A5101669143- Tissue Engineering and Regenerative Medicine
- Pluripotent Stem Cells Research
- EEG and Brain-Computer Interfaces
- Reproductive Biology and Fertility
- Genital Health and Disease
- Cervical Cancer and HPV Research
- Neuroscience and Neural Engineering
- Congenital heart defects research
- Congenital Heart Disease Studies
- Plant nutrient uptake and metabolism
- Hepatitis B Virus Studies
- Animal Genetics and Reproduction
- Transcranial Magnetic Stimulation Studies
- Renal and Vascular Pathologies
- Advanced Glycation End Products research
- Cellular Mechanics and Interactions
- Functional Brain Connectivity Studies
- Amyotrophic Lateral Sclerosis Research
- Plant responses to water stress
- Molecular Biology Techniques and Applications
- CRISPR and Genetic Engineering
- Skin and Cellular Biology Research
- S100 Proteins and Annexins
- Chronic Kidney Disease and Diabetes
- Medical Research and Treatments
Sichuan University
2024-2025
West China Hospital of Sichuan University
2024-2025
Guiyang Medical University
2024
Affiliated Hospital of Guizhou Medical University
2024
China Agricultural University
2024
Shenzhen Bay Laboratory
2023-2024
Lanzhou University
2024
First Hospital of Lanzhou University
2024
Xiamen University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
To assess the pattern of multiple human papillomavirus infection to predict type replacement postvaccination. A total 7372 women aged 18–45y from a phase III trial an Escherichia coli-produced HPV-16/18 vaccine were analyzed at enrollment visit before vaccination. Hierarchical multilevel logistic regression was used evaluate HPV and nonvaccine-type interactions with age as covariate. Binary construed compare infections single explore impact multiple-type on risk cervical disease. Multiple...
The dilemma of achieving 'onco-functional balance' in gliomas affecting the motor cortex highlights importance functionally-guided resection strategies. While accurate mapping eloquent areas often requires frequent electrical stimulation, this practice can lead to side effects like seizures and postoperative deficits. To enhance safety functional mapping, we studied how impact hand movement assessed effectiveness cortical activity for setting. We recruited patients with individuals an...
Abstract Cardiovascular diseases have emerged as one of the leading causes human mortality, but discovery new drugs has been hindered by absence suitable in vitro platforms. In recent decades, continuously refined protocols for differentiating induced pluripotent stem cells (hiPSCs) into hiPSC‐derived cardiomyocytes (hiPSC‐CMs) significantly advanced disease modeling and drug screening; however, this led to an increasing need monitor function hiPSC‐CMs. The precise regulation action...
Current diagnostic methods for diabetic nephropathy (DN) lack precision, especially in early stages and monitoring progression. This study aims to find potential biomarkers DN progression evaluate their accuracy. Using serum samples from healthy controls (NC), patients (DM), early-medium stage (DN-EM), late-stage (DN-L), researchers employed quantitative proteomics Mfuzz clustering analysis revealed 15 proteins showing increased expression during progression, hinting at biomarker potential....
The subcortical maternal complex, which consists of maternal-effect genes, plays a crucial role in the development oocytes and preimplantation embryo until activation zygote genome. One such gene, known as peptidyl-arginine deiminase VI (Padi6), is involved oocyte maturation, fertilization embryonic development. However, precise function Padi6 gene buffalo still unclear requires further investigation. In this study, sequence, mRNA protein expression patterns were analyzed oocytes, embryos...
The severity of flood disasters is increasing due to climate change, resulting in a significant reduction the yield and quality forage crops worldwide. This poses serious threat development agriculture livestock.
Glioma cells can reshape functional neuronal networks by hijacking synapses, leading to partial or complete neurological dysfunction. These mechanisms have been previously explored for language functions. However, the impact of glioma on sensorimotor functions is still unknown. Therefore, we recruited a control group patients with unaffected motor cortex and glioma-infiltrated cortex, recorded high-density electrocortical signals during finger movement tasks. The results showed that...
Summary Understanding the mechanisms of blastocyst formation and implantation is crucial for advancing farm animal reproduction. However, research in this area often hindered by limited availability embryos. In study, we developed an efficient method to generate blastocyst-like structures (termed blastoids) from porcine expanded pluripotent stem cells (pEPSCs) through chemical induction with efficiency up 80%. These blastoids closely resemble natural blastocysts terms morphology, cell...
Involvement of the visual pathway in amyotrophic lateral sclerosis (ALS) has been demonstrated. However, exact damage mechanisms such as how changes distinct parts anterior (AVP) are still poorly understood and remain highly controversial. We observed altered RNFL, fractional anisotropy, mean diffusivity relative anisotropy AVP by multimodal use optical coherence tomography DTI ALS individuals compared to controls. Our findings shed light on dynamic pathophysiological effects morphology...
ABSTRACT High‐risk human papillomavirus (HR‐HPV) testing, utilizing both DNA and RNA methods, offers enhanced sensitivity compared to cytology for detecting high‐grade cervical intraepithelial neoplasia (CIN2+). Meanwhile, HR‐HPV E6 E7 mRNAs are more likely differentiate the transient infection from persistent than DNA. Aptima HPV can not only detect mRNA but also though it is much efficient at Currently, there few studies on distribution of in same individual. It interesting compare...
The fast and accurate detection of brain tumor locations has always been a focus research in the field neuroscience. main emphasis this paper is to propose potential intraoperative glioma localization technique. This study utilizes rapid high temporal resolution characteristics electrocorticography investigate electroactive properties region from functional variability perspective employs its differences detect location glioma. Analysis two-minute data shows that structural similarity cosine...