A5103049846- Advanced Sensor and Energy Harvesting Materials
- Conducting polymers and applications
- Neuroscience and Neural Engineering
- Tactile and Sensory Interactions
- Supercapacitor Materials and Fabrication
- Electrospun Nanofibers in Biomedical Applications
- Innovative Energy Harvesting Technologies
- Muscle activation and electromyography studies
- 3D Printing in Biomedical Research
- Polymer Surface Interaction Studies
- Nanoplatforms for cancer theranostics
- Advancements in Battery Materials
- Nanocluster Synthesis and Applications
- Plasmonic and Surface Plasmon Research
- Solar-Powered Water Purification Methods
- Pregnancy and Medication Impact
- Wireless Power Transfer Systems
- Advanced Materials and Mechanics
- Functional Brain Connectivity Studies
- Retinoids in leukemia and cellular processes
- Reproductive System and Pregnancy
- Nanoparticle-Based Drug Delivery
- Microbial Inactivation Methods
- Seaweed-derived Bioactive Compounds
- Graphene and Nanomaterials Applications
Foshan University
2020-2023
Beijing Institute of Nanoenergy and Nanosystems
2018-2022
Chinese Academy of Sciences
2018-2022
Stomatology Hospital
2022
Guilin Medical University
2022
Beijing National Laboratory for Molecular Sciences
2021
Peking University
2021
University of Chinese Academy of Sciences
2018-2020
Qingdao University of Science and Technology
2018
Institute of Process Engineering
2017
Abstract Implantable medical devices provide an effective therapeutic approach for neurological and cardiovascular diseases. With the development of transient electronics, a new power source with biocompatibility, controllability, bioabsorbability becomes urgent demand sciences. Here, various fully bioabsorbable natural‐materials‐based triboelectric nanogenerators (BN‐TENGs), in vivo, are developed. The “triboelectric series” five natural materials is first ranked, it provides basic...
Abstract Changes in endocardial pressure (EP) have important clinical significance for heart failure patients with impaired cardiac function. As a vital parameter evaluating function, EP is commonly monitored by invasive and expensive catheterization, which not feasible long‐term continuous data collection. In this work, miniaturized, flexible, self‐powered sensor (SEPS) based on triboelectric nanogenerator (TENG), integrated surgical catheter minimally implantation, reported. porcine model,...
Abstract Conductive, stretchable, environmentally‐friendly, and strain‐sensitive elastomers are attracting immense research interest because of their potential applications in various areas, such as human–machine interfaces, healthcare monitoring, soft robots. Herein, a binary networked elastomer is reported based on composite hydrogel polyvinyl alcohol (PVA) polyethyleneimine (PEI), which demonstrated to be ultrastretchable, mechanically robust, biosafe, antibacterial. The mechanical...
Assessment of muscle function is an essential indicator for estimating elderly health, evaluating motor function, and instructing rehabilitation training, which also sets urgent requirements mechanical sensors with superior quantification, accuracy, reliability. To overcome the rigidity vulnerability traditional metallic electrodes, we synthesize ionic hydrogel large deformation tolerance fast self-healing ability. And propose a stretchable, self-healing, skin-mounted (Triple S) active...
Implantable medical electronic devices are usually powered by batteries or capacitors, which have to be removed from the body after completing their function due non-biodegradable property. Here, a fully bioabsorbable capacitor (BC) is developed for life-time implantation. The BC has symmetrical layer-by-layer structure, including polylactic acid (PLA) supporting substrate, PLA nanopillar arrays, self-assembled zinc oxide nanoporous layer, and polyvinyl alcohol/phosphate buffer solution...
Abstract In this work, a nanogenerator‐controlled drug delivery system (DDS) for use in cancer therapy is successfully established. A new magnet triboelectric nanogenerator (MTENG) fabricated that can guarantee the contact and detach cycle between two friction layers effectively increase TENG output, up to 70 V after implantation. Using special structural design, without commonly used spacer, contacting‐mode MTENG ensure high consistent electricity output encapsulation Doxorubicin‐(DOX‐)...
On the basis of unique physicochemical properties graphene quantum dots (GQDs), we developed a novel type theranostic agent by loading anticancer drug doxorubicin (DOX) to GQD's surface and conjugating Cy5.5 (Cy) dye GQD though cathepsin D-responsive (P) peptide. Such agents demonstrated superior therapeutic performance both in vitro vivo because improved tissue penetration cellular uptake. More importantly, they are capable functioning as probes for programmed tracking delivery release well...
Abstract Wearable and portable electronics have brought great convenience. These battery‐powered commercial devices a limited lifetime require recharging, which makes more extensive applications challenging. Here, battery‐like self‐charge universal module (SUM) is developed, able to efficiently convert mechanical energy into electrical store it in one device. An integrated SUM consists of power management unit an harvesting unit. Compared other devices, ingenious, efficient can be...
Abstract Self‐powerability is a new trend in the development of portable devices. Harvesting biomechanical energy to power personal information electronics great significance. In this work, we report wearable noncontact free‐rotating hybrid nanogenerator (WRG), which constituted by triboelectric and an electromagnetic generator. A continuous output over 2 seconds can be achieved during one instantaneous incentive external force, improved two orders magnitude compared other nanogenerators due...
In this study, an intelligent drug delivery system (DDS) based on implanted triboelectric nanogenerator (iTENG) and red blood cell (RBC) is established for in situ hepatocellular carcinoma (HCC) therapy. Apatinib (APA), as oral antitumor drug, which can inhibit the expression of vascular endothelial growth factor receptor-2 (VEGFR2) loaded inside RBC, realizing transform from formulation to injection preparation. Multishape designed iTENG adapted different implant sites environments harvest...
With the advantages of being lightweight, flexible, and wearable, wire-shaped supercapacitors have received tremendous attention in wearable portable power sources recent years. Considering demands for large-scale applications, it is necessary to explore a facile convenient preparation approach supercapacitors. Herein, we reported simple fabricate electrodes by dipping method, which possessed nitric acid-activated graphite fiber core an activated carbon-coating layer structure. Parallel...
The efficacy of treating solid tumors with chemotherapy is primarily hindered by dose-limiting toxicity due to off-target effects and the heterogeneous drug distribution caused dense extracellular matrix. enhanced permeability retention (EPR) effect within restricts circulation diffusion drugs. To overcome these obstacles, hydrogels formed in situ at tumor site have been proposed promote accumulation, retention, long-lasting release. We developed a thiolated chitosan (CSSH) hydrogel gelation...
Catalytic therapy based on piezoelectric nanoparticles has become one of the effective strategies to eliminate tumors. However, it is still a challenge improve tumor delivery efficiency nanoparticles, so that they can penetrate normal tissues while specifically aggregating at sites and subsequently generating large amounts reactive oxygen species (ROS) achieve precise efficient clearance. In present study, we successfully fabricated microenvironment-responsive assembled barium titanate...
Abstract Hydration greatly affects ionic state in an aqueous environment and thus influences their electrochemical performance. In this study, three alkali metal chlorides dissolved neutral polyvinyl alcohol hydrogel are fully investigated for bendable solid‐state TiO 2 nanotube capacitor (BSTC). Radius difference between bare ions hydrated results obviously different makes lithium‐ion (Li + ) possess the largest radius lowest mobility, which endows it best capacitance performance BSTC by...
In article number 1808640, Wei Wei, Zhou Li, and co-workers develop an electric field-controlled drug delivery system based on triboelectric nanogenerators red blood cells for cancer treatment. Accelerated release of the occurs only when field is generated by a magnet nanogenerator. Highly efficient therapy demonstrated both in vitro vivo.
Abstract Self‐powered technology based on nanogenerators (NGs) has developed rapidly since the invention of NGs. This can transform mechanical energy into electrical and be applied to self‐powered healthcare systems. Meanwhile, after development five generations, drug dosage forms have entered era pulsed delivery system (DDS), which promotes application NGs in DDS. review first reviews type, working principle, materials, structure strategy Next, frontier applications as devices (DDDs),...
Polysaccharides derived from the flowers of Plumeria rubra (PRP) have shown a variety beneficial effects on improving human health. However, structural features and bioactivities PRP remain unclear. A novel neutral polysaccharide (named PRP-1) with molecular weight 23 kDa was extracted purified P. rubra. PRP-1 consisted arabinose, galactose, glucose, xylose mannose, molar ratio 1.49: 27.89: 50.24: 13.02: 7.36. The characterization based methylation 1D/2D nuclear magnetic resonance analyses...