A5003125020- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Neonatal Respiratory Health Research
- Vaccine Coverage and Hesitancy
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Nosocomial Infections in ICU
- Intensive Care Unit Cognitive Disorders
- Obstructive Sleep Apnea Research
- Viral gastroenteritis research and epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Colorectal and Anal Carcinomas
- COVID-19 epidemiological studies
- Frailty in Older Adults
- Thermal Regulation in Medicine
- Mechanical Circulatory Support Devices
- COVID-19 and healthcare impacts
- Central Venous Catheters and Hemodialysis
- Colorectal Cancer Surgical Treatments
- Radiation Effects and Dosimetry
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Climate Change and Health Impacts
Hospital Israelita Albert Einstein
2017-2024
Hospital Sírio-Libanês
2010-2014
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2005
Universidade de São Paulo
1998
Alveolar overdistention and cyclic reopening of collapsed alveoli have been implicated in the lung damage found animals submitted to artificial ventilation. To test whether these phenomena are impairing recovery patients with acute respiratory distress syndrome (ARDS) conventional mechanical ventilation (MV), we evaluated impact a new ventilatory strategy directed at minimizing "cyclic parenchymal stretch." After receiving pre-established levels hemodynamic, infectious, general care, 28...
Abstract Objective: To determine risk factors for the development of long coronavirus disease 2019 (COVID-19) in healthcare personnel (HCP). Methods: We conducted a case–control study among HCP who had confirmed symptomatic COVID-19 working Brazilian system between March 1, 2020, and July 15, 2022. Cases were defined as those having COVID according to Centers Disease Control Prevention definition. Controls documented but did not develop COVID. Multiple logistic regression was used assess...
Abstract Background Little is currently known about vaccine effectiveness (VE) for either 2 doses of Oxford-AstraZeneca (ChAdOx1) viral vector or CoronaVac (Instituto Butantan) inactivated followed by a third dose mRNA (Pfizer/BioNTech) among healthcare workers (HCWs). Methods We conducted retrospective cohort study HCWs (aged ≥18 years) working in private system Brazil from January to December 2021. VE was defined as 1 – incidence rate ratio (IRR), with IRR determined using Poisson models...
Although there are simple and low-cost measures to prevent healthcare-associated infections (HAIs), they remain a major public health problem. Quality issues lack of knowledge about HAI control among healthcare professionals may contribute this scenario. In study, our aim is present the implementation project HAIs in intensive care units (ICUs) using quality improvement (QI) collaborative model Breakthrough Series (BTS).A QI report was conducted assess results national Brazil between January...
Abstract Objective: We investigated real-world vaccine effectiveness for Oxford-AstraZeneca (ChAdOx1) and CoronaVac against laboratory-confirmed severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare workers (HCWs). Methods: conducted a retrospective cohort study HCWs (aged ≥18 years) working in private system Brazil between January 1, 2021 August 3, 2021, to assess effectiveness. calculated as 1 − rate ratio (RR), with RR determined by adjusting Poisson models...
In 2009, during the influenza A (H1N1) epidemic, there were many reported cases of pulmonary infection with severe hypoxemia that was refractory to ventilatory strategies and rescue therapies commonly used treat patients acute respiratory distress syndrome. Many those treated extracorporeal membrane oxygenation (ECMO), which renewed international interest in technique. The Extracorporeal Support Study Group created order practice ECMO employ it treatment hypoxemia. this article, we discuss...
PASSOS AMATO, MARCELO BRITTO; VALENTE BARBAS, CARMEN SILVIA; MEDEIROS, DENISE MACHADO; MAGALDI, RICARDO BORGES; PAULA PINTO SCHETTINO, GUILHERME DE; LORENZI-FILHO, GERALDO; KAIRALLA, RONALDO ADIB; DEHEINZELIN, DANIEL; MUNOZ, CARLOS; OLIVEIRA, ROSELAINE; TAKAGAKI, TERESA YAE; RIBEIRO CARVALHO, CARLOS ROBERTO Author Information
ABSTRACT Objectives We aimed to determine risk factors for the development of long coronavirus disease (COVID) in healthcare workers (HCWs). Methods conducted a case-control study among HCWs who had confirmed COVID-19 infection working Brazilian system between March 1, 2020 and July 15, 2022. Cases were defined as those having COVID per Centers Disease Control Prevention definition. Controls documented but did not develop COVID. Multiple logistic regression was used assess association...
Abstract Background In pressure support ventilation (PSV), a non-variable level of is delivered by the ventilator when triggered patient. contrast, variable PSV delivers that varies in random fashion, introducing more physiological variability to respiratory pattern. Experimental studies show improves gas exchange, reduces lung inflammation and mean support, compared PSV. Thus, it can theoretically shorten weaning from mechanical ventilator. Methods/design The ViPS (variable support) trial...
Abstract Objective: To compare the long-term vaccine effectiveness between those receiving viral vector [Oxford-AstraZeneca (ChAdOx1)] or inactivated (CoronaVac) primary series (2 doses) and who received an mRNA booster (Pfizer/BioNTech) (the third dose) among healthcare workers (HCWs). Methods: We conducted a retrospective cohort study HCWs (aged ≥18 years) in Brazil from January 2021 to July 2022. assess variation of dose over time, we estimated rate by taking log risk ratio as function...
The TELE-critical Care verSus usual On ICU PErformance (TELESCOPE) trial aims to assess whether a complex telemedicine intervention in intensive care units, which focuses on daily multidisciplinary rounds performed by remote intensivists, will reduce unit length of stay compared care.The TELESCOPE is national, multicenter, controlled, open label, cluster randomized trial. study tests the effectiveness conducted an intensivist through Brazilian units. protocol was approved local Research...
OBJETIVOS: Apesar da ressuscitação volêmica guiada por saturação venosa central de oxigênio (SvcO2) ser considerada atualmente padrão ouro no tratamento sepse, poucos estudos caracterizaram o perfil evolutivo variáveis hemodinâmicas e perfusionais durante esta abordagem terapêutica. Este estudo teve objetivo descrever evolutivamente estes parâmetros choque séptico experimental sem após 12 horas metas. MÉTODOS: Treze porcos (35-45 kg) anestesiados foram submetidos a peritonite inoculação...
No Brasil, o primeiro paciente com a doença do coronavírus 2019 (COVID-19) foi diagnosticado em 26 de fevereiro 2020. Morava São Paulo (SP) e retornara recentemente uma viagem da Europa. Ao longo das semanas seguintes, maioria dos novos casos COVID-19 tinha um fator risco epidemiológico identificável – ter viajado ao exterior ou tido contato que sabidamente estava síndrome respiratória aguda grave 2 (SARS-CoV-2). entanto, como as [...]
145 Background: Despite the growing palliative care movement, most admissions still occur in Intensive Care Units. The aim of this study was to determine frequency patients admitted an ICU and assessed their outcomes. Methods: This prospective conducted a tertiary private hospital, adult medical-surgical with 22-bed São Paulo, Brazil. Patients or family member stay ≥ 48 hours were invited participate. They excluded if they had no conditions answer questionnaire refuse During we analyzed...
To study the incidence and predictors of post-traumatic stress, anxiety depression symptoms in medical surgical patients relatives during ICU stay at 30 90 days post discharge.