caused by lymphoma (2 cases) adult-onset still's disease. They received low...

China started to offer human papillomavirus (HPV) vaccines females aged 9-45 years in 2016. However, there was a lack of reports about HPV vaccination coverage representative sample China. Therefore, this study aimed examine the current and associated factors among 9-50 Shenzhen, China, based on administrative health records kept by community centers. A multistage random sampling approach used. The research team randomly selected 18 centers 3118 were then from these Among all participants,...

This study investigated the influences of mother-daughter communication and social media on mothers' HPV vaccine refusal for their daughters aged 9-17. A cross-sectional online survey among 11,728 mothers girls 9-17 in Shenzhen, China was implemented between July October 2023. Multi-level logistic regression models were fitted. Among participants, 43.2% refused to have receive an vaccination. In multivariate analysis, more openness (AOR: 0.99, 95%CI: 0.98, 0.99), perceived positive outcomes...

Vaccination against COVID-19 remains one of the ultimate solutions to ongoing pandemic. This study examined and compared completion primary vaccination series associated factors in slum estate communities Uganda. was a cross-sectional survey conducted among 1025 residents. Logistic regression models were fitted. Of participants, 511 residents 514 Completion 43.8% community 39.9% (p = 0.03). Having more knowledge about positively with completing both communities. Perceived benefits cues...

During the Coronavirus Disease 2019 (COVID-19) pandemic, seasonal influenza remained a significant health threat for older adults. Seasonal vaccination (SIV) is highly effective and safe This study investigated associations of COVID-19 vaccination, perceptions related to SIV, with behavioural intention receive SIV among adults in Hong Kong, China. A random telephone survey was conducted 440 community-dwelling Kong residents aged 65 years or above, between November 2021 January 2022. Among...

China is considering to offer COVID-19 vaccination for children aged 6–35 months. This study investigated the changes in vaccine acceptability and associated factors among parents with months 2020 2021. Two rounds of cross-sectional online surveys were conducted adult factory workers Shenzhen, China. A subset 208 (first round) 229 (second at least one child was included study. Parental increased significantly from 66.8% first round 79.5% second (p = 0.01). Positive attitudes, perceived...

China started to implement the HPV vaccination program for females in 2016. This study investigated associations between mothers' decisional conflicts, satisfaction with governmental health promotion materials, and their daughters' uptake.

Multiple myeloma (MM) is a hematological malignancy that lacks cure. However, novel combination therapy current anti-MM strategy. Doxorubicin (DOX) type of anthracycline which first-line chemotherapeutic for treating MM and induces senescence in many types cancer. Dinaciclib potent, small molecule CDK inhibitor with promise several cancer I/II phase clinical trials. In the present study anticancer effects underlying mechanisms dinaciclib combined DOX RPMI-8226 cells were investigated....

Compliance with personal preventive measures (PPMs) remains essential in the prevention and control of coronavirus disease 2019 (COVID-19) pandemic future infectious outbreaks. This study aimed at examining comparing practice COVID-19 PPMs associated factors selected slum estate communities Uganda.

PAX5 encodes a transcription factor essential for B-cell differentiation, and haploinsufficiency is involved in tumorigenesis. There were few studies on how regulated genes expression to promote In this study, we constructed the cell model of using gene editing technology Raji cells, detected differentially expressed used protein-protein interaction networks cluster analysis comprehensively investigate cellular pathways haploinsufficiency. The clusters transcription, inflammatory immune...

Laohugou glacier No. 12 (LHG12), located in the northeast of Qinghai–Tibet Plateau, is largest valley Qilian mountains. Since 1957, LHG12 has shrunk significantly. Due to limitations situ observations, simulations and investigations have higher levels uncertainty. In this study, consumer-level, low-altitude microdrones were used conduct repeated photogrammetry at lower part LHG12, a digital orthophoto map (DOM) surface model (DSM) with resolution centimeter scale generated, from 2017 2021....

In this study, we are going to investigate the effect of nano carbon combined with ex vitro anatomical sorting on detection rate lymph nodes (LNs) in gastric cancer (GC) along analysis correlation between LNs and patients’ prognosis. The clinical data patients undergoing radical gastrectomy Shanxi Bethune Hospital, Academy Medical Sciences, Tongji Third Hospital University from January 2018 2019 were examined retrospectively. According whether they adopt tracing specimen method, divided into...

The role of SMU1 in DNA replication and RNA splicing is well-established, yet its specific function dysregulated mechanisms gastric cancer (GC) remain inadequately elucidated. This study seeks to investigate the potential oncogenic progression-promoting effects GC, with ultimate goal informing novel approaches for treatment diagnosis.

Objective: This paper aims to evaluate the effect of laparoscopic complete mesocolic resection on efficacy and survival patients with colon cancer. Methods: 80 cancer were included in this study, 40 whom treated traditional radical surgery as control group, other observation group. The study period lasted from April 2022 2023, surgical indexes, postoperative recovery, quality life, occurrence complications two groups monitored throughout whole process compared analyzed. Results: therapeutic...

To infer the network protocol state machine is very useful in security-related contexts, both research and management. This process follows an extension of classic Angluins L* algorithm has achieved extended version some Mealy automata to represent or model a communication protocol. The been validated by inferring from SMTPFTP protocol, tested offline algorithms for comparison experiments. experimental results show that this method can more accurately identify important application value.

INTRODUCTION:Haemophagocytic syndrome is a life-threatening clinical syndrome, which can lead to tissue damage and progressive systemic organ failure.But there was no report on hypopituitarism induced by haemophagocytic syndrome. PURPOSE:Here we reported one case of after treatment associated with Epstein-Barr virus -positive aggressive natural killer cell leukemia.After control, the patient felt too weak, tired dizzy sit up, he also had symptom depression, loss appetite, polyuria...