A5072705945- Autoimmune Bullous Skin Diseases
- Research on Leishmaniasis Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- Leprosy Research and Treatment
- Nail Diseases and Treatments
- Trypanosoma species research and implications
- Porphyrin Metabolism and Disorders
- Cutaneous lymphoproliferative disorders research
- Oral and gingival health research
- Dermatology and Skin Diseases
- Autoimmune and Inflammatory Disorders
- Nonmelanoma Skin Cancer Studies
- Drug-Induced Adverse Reactions
- Dermatological and COVID-19 studies
- Hair Growth and Disorders
- Fungal Infections and Studies
- Medicine and Dermatology Studies History
- Syphilis Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Systemic Lupus Erythematosus Research
- T-cell and Retrovirus Studies
- Infectious Diseases and Mycology
- Food Allergy and Anaphylaxis Research
- Platelet Disorders and Treatments
Universidade de São Paulo
2015-2024
Clinics Hospital of Ribeirão Preto
2014-2024
Universidade de Ribeirão Preto
2008-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2022
ORCID
2021
Hospital de Câncer de Barretos
2020
Universidade Estadual de Ponta Grossa
2019
Universidade Brasil
2000-2015
Academia Nacional de Medicina
2006
Endogenous regulatory T (Treg) cells are involved in the control of infections, including Leishmania infection mice. viannia braziliensis is main etiologic agent cutaneous leishmaniasis (CL) Brazil, and it also responsible for more severe mucocutaneous form. Here, we investigated possible involvement Treg immune response human skin lesions caused by L. infection. We show that functional can be found patients with CL. These express phenotypic markers cells--such as CD25, cytotoxic...
Bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita are subepidermal autoimmune blistering diseases whose antigenic target is located at the basement zone. Mucous can evolve with cicatricial mucosal involvement, leading to respiratory, ocular and/or digestive sequelae important morbidity. For each of these dermatoses, a literature review covering all therapeutic options was performed. A flowchart, based on experience joint discussion among authors this...
ABSTRACT The precise diagnosis of American tegumentary leishmaniasis (ATL) is an essential task due to the disease's associated morbidity. A noninvasive, extremely sensitive, and highly specific exam critical, particularly for mucosal (ML), in which a low parasite quantity expected. We aimed compare diagnostic accuracy swab biopsy sample analysis using SYBR Green- TaqMan-based real-time PCR (qPCR) assays with that composite reference standard consisting Montenegro skin test, serology,...
More precise and rapid diagnostic methods for American cutaneous leishmaniasis (ACL) are necessary because of the growing number cases observed in Brazil, including northeastern region State São Paulo. We applied PCR to 54 skin or mucosal biopsies from patients with a clinical and/or laboratory diagnosis ACL using primers 13A 13B, positive results being obtained 82% samples. When were compared those histopathological leishmania detection, showed superior 81.5% sensitivity 95% CI 68.0-95.1%....
A great number of lichenoid lesions have overlapping clinicopathological features, so the use adjunct tests to establish definitive diagnosis is recommended for correct management and prognosis lesions. In this context, direct immunofluorescence (DIF) can be a useful tool. Thus, study aimed characterize clinical, histopathological, DIF pattern in patients with oral lichen planus (OLP) (OLLs). Patients OLP OLL were characterized compared mucous membrane pemphigoid, pemphigus vulgaris, fibrous...
Leishmaniasis is a parasitic disease with diverse clinical manifestations, and considered public health problem in endemic countries such as Brazil. Mucosal lesions usually involve the upper respiratory tract, predilection for nose larynx. Oral involvement unusual most cases it becomes evident after several years of resolution original cutaneous lesions. classically appear mucosal ulcerations, mainly hard or soft palate. This report describes clinicopathological data 11 mucocutaneous...
There are two main clinical subsets of pemphigus: pemphigus vulgaris and foliaceus. Clinical epidemiological changes related to both types have been observed in the last years.To analyze a 21-year historical case series foliaceus northeast region state Sao Paulo, where is endemic.In this descriptive study, data annual incidence age onset symptoms compatible with or were analyzed, comparing forms, period from 1988 2008.The overall results cover 21 years, 103 cases 163 An evaluation trend...
This paper presents color image processing methods for the analysis of dermatological images in context a content-based retrieval (CBIR) system. Tests were conducted on classification tissue components skin lesions, terms necrotic tissue, fibrin, granulation, and mixed composition. The classified based by an expert dermatologist following black-yellow-red model. Indexing performed texture information obtained from red, green, blue, hue, saturation images. performance CBIR system was measured...
Pemphigus foliaceus (PF) is a complex autoimmune disease characterized by bullous skin lesions and the presence of antibodies against desmoglein 1. In this study we sought to contribute better understanding molecular processes in endemic PF, as identification factors that participate pathogenesis prerequisite for its biological basis may lead novel therapeutic interventions. CD4+ T lymphocytes are central development disease. Therefore, compared genome-wide gene expression profiles...
Background: Pentavalent antimonials have became of basic importance for the treatment leishmaniasis. Their most severe side effects been reported to be increased hepatic enzyme levels and electrocardiographic abnormalities. Nephrotoxicity has rarely related. Observations: We report a case generalized cutaneous leishmaniasis involving 50-year old male patient who was submitted with meglumine antimoniate (Glucantime). He developed acute renal failure (ARF) due tubular necrosis (ATN), followed...
Well-defined locations of pemphigus cases support the hypothesis environmental factors' involvement in its etiopathogenesis; however, these foci have never been described using specialized geographical tools. This is first report to geo-reference a high-prevalence Brazilian region geographic information systems. We aimed spatio-temporal behavior foliaceus (PF) and vulgaris (PV) southeastern Brazil, over last five decades describe clusters, as well characterize land use city with highest...
Background: Cutaneous leishmaniasis is distributed worldwide, including Brazil. Its several clinical forms need to be distinguished from other dermatoses. Clinical similarities and lack of a gold standard diagnostic tool make leishmaniasis-like lesions challenging diagnosis. Objectives. To report the final diagnosis patients primarily suspected having American tegumentary (ATL). Methods. A retrospective cross-sectional study was conducted on basis medical records 437 with suspicion ATL,...