A5070874951- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Ocular Diseases and Behçet’s Syndrome
- Diagnosis and treatment of tuberculosis
- Bacterial Infections and Vaccines
- Orthopedic Infections and Treatments
- Infectious Diseases and Mycology
- Antibiotic Resistance in Bacteria
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Microscopic Colitis
- Legionella and Acanthamoeba research
- Ocular Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Pneumocystis jirovecii pneumonia detection and treatment
- Reproductive tract infections research
- Cystic Fibrosis Research Advances
- Vibrio bacteria research studies
- Infections and bacterial resistance
- Tracheal and airway disorders
- Groundwater and Watershed Analysis
- Bacterial biofilms and quorum sensing
All India Institute of Medical Sciences
2010-2024
Post Graduate Institute of Medical Education and Research
2013-2024
All India Institute of Medical Sciences Raipur
2021-2024
All India Institute of Medical Sciences Bhopal
2021-2024
University of Manitoba
2024
Public Health Agency of Canada
2024
G.B. Pant Institute of Himalayan Environment and Development
2024
Ruxmaniben Deepchand Gardi Medical College
2024
Manipal Academy of Higher Education
2023
Punjab Engineering College
2022-2023
The increasing prevalence of extended-spectrum β-lactamases (ESBLs) has abated therapeutic options worldwide. This study was undertaken to investigate the molecular profile and resistance patterns ESBLs among clinical isolates Escherichia coli Klebsiella pneumoniae at four tertiary care centres in India.Clinical E. K. were collected from All India Institute Medical Sciences (AIIMS), New Delhi; Jawaharlal Postgraduate Education & Research (JIPMER), Puducherry; (PGIMER), Chandigarh Christian...
The helminthic parasites have largely been looked upon as chronic infections in developing countries causing morbidity. parasites, unlike other microbial pathogens, are unique the way they interact with host’s immune system. Their size, complexity, and movement within host trigger response toward a relative state of hyporesponsiveness, favoring cohabitation. This immunomodulation has topic much debate last decade. review explicitly explains how capable modulating system this is brought about...
<h3>Background</h3> Herpes Simplex Virus (HSV) keratitis is a leading cause of corneal blindness. Definitive laboratory diagnosis essential for timely management. Collection scrapings in patients with advanced epithelial and thinning poses perforation risks; tear fluid feasible convenient alternative but has not been widely evaluated HSV detection. <h3>Methods</h3> Tear alone (229) or along (153) from suspected herpetic was tested HSV-1 antigen by indirect immunofluorescence assay, virus...
Rapid and accurate diagnosis of tuberculous meningitis (TBM) is imperative for the optimal management patients. Loop-mediated isothermal amplification (LAMP) a promising nucleic-acid assay, especially resource-poor, endemic countries.Evaluating LAMP assay using insertion sequence (IS) 6110 MPB64 targets Mycobacterium tuberculosis complex (MTC) rapid TBM. Results were compared with culture composite reference standard.The was performed six MTC-specific primers each IS6110 on cerebrospinal...
Introduction: With the increasing threat of multidrug-resistant organisms, such as Acinetobacter baumannii, polymyxin class drugs (colistin and B) has become popular in clinical practice. A better understanding antimicrobial susceptibility testing methods for colistin B is needed optimal patient management. Materials Methods: Forty-two carbapenem-resistant A. baumannii isolates were subjected to using following methods: broth microdilution (BMD) (glass-coated plates [BMD-Gs] polystyrene...
Delay in diagnosing osteoarticular tuberculosis (OATB) contributes significantly to morbidity by causing disfiguration and neurological sequelae. The delay caused conventional culture the expertise expense involved other nucleic acid based tests, make LAMP (loop-mediated isothermal amplification) assay a favorable middle path. We evaluated using IS6110 MPB64 for rapid diagnosis of OATB comparing with PCR culture. was performed on 140 synovial fluid pus samples (10 culture-positive proven...
Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) has been instrumental in revolutionizing microbiological identification, especially high-throughput laboratories. It enabled the identification of organisms like non-fermenting Gram-negative bacilli (NFGNB), which a challenging task using conventional methods alone. In this study an attempt was made to validate MALDI-TOF MS for clinical isolates each three most common NFGNB, other than Pseudomonas...
Accurate and rapid identification of dipteran vectors is integral for entomological surveys a vital component control programs mosquito-borne diseases. Conventionally, morphological features are used mosquito identification, which suffer from biological geographical variations lack standardization. We matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) protein profiling species North India with the aim creating MALDI-TOF MS database evaluating it....
Background Truenat MTB Plus assay was evaluated for diagnosing ocular tuberculosis (OTB) and detecting multi-drug resistant (MDR) extremely-drug (XDR) OTB.Methods A total of 75 vitreous fluid specimens [five confirmed OTB, 40 clinically suspected OTB 30 controls] were subjected to Plus, multiplex PCR, Xpert Ultra. Chips used rifampicin, isoniazid, fluoroquinolone bedaquiline resistance. The performance compared against culture, composite reference standard, gene sequencing.Results overall...
SummaryIn a prospective, randomised trial, 100 pregnant women with ≥ one prior spontaneous pre-term birth were into two groups. Group 1 received mg natural micronised progesterone intravaginally once daily from 20–24 weeks' gestation until 36 weeks. 2 did not receive progesterone. Both groups regularly supervised delivery. Pre-term (<37 and <34 weeks) other maternal, neonatal outcomes primary secondary outcomes, respectively. Chi-square test Fisher exact used to compare categorical...
Candida auris has emerged as a serious threat to the health care settings. Advancements in molecular biology have provided several insights into evolution of C. since it was first described 2009. However, simultaneous emergence four different clades fungus at distinct geographical locations remains mystery. The hypotheses already proposed by researchers fall short explaining how and why emerged. In this article, we theorize that from common ancestor, subsequently migrated specific locations,...
Abstract Background and Aim Prompt accurate diagnosis of gastrointestinal tuberculosis (GITB) along with simultaneous detection drug resistance is inevitable for elimination. Truenat MTB Plus (TruPlus), a chip‐based real‐time polymerase chain reaction assay, was evaluated the first time diagnosing GITB detecting rifampicin resistance. Methods Fifty ileocecal biopsy specimens (5 microbiologically confirmed [culture‐positive], 25 clinically [culture‐negative], 20 control patients) processed in...
Maltose and low-molecular weight dextran inhibited the adherence of Streptococcus mutans to smooth glass surface scintillation vials. Inhibition paralleled inhibition insoluble glucan synthesis, confirming a role these polymers in mechanism. At maximum adherence, there was 60–70% decrease S. cells sticking surfaces. These results suggest that incorporation maltose or food stuffs should be investigated as measure reduce caries.