Paola Ortelli

ORCID: 0000-0002-6845-520X
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About
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Research Areas
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Long-Term Effects of COVID-19
  • Cerebral Palsy and Movement Disorders
  • Indigenous Cultures and Socio-Education
  • Botulinum Toxin and Related Neurological Disorders
  • Dementia and Cognitive Impairment Research
  • Transcranial Magnetic Stimulation Studies
  • Vestibular and auditory disorders
  • Balance, Gait, and Falls Prevention
  • Action Observation and Synchronization
  • Autism Spectrum Disorder Research
  • Public Policy and Governance
  • Heart Rate Variability and Autonomic Control
  • Sleep and Wakefulness Research
  • Attention Deficit Hyperactivity Disorder
  • Alzheimer's disease research and treatments
  • Legal and Labor Studies
  • Neurobiology of Language and Bilingualism
  • Muscle activation and electromyography studies
  • Epilepsy research and treatment
  • Obsessive-Compulsive Spectrum Disorders
  • Regional Development and Innovation
  • Neuroscience and Neuropharmacology Research
  • Spatial Neglect and Hemispheric Dysfunction

Ospedale di Bolzano
2025

Ospedale Amedeo di Savoia
2024

Studio Odontoiatrico Mangano
2020-2024

Paracelsus Medical University
2022-2024

Krankenhaus Brixen
2023

Moriggia Pelascini Hospital
2016-2023

Policlinico San Matteo Fondazione
2019

Istituti di Ricovero e Cura a Carattere Scientifico
2019

Ibero American University
2018

Autonomous University of Chiapas
2011-2017

Background: Subjects with amnesic mild cognitive impairment (aMCI) may include patients at high risk for progression to Alzheimer disease (AD) and a population different underlying pathologic conditions.Objective: To evaluate the potential roles of positron emission tomography fluodeoxyglucose F 18 ( FDG-PET) memory scores in identifying subjects aMCI predicting dementia.Design, Setting, Patients: Sixty-seven European centers neurologic AD care who were diagnosed as having each underwent an...

10.1001/archneur.62.11.1728 article EN Archives of Neurology 2005-11-01

Action naming has been reported to be disproportionately impaired in comparison object patients with frontotemporal dementia (FTD). This finding attributed the crucial role of frontal cortex action naming. The investigation and different subtypes FTD, as well related conditions progressive supranuclear palsy (PSP) corticobasal degeneration (CBD), may thus contribute elucidation cerebral correlates action-object discrepancy provide clues underlying cognitive mechanisms. results indicated...

10.1037/0894-4105.20.5.558 article EN Neuropsychology 2006-08-28

Objective To evaluate whether a 4-week multidisciplinary, aerobic, motor-cognitive and intensive rehabilitation treatment (MIRT) improves the quality of life (QoL) patients with Parkinson’s disease (PD), in short-term long-term period. Methods This is prospective, parallel-group, single-centre, single-blind, randomised clinical trial (ClinicalTrials.gov NCT02756676 ). 186 PD, assigned to experimental group, underwent MIRT; conversely, 48 patients, control did not receive rehabilitation....

10.1136/jnnp-2017-316437 article EN cc-by-nc Journal of Neurology Neurosurgery & Psychiatry 2018-01-10

Fatigue and cognitive difficulties are reported as the most frequently persistent symptoms in patients after mild SARS-CoV-2 infection. An extensive neurophysiological neuropsychological assessment of such was performed focusing on motor cortex physiology executive functions.Sixty-seven complaining fatigue and/or resolution infection were enrolled together with 22 healthy controls (HCs). Persistent clinical investigated by means a 16-item questionnaire. Fatigue, exertion, difficulties, mood...

10.1111/ene.15278 article EN European Journal of Neurology 2022-02-09

To study awareness of cognitive dysfunction in patients with very mild Alzheimer's disease (AD) and subjects impairment (MCI).A complaint interview covering 13 domains was administered to 82 AD 79 MCI their caregivers. The patient groups were comparable according age education, Mini Mental State Examination (MMSE) scores > or =24 all cases. discrepancy between the patients' caregivers' estimations impairments taken as a measure anosognosia.Self-reports difficulties for patients. However,...

10.1159/000084704 article EN Dementia and Geriatric Cognitive Disorders 2005-01-01

To assess the longitudinal course of cognitive functions in a cohort patients with idiopathic REM sleep behavior disorder (iRBD).

10.1093/sleep/34.5.619 article EN SLEEP 2011-05-01

Background/Objectives: Parkinson’s disease (PD) is a complex neurodegenerative disorder responsible for both motor and non-motor disturbances impairing behavior. This complexity necessitates integrated, multidisciplinary, comprehensive models of care. A new interesting complementary approach represented by “Dance Well”, i.e., an artistic, multisensory dance intervention based on art music. pilot study aims to evaluate the efficacy, feasibility, safety 4-week Dance Well (DW) program in PD...

10.3390/brainsci15040357 article EN cc-by Brain Sciences 2025-03-29

We evaluated the efficacy of muscle-targeted nutritional support on functional outcomes multidisciplinary intensive rehabilitation treatment (MIRT) in patients with Parkinson disease (PD) or parkinsonism.We conducted a pragmatic, bicentric, randomized (1:1), assessor-blind controlled trial (Protein, Leucine and Vitamin D Enhancing Rehabilitation [PRO-LEADER]; April 2017 to January 2018) cognitively intact PD parkinsonism undergoing 30-day MIRT. Patients (n = 150) received standard hospital...

10.1212/wnl.0000000000007858 article EN Neurology 2019-07-06

Introduction. The evidence for the clinical effectiveness of cognitive rehabilitation in patients with Alzheimer’s Disease (AD) is debated. Therefore it important to collect more about outcome non‐pharmacological therapy dementia. Material and Methods. We report data concerning 50 probable AD admitted during a 17‐month period specialized unit. Participants were affected by dementia ranging from mild severe. treated Reality Orientation Therapy (ROT), integrated, when needed, individualised...

10.1155/2007/782959 article EN cc-by Behavioural Neurology 2007-01-01

Freezing of gait (FOG) is one the most disabling symptoms Parkinson disease (PD). Different land-based rehabilitation approaches based on motor and cognitive strategies can be effective in treating FOG. Although there are data about efficacy aquatic therapy ameliorating this phenomenon, no study has explored combined effect therapies plus patients with PD who have FOG.The objective was to investigate effectiveness a multidisciplinary, intensive, motor-cognitive treatment (MIRT) improving FOG...

10.1093/ptj/pzz003 article EN Physical Therapy 2019-01-09

Abstract Fatigue, attentional deficits and cognitive fluctuations are the most characterizing symptoms of neurological involvement in Post COVID-19 syndrome (PCS). As intraindividual variability (IIV) performances has been recognized as a hallmark brain-related disorders associated with deficits, it could be an interesting measure to elucidate mechanisms subtending both attentive impairment these patients. By referring IIV analysis Reaction Times (RTs), present study aims define its relation...

10.1038/s41598-022-17463-x article EN cc-by Scientific Reports 2022-07-30

In post-COVID-19 syndrome (PCS), neurocognitive symptoms and fatigue are often associated with alterations in electroencephalographic (EEG) activity. The present study investigates the brain source activity at rest PCS patients (PCS-pts) perceiving cognitive deficits fatigue. A total of 18 PCS-pts healthy controls (HCs) were enrolled. Montreal Cognitive Assessment (MoCA), Perceived Difficulties Scale (PDCS) Fatigue Severity (FSS) administered for assessing symptoms' severity. Brain rest,...

10.3390/biomedicines11082228 article EN cc-by Biomedicines 2023-08-08

The assessment of cognitive deficits is pivotal for diagnosis and management in patients with parkinsonisms. Low levels correspondence are observed between evaluations assessed screening tests comparison those in-depth neuropsychological batteries. A new tool, we named CoMDA (Cognition Movement Disorders Assessment), was composed by merging Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Battery (FAB). In total, 500 (400 Parkinson's disease, 41 vascular...

10.1038/s41531-022-00304-z article EN cc-by npj Parkinson s Disease 2022-04-11

Abstract We measured expression of central nervous system GABA‐A receptors with 11 C‐flumazenil ( C‐FMZ) and PET in two subjects stiff person syndrome (SPS). found reduced C‐FMZ binding potential (BP) motor‐premotor cortex, increased BP the cerebellar nuclei. This is first vivo evidence dysfunction SPS, possibly concurring to motor symptoms. © 2007 Movement Disorder Society

10.1002/mds.21441 article EN Movement Disorders 2007-03-07

Parkinsonian patients in advanced stages of disease suffer from many motor and non-motor symptoms, whose responsiveness to dopamine replacement therapy deep brain stimulation is poor. It necessary find complementary strategies order improve the clinical conditions Parkinson's (PD) stages.We aimed understand whether an inpatient, motor-cognitive, multidisciplinary, aerobic, intensive goal-based rehabilitation treatment (MIRT), specifically designed for PD, effective disease.638 patients,...

10.3233/jpd-171247 article EN Journal of Parkinson s Disease 2018-02-17

Background: The cognitive status is generally considered as a major determinant of rehabilitation outcome in Parkinson's disease. No studies about the effect impairment on motor outcomes disease have been performed before. Objective: This study aimed to evaluate impact decline patients with Methods: We retrospectively identified 485 hospitalized for 4-week Multidisciplinary Intensive Rehabilitation Treatment between January 2014 and September 2015. According Mini Mental State Examination...

10.3389/fnagi.2016.00192 article EN cc-by Frontiers in Aging Neuroscience 2016-08-11
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