A5073545513- Autoimmune Bullous Skin Diseases
- Leprosy Research and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Research on Leishmaniasis Studies
- Urticaria and Related Conditions
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Trypanosoma species research and implications
- Nosocomial Infections in ICU
- Oral and gingival health research
- Patient Safety and Medication Errors
- Antibiotic Use and Resistance
- Healthcare Quality and Management
- Hepatitis Viruses Studies and Epidemiology
- Central Venous Catheters and Hemodialysis
- Viral Infections and Vectors
- Infection Control in Healthcare
- Mosquito-borne diseases and control
- Hematological disorders and diagnostics
- Medical Malpractice and Liability Issues
- Vector-Borne Animal Diseases
- Blood disorders and treatments
- Skin Diseases and Diabetes
- Venomous Animal Envenomation and Studies
- Forensic and Genetic Research
Hospital Moinhos de Vento
2023-2025
Hospital Alemão Oswaldo Cruz
2023-2025
Hospital Israelita Albert Einstein
2023-2025
Hospital Sírio-Libanês
2023-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021-2025
Beneficência Portuguesa de São Paulo
2023-2025
Universidade de São Paulo
2016-2024
Clinics Hospital of Ribeirão Preto
2016-2024
New York Proton Center
2023
Communities In Schools of Orange County
2023
Background Leprosy diagnosis is mainly based on clinical evaluation, although this approach difficult, especially for untrained physicians. We conducted a temporary campaign to detect previously unknown leprosy cases in midwestern Brazil and compare the performance of different serological tests. Methods A mobile clinic was stationed at main bus terminal Brasília, Brazil. Volunteers were quizzed given exam allow categorization as either patients, known contacts patients or non-contacts,...
Show that hidden endemic leprosy exists in a municipality of inner São Paulo state (Brazil) with active surveillance actions based on clinical and immunological evaluations.The study sample was composed by people randomly selected dermatologist during medical care the public emergency department carried out two days at mobile clinic. All subjects received dermato-neurological examination blood sampling to determine anti-PGL-I antibody titers enzyme-linked immunosorbent assay (ELISA).From...
ABSTRACT The precise diagnosis of American tegumentary leishmaniasis (ATL) is an essential task due to the disease's associated morbidity. A noninvasive, extremely sensitive, and highly specific exam critical, particularly for mucosal (ML), in which a low parasite quantity expected. We aimed compare diagnostic accuracy swab biopsy sample analysis using SYBR Green- TaqMan-based real-time PCR (qPCR) assays with that composite reference standard consisting Montenegro skin test, serology,...
ABSTRACT Introduction Integrating process improvement tools into healthcare has shown promising results, yet the application of “training within industry” (TWI) still needs to be explored in this context. This study focuses on implementing job instruction (JI), one three components TWI, a large breakthrough series collaborative (BTS) middle-income country. Methods We evaluated deployment JI during nationwide initiative aimed at reducing critical healthcare-associated infections...
Background Syphilis remains a global health challenge, with rising incidence rates worldwide Prevalence surveys conducted in Brazil over extended periods of time are scarce. This study examines the secular trends and risk factors for syphilis seroprevalence among first-time blood donors Brazil. Methods A retrospective analysis was as part multicenter, repeated cross-sectional survey from four major Brazilian centers, covering period 2007 to 2020. First-time who had undergone valid treponemal...
Although there are simple and low-cost measures to prevent healthcare-associated infections (HAIs), they remain a major public health problem. Quality issues lack of knowledge about HAI control among healthcare professionals may contribute this scenario. In study, our aim is present the implementation project HAIs in intensive care units (ICUs) using quality improvement (QI) collaborative model Breakthrough Series (BTS).A QI report was conducted assess results national Brazil between January...
BackgroundHealthcare-associated infections (HAIs) have a significant impact on patients' morbidity and mortality, detrimental financial the healthcare system. Various strategies exist to prevent HAIs, but economic evaluations are needed determine which most appropriate.AimTo present of nationwide project HAI prevention in intensive care units (ICUs) using quality improvement (QI) approach.MethodsA health evaluation assessed results QI initiative ‘Saúde em Nossas Mãos’ (SNM), implemented...
Background Every year, millions of patients suffer injuries or die due to unsafe and poor-quality healthcare. A culture safety care is crucial prevent risks, errors harm that may result from medical assistance. Measurement patient (PSC) identifies strengths weaknesses, serving as a guide improvement interventions; nevertheless, there lack studies related PSC in Latin America. Aim To assess the South American hospitals. Methods multicentre international cross-sectional study was performed...
Background The Breakthrough Series model uses learning sessions (LS) to promote education, professional development and quality improvement (QI) in healthcare. Staff divergences regarding prior knowledge, previous experience, preferences motivations make selecting which pedagogic strategies use LS a challenge. Aim We aimed assess new active-learning strategies: two educational games, card game an escape room-type game, for training healthcare-associated infection prevention. Methods This...
Well-defined locations of pemphigus cases support the hypothesis environmental factors' involvement in its etiopathogenesis; however, these foci have never been described using specialized geographical tools. This is first report to geo-reference a high-prevalence Brazilian region geographic information systems. We aimed spatio-temporal behavior foliaceus (PF) and vulgaris (PV) southeastern Brazil, over last five decades describe clusters, as well characterize land use city with highest...
Background: Cutaneous leishmaniasis is distributed worldwide, including Brazil. Its several clinical forms need to be distinguished from other dermatoses. Clinical similarities and lack of a gold standard diagnostic tool make leishmaniasis-like lesions challenging diagnosis. Objectives. To report the final diagnosis patients primarily suspected having American tegumentary (ATL). Methods. A retrospective cross-sectional study was conducted on basis medical records 437 with suspicion ATL,...
Abstract Background. Disseminated leishmaniasis (DL) is an emerging clinical form of American tegumentary (ATL) that occurs mainly in Northeastern Brazil. This study describes 18 cases where DL has not yet been reported. Methods. were extracted from ATL recorded between 1987 and March 2015. identification was based on ≥10 mixed-type lesions, located ≥2 body parts. Results. Eighteen (5.4%) patients identified as DL. Polymerase chain reaction followed by enzymatic digestion confirmed...
Beginning in 2018, a quality improvement collaborative initiative Brazil successfully reduced the baseline incidence density of healthcare-associated infections intensive care settings after 2 years. We describe adaptations interventions as COVID-19 pandemic emerged and how affected project outcomes.
Anti-desmoglein 1 and 3 autoantibodies justify acantholysis in pemphigus; however, the pathogenesis of anti-desmoglein 2 is hypothetical.To compare participation desmogleins 1, through production serum autoantibodies, protein gene expression skin/mucosa patients with pemphigus foliaceus vulgaris.The were titrated by ELISA 202 samples foliaceus, 131 vulgaris, 50 57 relatives respectively, 114 controls. Protein expressions determined immunohistochemistry qPCR vulgaris.Higher titers (optical...