A5103063551- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Intraperitoneal and Appendiceal Malignancies
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- PARP inhibition in cancer therapy
- Renal cell carcinoma treatment
- Maternal and fetal healthcare
- Reproductive tract infections research
- Pregnancy and preeclampsia studies
- Minimally Invasive Surgical Techniques
- Pelvic floor disorders treatments
- Cancer Immunotherapy and Biomarkers
- Cancer Risks and Factors
- Enhanced Recovery After Surgery
- Immune cells in cancer
- Syphilis Diagnosis and Treatment
- Viral-associated cancers and disorders
- Sarcoma Diagnosis and Treatment
- Amoebic Infections and Treatments
- Immunotherapy and Immune Responses
- Reproductive Biology and Fertility
- Maternal and Perinatal Health Interventions
- Breast Cancer Treatment Studies
National Taiwan University Hospital
2015-2025
Houston Methodist
2025
National Taiwan University
2010-2024
Methodist Hospital
2024
Hesco (United States)
2024
Engineering Service Center und Handel (Germany)
2024
National Chung Cheng University
2023
Beijing Obstetrics and Gynecology Hospital
2020
Far Eastern Memorial Hospital
2019
Materials Science & Engineering
2016
The purpose of this study was to establish a consensus on the surgical technique for sentinel lymph node (SLN) dissection in cervical cancer.
MicroRNAs (miRNAs) play critical roles in embryonic development and are frequently deregulated human cancers. The let-7 family members tumor-suppressing miRNAs downregulated cancer cells. Lin-28 Lin-28B RNA-binding proteins highly expressed tissues. block precursors from being processed to mature by inducing terminal uridylation degradation of precursors. Here, we report that Lin-28B, but not Lin-28, is hepatocellular carcinoma (HCC). expression was more noted high-grade HCCs with high...
Epidemiological studies have shown that maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) are associated with increased risk of perinatal outcomes. However, the evidence such associations in Asian populations is limited. We conducted a secondary data analysis to investigate relationships BMI GWG risks adverse outcomes, including diabetes (GDM), hypertension (GHTN), preeclampsia, cesarean delivery, preterm birth, low birth (LBW), macrosomia. categorized by WHO...
The immuno-inhibitory checkpoint PD-L1, regulated by tumor cells and antigen-presenting (APCs), dampened the activation of T from PD-1/PD-L1 axis. PD-L1-expressing APCs rather than demonstrated essential anti-tumor effects anti-PD-L1 monotherapy in preclinical models. Using murine model, we investigated whether antibody increased antigen-specific immune response induced protein vaccine, as well possible mechanisms regarding APCs. Anti-PD-L1 combined with PEK vaccine generated more potent...
Trichomoniasis (TV), bacterial vaginosis (BV), and vulvovaginal candidiasis (VVC) are the most common causes of vaginitis. This study investigated prevalence these diagnoses, their associated factors, appropriateness empirical treatment. From March 25, 2019, to June 17, 2022, 429 women with symptoms or signs vaginitis were enrolled in a hospital northern Taiwan 438 episodes Vaginal swabs collected for Gram's staining, vitro cultures Trichomonas vaginalis, bacteria, yeasts, multiplex PCR...
This study was designed to investigate the demographics, treatment patterns, and clinical outcomes of patients newly diagnosed with high-grade serous ovarian cancer (HGSOC) in 3 medical centers Taiwan before integration poly (ADP-ribose) polymerase inhibitors practice. A retrospective analysis conducted on data from HGSOC between January 2014 December 2018 followed-up for a minimum 12 months after diagnosis. Descriptive statistics were used analyze data, while survival rates evaluated using...
In this retrospective study, we investigated adverse events and outcomes in patients treated with bevacizumab for ovarian, fallopian tube, or primary peritoneal cancers at a single hospital. We determined the cumulative incidences of various bevacizumab-related correlation between dose event incidences. analyzed data from 154 that received 251 rounds as first-line, first salvage, >2 salvage treatments. Adverse any grade were observed 121 (78.6%) patients; least one 3 4 occurred 32 (20.8%)...
Abstract Background Fertility‐sparing surgery (FSS) is an alternative choice of young patients who have not completed their family planning and still fertility needs. The aims this study were to compare the outcomes early‐stage epithelial ovarian cancer (EOC) undergoing FSS radical comprehensive staging (RCS), suitability FSS. Methods A total 1297 aged between 20 44 years with newly diagnosed EOC recruited from Taiwan Cancer Registry database 2009 2017. Site‐specific codes used distinguish...
The objective of this article was to report the clinicopathological characteristics, treatment modalities, and outcomes patients with clear cell carcinoma (CCC) abdominal wall. Medical records six diagnosed CCC wall between May 2003 2018 at National Taiwan University Hospital were reviewed. All had prior obstetric or gynecologic surgeries. primary clinical presentation enlarging masses previous surgical scars. Four underwent initial/primary surgeries with/without adjuvant chemotherapy. One...
We aimed to determine prognostic factors of early stage (I/II) epithelial ovarian carcinoma (EOC) including clinicopathologic and chemotherapeutic regimens. Four hundred thirty-seven women who underwent primary staging surgery with adjuvant chemotherapy between January 1, 2000 December 31, 2010 were retrospectively reviewed analyzed from two medical centers. The determined multivariate survival analyses using Cox regression models. majority diagnosed Ic (244/437, 55.8%). histopathologic...
Mother and newborn skin-to-skin contact (SSC) after birth has numerous protective effects. Although positive associations between SSC breastfeeding behavior have been reported, the evidence for such early success was limited in high-income countries. This quasi-experimental intervention design study aimed to evaluate impact of different regimens on outcomes Taiwan. In total, 104 healthy mother-infant dyads (52 group 52 control group) with normal vaginal delivery were enrolled from 1 January...
We aimed to identify factors predicting parametrial invasion in early-stage cervical cancer patients undergoing radical hysterectomy. recruited women with invasive who underwent hysterectomy at a single medical institute from 2000-2011. The clinical and pathological characteristics outcomes were retrospectively recorded, the risk for analyzed. enrolled 339 patients, including 7 stage IA1 carcinomas, 10 IA2, 266 IB1, 39 IB2, 14 IIA1, 3 IIA2. majority (237/339, 69.9%) had squamous cell...
We evaluated the prevalence of and risk factors for hypersensitivity reactions related to carboplatin, which is commonly used treat gynecological malignancies. All women with pathologically documented ovarian, fallopian tube, or primary peritoneal cancer treated carboplatin alone a carboplatin-based combination chemotherapy regimen at single hospital between January 2006 December 2013 were retrospectively recruited. analyzed incidence, characteristics, factors, management, outcomes...